Phytochemical and antimicrobial activity of the leaves of lannea kerstingii engl & k. Krause (anacadiaceae)
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Date
2014
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Nitte University
Abstract
The phytochemical and antimicrobial activity of the petroleum ether and crude methanol extracts, chloroform and ethyl acetate
fractions of the leaves of Lannea kerstingii were investigated. Phytochemical screening revealed the presence of steroids and
triterpenes in the petroleum ether extract, steroid, triterpene, flavonoids and tannins in both crude methanol extract and chloroform
fraction while the ethyl acetate fraction contained only flavonoids and tannins. The extracts exhibited antimicrobial activities with zones
of inhibition ranging from 17.00 to 21.03, 20.10 to 25.24, 25.32 to 34.02 and 22.28 to 27.20 mm for petroleum ether extract, methanol
extract, chloroform and ethyl acetate fractions respectively. The minimum inhibitory concentration was between 5 and 10mg/ml,
5mg/ml for the petroleum ether and methanol extract respectively, and between 2.5 and 5 mg/ml, 5mg/ml for the acetate fractions.
The minimum bactericidal concentration for all the extracts was 40mg/ml respectively except for chloroform fraction which ranged
from 20 to 40mg/ml. The minimum fungicidal concentration for all the extracts was found to be 40mg/ml respectively. This result
indicates the broad spectrum antimicrobial potential of L. Kerstingii and justifies the use of this plant in traditional medicine.
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Keywords
antimicrobial, phytochemical, barteri, lannea kerstingii