Antibiotics Sensitivity Profile Of Proteus Species Associated With Specific Infections at University Of Ilorin Teaching Hospital, Ilorin
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Date
2017
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Published by College of Health Sciences, University of Ilorin
Abstract
Proteus is a proiitiiieni member ol llie I'amily
Enterobacteriaeeae responsible for a variety ot'
infections in human, such infections include urinary
tract infection and many other opportunistic infections
in human. The threat of antimicrobial resistance among
important isolates is of great concern. This study was
conducted to deteniiine the prevalence and antibiotic
sensitivity pattern of Proteus spp associated with its
specific infections at the University of llorin Teaching
Hospital llorin. A retrospective review of cultures
results of urine, wound swabs, ear and throat swabs
were analysed. A total of 1,500 clinical samples were
examined for identification of bacteria and their
antimicrobial susceptibility. The greatest number of
Proteus spp isolates were from wound swabs, 57.1%.
followed by mid-stream urine 20.4%. Males were
found to be more vulnerable than females in acquiring
Proteus infections, 53.1% and 46.9% respectively.
Results of the antimicrobial sensitivity testing showed
that Imipenem and Piperacillin antibiotics were the
most effective against Proteus spp with each having
100%, follow'ed by Ceftazidime 79.2%, and Ofloxacin
76.5%. The least effective antibiotic against Proteus
was Augmentin 58.1% sensitivity. It is therefore
recommended that Imipenem and Piperacillin should
be used in the treatment of Proteus infections, and
where both are not affordable. Ceftazidime and
Ofloxacin could be used in the study area for the
treatment of infections caused by Proteus. Regular
monitoring of antimicrobial susceptibility is
recommended.
Description
Keywords
Proteus,, infection,, antibiotics., Sensitivity Pattern
Citation
Giwa. A, A.A Akanbi II,A.Nyamngee, A.A.Adedoja,A.A.Njan,S.K Olubiyi, F.M Rejuaro, S.A.Iman Antibiotics Sensitivity Profile Of Proteus Species Associated With Specific Infections at University Of Ilorin Teaching Hospital, Ilorin. Tropical Journalof Health Sciences, Published by College of Health Sciences, University of Ilorin