RADICAL SCAVENGING AND CYTOTOXICITY EVALUATION OF EIGHT EXTRACTS OF CITRUS LIMON AND CITRUS AURANTIFOLIA
No Thumbnail Available
Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Nigerian Journal of Natural Product and Medicines
Abstract
Cancer is a global cause of death characterized by uncontrolled proliferation and spread of abnormal cells. Eight extracts composed of the leaf, stem bark,
seeds and juice of each of Citrus limon and C. aurantifolia were subjected to in vitro antioxidant assay using DPPH, brine shrimp lethality bioassay
of 28.2±0.11 and 47.2±0.39
µg/mL, respectively and displayed better radical scavenging activity compared to the other extracts, Ascorbic acid, the reference drug, had an IC
of
9.2±0.14 µg/mL. Citrus limon stem bark
50
=10.0±0.33
= 5.0±0.74 µg/mL
50
50
=98.76±0.15 µg/mL
50
=4.02±2.85 µg/mL, CC
50
=5.45±2.8 µg/mL
=2.23±0.14 µg/
mL, CC
=2.66±0.8 µg/mL
50
50
50
50
Description
Keywords
Cancer, abnormal cells, Citrus limon and C