Browsing by Author "Saidu, Rakiyat"

Now showing 1 - 3 of 3
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    Partner disclosure and human immunodefficiency virus serology status among antenatal clinicattendees with human immunodefficiency virus infection in Ilorin
    (College of Medicine and Health Sciences, Abia State University and Abia State University Medical Research Society, 2014-07) Adeniran, Abiodun; Raji, Sekinat; Saidu, Rakiyat; Omokanye, Lukman
    Background: The high prevalence of human immunodefi ciency virus (HIV) remains rampant in sub-Saharan Africa with poor partner disclosure and a high risk for infections among serodiscordant couples. Objective: To determine the prevalence, partner disclosure and HIV serology pattern among HIV positive antenatal clinic attendees. Design: A descriptive (retrospective) study. Setting: The antenatal clinic of a tertiary center in Ilorin, Nigeria. Subjects: HIV positive women receiving antenatal care at the study site from September 1, 2010 to February 28, 2013. Materials and Methods: The case fi les and the antenatal clinic records of all participants were retrieved, relevant data were extracted and presented in tables and charts. Results: Of the 7,342 antenatal clinic attendees during the study period, 237 were HIV-positive (prevalence 4.9%). The modal age group was 30–34 years (42.6%), adolescents were three (1.3%), 206 (86.9%) were educated, 192 (81%) were employed, 96 (40.5%) were diagnosed during index pregnancy while 141 (59.5%) were diagnosed and commenced antiretroviral therapy prior to conception. The modal age for male partners was 35–44 years (54%), 228 (96.2%) were aware of the woman’s HIV status, 211 (89%) of these men were aware of their own HIV status while the 26 (11%) refused testing; the serodiscordance rate was 56.7%. Conclusion: The high serodiscordance rate for HIV infection portends a signifi cant risk for transmission between partners; thus, higher awareness during and outside pregnancy should be improved upon to educate on strategies for preventing partner and mother to child transmissions.
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    Pregnancy outcomes in booked HIV positive women initiating highly active antiretroviral therapy
    (School of Medicine and Health Sciences, University forDevelopment Studies, Tamale, Ghana, 2014) Adeniran, Abiodun; Afolabi, Muibat; Saidu, Rakiyat
    Pregnancy outcomes in HIV positive women remain a concern especially in sub-Saharan Africa which bears the highest burden of the disease. To evaluate pregnancy outcomes in booked preg-nant women on Highly Active Antiretroviral Therapy (HAART) at the University of Ilorin Teach-ing Hospital (UITH), Ilorin, Nigeria; a case control study (with women initiating HAART in preg-nancy as subjects and those who initiated it before pregnancy as control) of 268 HIV-positive wom-en managed between March 2009 and February 2013 was undertaken at the hospital. Inclusion cri-teria comprised HIV-positivity, booking, antenatal care and delivery at the study site. From the total of 8,958 women who had antenatal care during the period, 502 had HIV infection (prevalence 5.6%) out of which 268 satisfied the inclusion criteria and were enrolled into the study. Subjects were 54(20.2%) while 214(79.8%) were controls; the mean age of participants was 31.0±4.5 years while mean parity was 2.0±1.5. Pregnancy outcomes were worse in subjects with statistical signifi-cance in miscarriage (11.1% vs. 0.9%; OR 11.78, 95% CI 2.07-87.03, p <0.01), preterm delivery (31.5% vs. 1.9%; OR 24.35, 95% CI 7.15-91.26, p<0.01), term pregnancy (42.6% vs. 96.3%; OR 0.03, 95% CI 0.01-0.08, p<0.01), birth asphyxia (OR 8.31, 95% CI 3.25-21.45 p<0.01), low birth weight babies (OR 260.0, 95% CI 66.51-1142.77, p<0.01) and maternal puerperal complications (anaemia 35.2% vs. 0.9%; OR 68.79, 95% CI 14.28-452.19, p <0.01). Mother to child transmission of HIV was recorded in only 3(1.1%) babies among the subjects. Commencement of HAART before pregnancy appears to improve pregnancy outcomes in HIV positive women.
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    Role of risk-based approach in the prevention of vertical transmission of neonatal sepsis
    (National Postgraduate Medical College of Nigeria, 2015-06) Adeniran, Abiodun; Aboyeji, Peter; Fawole, Adegboyega; Adesiyun, Omotayo; Saidu, Rakiyat
    Aims and Objectives: Vertical transmission of infections remains a common cause of neonatal morbidity and mortality worldwide. We studied the risk-based approach in preventing the vertical transmission of neonatal sepsis. Patients and methods: A prospective case control study of 154 pregnant women with risk factors for vertical transmission of infections (subjects) and 154 pregnant women without the risk factors (control) at University of Ilorin Teaching Hospital, Ilorin from 1st July to 31st December, 2010. After counseling and consent taking, all participants had active management of labour and all subjects had parenteral intrapartum antibiotic prophylaxis with Ampicillin. There was postnatal evaluation of all babies for signs of neonatal sepsis followed by blood culture and treatment of culture positive babies. The outcome measures were signs and symptoms of neonatal sepsis, neonatal positive blood culture and maternal postpartum morbidity. Results: Neonatal sepsis occurred in 16 babies (subjects=11, control=5); three babies had Early Onset Group B Streptococcal Disease (EOGBSD) (subjects=2, control=1; P=0.501) while 13 had non Group B Streptococcal (GBS) infections (subjects=9, control=4; P=0.113); onset of signs and symptoms was <24hrs in all cases, incidence of EOGBSD were 12.9/1000 (subjects) and 6.5/1000 (controls). Subjects whose babies had sepsis had multiple risk factors; one dose of antibiotics and antibiotics to delivery interval <2hours. There was no sepsis in babies of mothers who had adequate antibiotic prophylaxis. There was no maternal or neonatal death but 17.5% of subjects had maternal postpartum morbidities. Conclusion: The risk-based approach is a practicable alternative in preventing vertical transmission of neonatal sepsis if antibiotic prophylaxis is adequate before delivery.