Browsing by Author "Omotoso, AB"
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Item Benefits, disadvantages and challenges of virtual conferencing in the COVID-19 era: Adjusting to the new normal(College of Health Sciences, Osun State University, 2022-02-17) Ogunmodede, JA; Ogunmodede, AJ; Buhari, OIN; Dele-Ojo, BF; Omotoso, AB; Agede, OA; Omotoso, ABOObjective: The COVID-19 pandemic has had tremendous effect on the medical and scientific community. Measures instituted to curb the spread of the disease such as physical distancing and ban on large gatherings have significantly altered conferencing activities of medical professional associations. With no end in sight to the pandemic, it is certain that medical professional associations may have to make do with purely virtual or hybrid conferencing for some time to come. The objective of this paper is to highlight the benefits, disadvantages and challenges of virtual conferencing Methods: We searched Pubmed, Embase, Scopus, and AJOL databases from January 1, 2021 to December 31, 2021 for publications describing the benefits, disadvantages and challenges of virtual conferencing during the pandemic. This, together with authors' experience formed the resource base for this work. Conclusion: We propose ways the scientific community in Nigeria can maximize the virtual conferencing while the pandemic lasts. We also advocate increased discussion about how to improve the virtual conferencing culture and the development of guidelines for purely virtual or hybrid scientific conferencesItem Relationship between CD4 count, Neutrophil-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio and Left Ventricular Systolic Function in HIV/AIDS Patients(East African Medical Association, 2023-01-10) Ogunmodede, JA; Agede, OA; Dele-Ojo, BF; Adeoye, AJ; Ogunmodede, AJ; Omotoso, ABBackground: Inflammation is a cardinal feature of Human Immunodeficiency Virus (HIV) infection and accounts for most of its clinical manifestations. Cardiovascular involvement is common in HIV. Haematologic inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are elevated in some cardiovascular diseases in the non-HIV population. CD4 count correlates with left ventricular size. The relationship between haematologic inflammatory markers NLR and PLR and left ventricular (LV) systolic function and their prognostic value is not well studied in HIV patients. Objective: To determine the relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value as surrogates for the occurrence of LV systolic dysfunction (LVSD) Design: Cross-sectional Setting: The Cardiology unit of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria Participants: 150 HIV positive patients Outcome measures: The relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value for the occurrence of LV systolic dysfunction (LVSD) Results: The mean age was 37.14+8.6 years, 86 (64%) female, median duration of illness 6(0.94-24) months. NLR and PLR had a negative correlation with LV EF, the CD4 count had positive correlation. On multivariate analysis only PLR was predictive of EF. A cut-off PLR of 169.5 was only weakly discriminatory of LVSD with sensitivity of 81.3% and specificity of 72.9%, AUC 0.794. Conclusion: CD4 count, and inflammatory markers correlate with LVEF in HIV patients. Only PLR was predictive, its value as a diagnostic surrogate for LVSD needs further investigationItem Relationship between CD4 count, Neutrophil-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio and Left Ventricular Systolic Function in HIV/AIDS Patients(East African Medical Association, 2023) Ogunmodede, JA; Agede, OA; Dele-Ojo, BF; Adeoye, OG; Ogunmodede, AJ; Omotoso, ABBackground: Inflammation is a cardinal feature of Human Immunodeficiency Virus (HIV) infection and accounts for most of its clinical manifestations. Cardiovascular involvement is common in HIV. Haematologic inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are elevated in some cardiovascular diseases in the non-HIV population. CD4 count correlates with left ventricular size. The relationship between haematologic inflammatory markers NLR and PLR and left ventricular (LV) systolic function and their prognostic value is not well studied in HIV patients. Objective: To determine the relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value as surrogates for the occurrence of LV systolic dysfunction (LVSD) Design: Cross-sectional Setting: The Cardiology unit of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria Participants: 150 HIV positive patients Outcome measures: The relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value for the occurrence of LV systolic dysfunction (LVSD) Results: The mean age was 37.14+8.6 years, 86 (64%) female, median duration of illness 6(0.94-24) months. NLR and PLR had a negative correlation with LV EF, the CD4 count had positive correlation. On multivariate analysis only PLR was predictive of EF. A cut-off PLR of 169.5 was only weakly discriminatory of LVSD with sensitivity of 81.3% and specificity of 72.9%, AUC 0.794. Conclusion: CD4 count, and inflammatory markers correlate with LVEF in HIV patients. Only PLR was predictive, its value as a diagnostic surrogate for LVSD needs further investigation.