Browsing by Author "S.B. Kareem,"

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    Centre journals
    (Centrepoint Journal, 2015) M.S. Ajao,; A. Imam,; M.Y. Adana,; S.B. Kareem,; A.S. Alabi,; A. Olawepo, A; A.A. Okesina,; R.E. Kadir,; A.O Oyewopo
    The study was designed to compare the effects of Rauwolfia vomitoria and chlorpromazine on metabolic activities, spatial memory performance, central cholinergic markers, oxidative stress markers and neurohistoarchitecture in the brain of adult wistar rats. Twenty five adult male wister rats weighing between 200 - 230 g were divided into five groups (A-E) of five rats each. Group A (control) received 2mls of normal saline daily, Group B received 5mg/kg of chlorpromazine, Group C received 10 mg/kg of chlorpromazine, Group D received 150 mg/kg of R. vomitoria and Group E received 300 mg/kg of R. vomitoria orally. All the medications were given daily for 21 days. Body weights were taken weekly and recorded. A y-maze apparatus was used to assess the spatial memory performance in the rats at days 14 and 21 of the experiment. All the animals were euthanized using 20mg/kgbw of intramuscular ketamine, cardially perfused with 4% paraformaldehyde and the brains were removed, some were homogenised for analysis of central cholinergic markers and others for histological analysis. Low doses of chlorpromazine increase body weight and Rauwolfia vomitoria increase central cholinergic markers. The findings of the study show that R.vomitoria and chlorpromazine exert differential and dosage dependent effects on body weight, central cholinergic neurons and learning performance. The conclusion from the study indicates that R. vomitoria could be a better alternative drug in the treatment of psychosis with lesser metabolic and central nervous system side effects.
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    Facial Anthropometry And Sex Discriminatory Characteristics Among University Of Ilorin Students
    (College of Health Sciences, University of Ilorin, Ilorin, Nigeria, 2019-04) A.S.Alabi; B.T. Oladimeji,; S.B. Kareem,; F.S.Lewu,; A.T. Atoyebi,; K.A. Akintunde,; R.S.Opayemi
    Prediction of sex from different dimensions has considerable forensic value, not only for the identification of human remains but also in estimating sex from evidence at disaster sites and in corroborating reports from scientists. This study investigated the facial parameters and sexual dimorphism among University of Ilorin students. A total of 376 students consisting office major divisions in a university setting (sciences, social sciences, health sciences, technology and humanities) were used in the study. Standard anthropometric methods were used to measure facial height (LFH) and Bizygomatic Width (BZW) from a frontal repose photograph. Six different facial parameters were calculated. Data was analyzed using SPSS version 23statistical software. Confidence level was set at 95%; as p-values ≤ 0.05 were considered significant. Discriminant function analysis, mean standard deviation of mean and chi-square of the studied population were presented with P<0.05. For LFH in both sexes, significant value of 0.010 was recorded indicating a statistically significant difference. For BZW in both sexes, a significant value of 0.039 was recorded also indicating a statistically significant difference. For TFH in both sexes, 0.039 value was recorded also indicating a statistically significant difference in the measured facial parameters. UFH, MFH and F.I were found to be non-significant with recorded values of 0.077,0.082 and 0.277 respectively. The p-value recorded for this non significant values weregreaterthan0.05(P>0.05). The findings from this study clearly showed sex-associated difference in facial parameters but argue that a single set of facial parameters may not be applicable in sex grouping. Therefore, facial parameter scan serve as adjunct in sex differentiation.