Browsing by Author "Shodeinde, A. S."

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    Synthesis, Characterization and Antimicrobial Activity of Metal (II) Complexes of Mixed Acetylsalicylic acid and 1, 10-phenanthroline
    (Faculty of Physical Sciences, University of Ilorin, Ilorin, Nigeria, 2017-11-20) Lawala., A.; Shodeinde, A. S.; Obaleye, J. A.; Baba, A. A.
    A series of Mn(II), Fe(II), Co(II), Cu(II) and Zn(II) mixed ligands-metal complexes derived from 1,10phenanthroline (PHEN) and acetylsalicylic acid (ASP) have been synthesized. The compounds were characterized using elemental analysis, infrared, ultraviolet/visible spectroscopies and X-ray powder diffraction .The coordination of the two ligands towards the central metal ion has been proposed in the light of elemental analysis, infrared, ultraviolet/ visible, and X-ray powder diffraction spectroscopic studies. The results of the physical and spectroscopic data confirmed that the ligands are bidentate chelating agents. In 1, 10phenanthroline, coordination occurred through the two pyridinic nitrogen groups. Acetylsalicylic acid complexes coordinate through the carbonyl oxygen of the carboxyl and the ester groups. The compounds form a six- coordinate geometry. Antimicrobial activity of the mixed ligand metal complexes and the free ligands were carried out against the bacteria: Escherichia coli, staphylococcus aureus, klebsiella pneumonia, pseudomonas aeruginosa and the fungi candida spp. The mixed ligands metal complexes showed higher activities when compared to the free ligands of acetylsalicylic acid but were less active than the free 1, 10-phenanthroline ligand. The complexes of Mn (II) showed significant antimicrobial activity while the Fe (II) complex exhibited the least activity against the bacteria and fungi organisms.
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    Synthesis, Characterization and Antimicrobial activity of Mixed Transition Metal Complexes of salicylic acid with 1,10 - Phenanthroline
    (World Bank Assisted National Agricultural Research Project (NARD), Faculty of Science, University of Port-Harcourt, Nigeria, 2017) Lawal, A.; Shodeinde, A. S.; Amolegbe, S. A.; Elaigwu, S. E.; Yunus-Issa, M. T.
    A new series of Mn(II), Fe(II), Co(II), Cu(II) and Zn(II) mixed ligands-metal complexes derived from salicylic acid (SA) and 1,10-phenanthroline (PHEN) have been synthesized and characterized by spectroscopic studies. The coordination of the two ligands towards central metal ions has been proposed in the light of elemental analysis, IR, UV–vis spectroscopic studies. The results of the physical and spectroscopic data confirmed that the ligands are chelating agents. In 1, 10-phenanthroline, coordination occurred through the two pyridinic nitrogen groups, while in the salicylic acid coordination occurred through the oxygen of the hydroxyl and the carboxylic groups. All the complexes synthesized were of octahedral geometry.Antimicrobial activity of the mixed ligands metal complexes and the free ligands were carried out against the bacterial Escherichia coli, staphylococcus aureus, klebsiella pneumonia, pseudomonas aeruginosa and the fungi candida spp. The mixed ligands metal complexes showed higher activities when compared to the free ligands of salicylic acid but were less active than the free 1,10-phenanthroline ligand. The complexes of Cu (II) showed the highest antimicrobial activity while the Fe(II ) complex showed the least activity against the bacterial and fungi organisms