Browsing by Author "Saidu, Rakiya"
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Item Comparing perioperative vaginal misoprostol with intraoperative pericervical hemostatic tourniquet in reducing blood loss during abdominal myomectomy: A randomized controlled trial.(Turkish-German Gynecological Association, 2019) Afolabi, Muhibat; Ezeoke, Grace; Saidu, Rakiya; Ijaiya, Munirdeen; Adeniran, AbiodunObjective: To compare the effectiveness of perioperative vaginal misoprostol with intraoperative pericervical hemostatic tourniquet in reducing blood loss during abdominal myomectomy. Material and Methods: A randomized controlled trial involving women with uterine leiomyoma who underwent abdominal myomectomy was conducted at a tertiary facility in Nigeria. Participants were recruited after they gave informed consent and randomized into group I (single dose 400 μg vaginal misoprostol one-hour before surgery) and group II (intraoperative pericervical hemostatic tourniquet). Eighty participants (40 in each group) were recruited. Uterine size was measured in centimeters above the pubic symphysis, and blood loss estimation involved direct volume measurement and gravimetric methods. The main outcome measures were intraoperative blood loss, blood transfusion, and recourse to hysterectomy. Ethical approval and trial registration were obtained; the data were analyzed using the SPSS software version 21.0; p<0.05 was considered significant. Results: Participants in group I had higher mean intraoperative blood loss (931.89±602.13 vs 848.40±588.85 mL, p=0.532), intra-operative blood transfusion rates (60 vs 55%; p=0.651) and mean units of blood transfused (1.30±1.20 vs 1.20±1.30; p=0.722) compared with group II. The mean uterine size (19.50±6.93 vs 20.05±6.98 cm; p=0.725) and number of fibroid nodules (11.25±7.99 vs 11.45±8.22; p=0.912) were comparable. The change in post-operative hematocrit was 2.66±2.21% vs 3.24±2.85% (p=0.315) and post-operation blood transfusion was 2.5 vs 5% (p=0.556). There was no recourse to hysterectomy in either of the study groups. While adverse effects of misoprostol occurred in 5 (12.5%) participants of group I. Conclusion: The effectiveness of perioperative vaginal misoprostol is comparable to intra-operative hemostatic pericervical tourniquet in reducing blood loss during abdominal myomectomy. (J Turk Ger Gynecol Assoc 2019; 20: 23-30)Item Double-blind randomized controlled trial comparing misoprostol and oxytocin for management of the third stage of labor in a Nigerian hospital.(The Journal of the International Federation of Obstetrics and Gynaecology (FIGO), 2015) Musa, Abdulkarim; Ijaiya, Munir'deen; Saidu, Rakiya; Aboyeji, Abiodun; Jimoh, Abiodun; Adesina, Kikelomo; Abdul, IshaqObjective: To compare the efficacy of oral misoprostol with that of oxytocin for active management of the third stage of labor (AMTSL). Methods: A double-blind randomized control trial was undertaken at a center in Ilorin, Nigeria, between January and June 2013. Every other eligible patient (in the first stage of labor at term, to have a spontaneous vaginal delivery, and no/low risk of postpartum hemorrhage [PPH]) were randomly assigned with computer-generated random numbers to receive oral misoprostol (600 μg) plus placebo injection or oral placebo plus oxytocin injection (1 mL of 10 IU) in the third stage of labor. The primary outcome was amount of blood loss during delivery. Results: Mean postpartum blood loss was 325.85 ± 164.72 mL in the 100 patients givenmisoprostol and 303.95±163.33 mL in the 100 patients given oxytocin (P=0.391). PPH(≥500mL blood loss) was recorded in 15 (15.0%) patients given misoprostol and 14 (14.0%) given oxytocin (P = 0.841). Shivering, pyrexia, and diarrhea were all significantly more common in the misoprostol group (P b 0.01 for all). Conclusion: The efficacy of oral misoprostol was similar to that of intramuscular oxytocin. Adverse effects associatedwith misoprostol were transient and self-limiting. Thus, oral misoprostol is efficacious and a good alternative to oxytocin for AMTSLItem Epidemiology of severe pre-eclampsia and eclampsia in Ilorin.(Library and Publications Committee, University of Ilorin, Ilorin,, 2013) Bolaji, Benjamin olusomi; Oyedepo, olubukola Olanrewaju; Saidu, Rakiya; Aderibigbe, SA; Fawole, AA; Balogun, Olayinka Rabiu; Aboyeji, Abidun Peter; Jimoh, AbdulGaffar AG; Olawumi, Hannah O; Adebisi, SAThis study was carried out over a 10-month period in the University of Ilorin Teaching Hospital to determine the frequency and epidemiological factors of severe preeclampsia and eclampsia in Ilorin, North-central Nigeria. This was a prospective study of severely preeclamptic and eclamptic patients admitted to the labour ward of the UITH. Patients with normal pregnancies who agreed to participate were the control group. Demographic, clinical variables, maternal and foetal outcomes, and, complications were assessed. One hundred women (50 study group & 50 control group) participated in the study. Statistically significant findings among the study group included lower GA at delivery (p=0.0001), family history of hypertension (p=0.02), new partner (0.001), more interventions at delivery (p=0.000), higher number of preterm deliveries (0.000). Though 2 maternal deaths and 5 perinatal deaths were recorded in the study group, none occurred in the control group. Deeper understanding of the epidemiology of severe preeclampsia and eclampsia is very important to finding ways to further lower its contribution to maternal mortality in our societiesItem Jadelle sub-dermal implant: evaluation of acceptance, effectiveness, side effects and discontinuation in Ilorin, Nigeria(School of Medicine, Kenyatta University, Kenya, 2014) Balogun, Olayinka; Afolabi, Muibat; Adeniran, Abiodun; Saidu, RakiyaObjective: To determine the safety, efficacy, acceptability, side effects and discontinuation pattern of Jadelle® subdermal implant.Design: A retrospective descriptive study. Setting: The Family Planning Clinic of the University of Ilorin Teaching Hospital [UITH], Ilorin, Kwara State, Nigeria. Subjects: All clients who accepted Jadelle® sub-dermal implant between 1st January 2008 and 31st December 2012. Data was collected from the individual patient case files and analysed using SPSS version 20. Main outcome measures: The prevalence, efficacy, side effects and discontinuation among users of Jadelle®. Results: Of the 2,324 clients during the study period, 108 chose Jadelle® with prevalence of 4.7%. Among these acceptors, 23 (21.3%) had side-effects following insertion. The commonest side effect was menstrual irregularities (60.9%). Twelve acceptors (11.1%) discontinued before the due date for the removal of the insert. Insertion after oneyear from last childbirth (p 0.021) andtwo or more side effects (p 0.001) were significant predictors of discontinuation while previous contraceptive use, number of children alive and age were statistically insignificant. The pearl index was 0 during the study period. Conclusion: Jadelle® is an acceptable contraceptive and the side effects are tolerable to most clients in the study.Item Pattern of contraception among users in a Nigerian Public Family Planning Unit.(Sudan Medical Journal, 2016-08) Adesina, Kikelomo; Abdul, Ishaq; Olarinoye, Adebunmi; Jimoh, Abdul; Saidu, Rakiya; Ezeoke, GraceBackground: Nigeria is a developing country with high fertility rate and complications of unwanted pregnancies. Contraception is vital for fertility regulation and prevention of complications associated with unplanned pregnancy. The use of available methods depends on their acceptability by people in a community which may be determined by their social characteristics. To determine the uptake of modern contraceptive methods among women seeking family planning services in a Nigerian Tertiary Hospital and document the acceptability of methods by new clients. Materials and Methods: A retrospective review of contraceptive users that attended the family planning clinic of the University of Ilorin Teaching Hospital, Ilorin, between January 2000 and December 2009 was done Data on socio-demographic characteristics, previous method(s) of contraception, duration of use, reasons for discontinuation, side effects and reasons for current contraceptive choices were obtained from the documented case notes. Old and new users were compared. Statistical analysis used was descriptive and inferential statistics. Results: Five thousand, five hundred and three clients' records were reviewed, 59.8% of all attendees were new acceptors of modern contraceptive methods in the facility. The percentage of new acceptors per year was 31.7-51.9%. Intrauterine contraceptive device (IUCD) was the commonest method among the new and old clients and most of them required contraception for child spacing rather than completion of family size (P<0.001).Bilateral Tubal Ligation and condom were the least common methods (0.1% respectively). Most of the new clients (67%) were referred by health personnel. In conclusion, the acceptability of modern contraceptive methods by new clients at U.I.T.H between 2001 and 2009 was high. IUCD was the commonest method chosen. Use of surgical contraception was low.