Antimicrobial Activities of Vernonia amygdalina Against Oral Microbes
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Date
2012
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IDOSI Publications
Abstract
Vernonia amygdalina was assessed for active principles. The results showed that the extract of the plant possessed the active principles e.g. terpenoids, tannins, alkaloids, saponins and glycosides. The antimicrobial activity of the extracts was assayed against Streptococcus mutans and Staphylococcus aureus, using the agar diffusion method. The extract from V. amygdalina show a very high antimicrobial activity because they somehow have a very low pH value. The ethanolic extract of V. amygdalina has the lowest minimum inhibitory concentration on Streptococcus mutans at 25mg/ml while aqueous extract of
V. amygdalina had the highest value of MIC on Streptococcus mutans at 55mg/ml. The ethanolic and aqueous extract of V. amygdalina had their MIC at 60mg/ml on S. aureus which was the highest minimum inhibitory concentration on Staphylococcus aureus. Ethanolic extract of V. amygdalina had the lowest value on S. aureus at 40mg/ml. On the whole, most of the sensitive extract were only able to inhibit the growth of the organism
which is known as bacteriostatic in action while some exert a killing effect on the test organism and suggests that the extracts from plants were bactericidal.
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Keywords
Vernonia amygdalina, MIC, MBC, Streptococcus mutans, S. aureus
Citation
12