Proteinease Inhibitory, Membrane Stabilization, Phytochemical and Antioxidant Evaluations of Leaves, Seeds and Calyces of Four Selected Edible Medicinal Plants
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Date
2017-04-07
Journal Title
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Publisher
Tailoy and Francis
Abstract
The aqueous extracts of the edible parts of four common medicinal plants
(Hibiscus sabdariffa, Telfairia occidentalis, Moringa oleifera and Ocimum gratissimum)
readily consumed as food or supplements in many African settings are examined for
some of their acclaimed pharmacological activities and possible potential associated
risks. The classes of phytochemicals present are examined qualitatively and
quantitatively, while the antioxidant activities were determined using three assays
which include 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis-3-ethylbenzothiazoline-
6-sulfonate (ABTS) and hydrogen peroxide (H2O2) assays. The anti-inflammatory
activities were also examined using proteinase inhibitory assays and red blood
cell membrane stabilisation assays. Both the antioxidant and anti-inflammatory
activities of the plants indicated that the plants have potentials for applications in
foods and nutraceuticals that can be used for the management of various ailments and diseases. However, the consumption of H. sabdariffa leaf should be highly
regulated as the extract exhibited reduced cell membrane stabilisation activities at
increased concentrations.
Description
Keywords
antioxidant, membrane-stabilisation, proteinase inhibition, Telfairia occidentalis, Moringa oleifera, Hibiscus sabdariffa