Browsing by Author "Owolabi, Omolola"
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Item Hepatitis C Virus (HCV) Seroprevalence, Antigenaemia and associated risk factors among pregnant women in Nigeria.(Ethiopian Medical Association, Ethiopia, 2015) Owolabi, Omolola; Adesina, Kikelomo; Fadeyi, Abayomi; Popoola, GbengaBackground & Aims: Hepatitis C viral infection is a significant public health challenge with potential risk of progressing to liver cirrhosis and hepatocellular carcinoma (HCC). Actively infected mothers can transmit the virus to their babies who may develop liver cirrhosis and HCC as young adults. We determined the seroprevalence of HCV, its antigenaemia and associated risk factors among pregnant women. Methods: We recruited 400 pregnant women and tested their serum for HCV antibodies using immunechromatographic test and determined the HCV core antigenaemia among HCV sero-positives by enzyme-immunoassay (EIA). The bio-socio-demographic variables of the participants were statistically correlated to the test results. Results: Seroprevalence of HCV was 5.8% (23/400) and the prevalence of HCV core antigenaemia was 73.9% (17/23). None of the bio-socio-demographic variables of the participants and other known risk factors evaluated had significant influence on either seroprevalence of HCV or its antigenaemia. Only the employment status of the participants’ husbands (p=0.01) significantly affected seropositivity of HCV. Conclusion: HCV core antigenaemia is high among pregnant women who have antibodies to HCV in our environment and this signifies an active hepatitis C virus infection.Item Role of Mid Trimester Cervical Parameters in Predicting Pregnancy Outcome(SOGON, 2016) Adesina, Kikelomo; Owolabi, Omolola; Owolabi, James; Oguntoyinbo, Adewale; Olarinoye, Adebunmi; Aboyeji, Abiodun; Fawole, AdegboyegaTo determine the cervical length and internal Os diameter at mid trimester in a low risk population for preterm delivery and pregnancy outcome.Item Transvaginal sonographic parameters of the cervix in low risk pregnancies in Ilorin.(west African medical ultrasound society., 2017) Adesina, Kikelomo; Owolabi, Omolola; Oguntoyinbo, Adewale; Owolabi, James; Aboyeji, Abiodun; Olarinoye, AdebunmiTo determine values of mid pregnancy cervical length and internal ostial diameter in a low risk population and correlate measurements with parity and gravidity. A cross sectional study of booked pregnant women at gestational age of 20 – 24 weeks with viable singleton pregnancy. Women with multiple pregnancies, cervical incompetence, cervical cerclage, previous history of cervical surgery, previous myomectomy, caesarean section scars, vaginal bleeding/low lying placenta, medical disorders in pregnancy were excluded. The transvaginal ultrasound scanning was performed with Aloka ultrasound machine at the frequency of 7.5MHz. The lubricated probe was inserted gently to a depth of 2-3 inches into the vagina. Cervical length was measured as distance between the internal and external cervical ostia along the endocervical canal. Internal Os was defined as the level where the cervical canal meets with the amniotic sac. Data were analyzed using Statistical Package for Social Sciences (SPSS) software package version 20. The results were expressed with descriptive statistics. P value of <0.05 was taken as significant. Percentiles, Pearson and Spearsman correlation tests were calculated and used. There were 159 participants. The mean age of the participants was 29.58±4.64 years and a range of 15- 39 years, primigravida were 37.7%, 57.2% w e r e m u l t i g r a v i d a s w h i l e ( 5 % ) w e r e grandmultiparous. The mean cervical length of the population was 39.72 ± 6.81mm and the range 25.00- 62.00mm.The mean Internal Os diameter was 3.06 ± 0.74 mm, range of 2.00- 5.00mm.In the study population 18.9% had internal Os diameter of < 3mm while 81.1% had internal Os diameter of 3-5 mm. The mean cervical length at 5th, 10th, 25th, 50th, 75th, 90th and 95th percentiles were 31mm, 32mm, 35mm, 39mm, 44mm 49mm and 52.00 mm respectively. Correlations between parity, gravidity and cervical parameters were not statistically significant as well as the relationship between cervical length and internal os diameter. The mean values of cervical length and internal os diameter at 20-24 weeks in singleton pregnancy with low risk for preterm delivery were found to be 39.72 ± 6.81mm and 3.06 ± 0.74 mm respectively. There was no significant correlation between the cervical parameters, parity and gravidity.