Browsing by Author "et al"

Now showing 1 - 4 of 4
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    Basic Laboratory Practicals in Microbiology
    (Department of Microbiology, University of Ilorin, Nigeria., 2017-05-12) Olayemi, A.B.,; Sani, A.,; Oyeyiola, G.P; Omojasola, P.F.; Kolawole, O.M.; Arekemase, M.O; Ahmed, R.N.; Anibijuwon, I.I.; Sule, I.O; Agbabiaka, T.O.; Adebisi, O.O; Udeze, A.O; Ahmed El-Imam, A.M; Oke, M.A; Kazeem, M.O; et al
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    Expert System and Decision Support System for Electrocardiogram Interpretation and Diagnosis: Review, Challenges and Research Directions.
    (MDPI Publishers, Basel Switzerland, 2022) Adewole, K.S.; Mojeed, H.A.; Ogunmodede, James Ayodele; Gabralla, L.A.; FARUK, N; ABDULKARIM, A; et al
    Abstract: Electrocardiography (ECG) is one of the most widely used recordings in clinical medicine. ECG deals with the recording of electrical activity that is generated by the heart through the surface of the body. The electrical activity generated by the heart is measured using electrodes that are attached to the body surface. The use of ECG in the diagnosis and management of cardiovascular disease (CVD) has been in existence for over a decade, and research in this domain has recently attracted large attention. Along this line, an expert system (ES) and decision support system (DSS) have been developed for ECG interpretation and diagnosis. However, despite the availability of a lot of literature, access to recent and more comprehensive review papers on this subject is still a challenge. This paper presents a comprehensive review of the application of ES and DSS for ECG interpretation and diagnosis. Researchers have proposed a number of features and methods for ES and DSS development that can be used to monitor a patient’s health condition through ECG recordings. In this paper, a taxonomy of the features and methods for ECG interpretation and diagnosis were presented. The significance of the features and methods, as well as their limitations, were analyzed. This review further presents interesting theoretical concepts in this domain, as well as identifies challenges and open research issues on ES and DSS development for ECG interpretation and diagnosis that require substantial research effort. In conclusion, this paper identifies important future research areas with the purpose of advancing the development of ES and DSS for ECG interpretation and diagnosis.
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    Risk Factor Characterization of Ischemic Stroke Subtypes among West Africans
    (American Heart Association, 2022) Sarfo, F.S.,; Ovbiagele, B.,; Akpa, O.M.; Akpalu, A., Wahab, K.W., Obiakpo, R.,; Ogunmodede, James Ayodele; Sule, A.G.; et al
    BACKGROUND AND PURPOSE: To identify the qualitative and quantitative contributions of conventional risk factors for occurrence of ischemic stroke and its key pathophysiologic subtypes among West Africans. METHODS: The SIREN (Stroke Investigative Research and Educational Network) is a multicenter, case-control study involving 15 sites in Ghana and Nigeria. Cases include adults aged ≥18 years with ischemic stroke who were etiologically subtyped using the A-S-C-O-D classification into atherosclerosis, small-vessel occlusion, cardiac pathology, other causes, and dissection. Controls were age- and gender-matched stroke-free adults. Detailed evaluations for vascular, lifestyle, and psychosocial factors were performed. We used conditional logistic regression to estimate adjusted odds ratios with 95% CI. RESULTS: There were 2431 ischemic stroke case and stroke-free control pairs with respective mean ages of 62.2±14.0 versus 60.9±13.7 years. There were 1024 (42.1%) small vessel occlusions, 427 (17.6%) large-artery atherosclerosis, 258 (10.6%) cardio-embolic, 3 (0.1%) carotid dissections, and 719 (29.6%) undetermined/other causes. The adjusted odds ratio (95% CI) for the 8 dominant risk factors for ischemic stroke were hypertension, 10.34 (6.91–15.45); dyslipidemia, 5.16 (3.78–7.03); diabetes, 3.44 (2.60–4.56); low green vegetable consumption, 1.89 (1.45–2.46); red meat consumption, 1.89 (1.45–2.46); cardiac disease, 1.88 (1.22–2.90); monthly income $100 or more, 1.72 (1.24–2.39); and psychosocial stress, 1.62 (1.18–2.21). Hypertension, dyslipidemia, diabetes were confluent factors shared by small-vessel, large-vessel and cardio-embolic subtypes. Stroke cases and stroke-free controls had a mean of 5.3±1.5 versus 3.2±1.0 adverse cardiometabolic risk factors respectively (P<0.0001). CONCLUSIONS: Traditional vascular risk factors demonstrate important differential effect sizes with pathophysiologic, clinical and preventative implications on the occurrence of ischemic stroke among indigenous West Africans.
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    Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa.
    (World Federation of Neurology, 2022) Okekunle, A.P.; Asowata, O.J.; FAKUNLE, A.G.; Akpa, O.M; Akpalu, A; Wahab, K.W.; Ogunmodede, James Ayodele; Olalusi, O.V.; et al
    Background: Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans. Objective: To evaluate the association of SHSE with stroke among indigenous Africans. Methods: We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05. Results: Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes. Conclusion: Culturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.