Browsing by Author "Tagoe, CNB"

Now showing 1 - 2 of 2
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    Beneficial effects of low dose Musa paradisiaca on the semen quality of male Wistar rats.
    (Nigerian Medical Journal, 2013) Alabi, AS; Omotoso, Gabriel Olaiya; Enaibe, BU; Akinola, OB; Tagoe, CNB
    Background: This study aimed at determining the effects of administration of mature green fruits of Musa paradisiaca on the semen quality of adult male Wistar rats. Materials and Methods: The animals used for the study were grouped into three: the control group, given 2 ml of double distilled water, a low dose group given 500 mg/kg/day and a high dose group given 1000 mg/kg/day of the plantain fruits, which was made into flour, and dissolved in 2 ml of double distilled water for easy oral administration. Results: Significant increment in the semen parameters was noticed in animals that received a lower dose of the plantain flour, but those animals who received the high dose had marked and very significant reduction in sperm cell concentration and percentage of morphologically normal spermatozoa. Conclusion: Musa paradisiaca should be consumed in moderate quantities in order to derive its beneficial effects of enhancing male reproductive functions.
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    Effects of unripe Musa paradisiaca on the histochemistry of the testis and testosterone levels in adult albino rats.
    (Nigerian Journal of Physiological Sciences,, 2017) Alabi, Ade Stephen; Omotoso, Gabriel Olaiya; Tagoe, CNB; Akinola, OB; Enaibe, BU
    Summary: This study was aimed at determining the effects of the unripe fruit of Musa paradisiaca on the testis and testosterone levels in male Wistar rats. The animals were grouped into three, comprising a control, and 2 treatment groups administered with different doses (500 mg/kg and 1000 mg/kg) daily of the fruit flour over 28 days. Histochemical evaluation of the testes was done using Haematoxylin and Eosin, Periodic acid Schiff’s (PAS) and Feulgen staining techniques, while the serum and homogenised testicular tissue were evaluated for testosterone levels using Accu-Bind ELISA Kit. The testis of the treated groups showed more rapidly dividing cells and more population of sperm cells compared to the control group, and also showed more positivity for Feulgen staining and PAS reaction. Both serum and testicular testosterone levels were however reduced. Serum testosterone was significantly lowered in the animals given the low dose (0.67 ± 0.03 ng/ml), compared to those given high dose (0.85 ± 0.02 ng/ml) and the control animals (1.88 ± 0.15 ng/ml) (p < 0.05). Changes in testicular testosterone were not statistically significant. The study suggests that M. paradisiaca fruit has reproductive enhancing potential when consumed moderately, but this benefit may not be related to testosterone levels.