Browsing by Author "Ologe, MO"

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    Effect of Management on the profile of serum electrolytes, urea and creatinine in children with Nephrotic Syndrome and Acute Glomerulonephritis in Ilorin
    (College of Health Sciences, University of Ilorin, Ilorin, Nigeria, 2006) Adedoyin, OT; Anigilaje, EA; Ologe, MO; Adeniyi, A
    Primary nephrotic syndrome (NS) and acute glomerulonephritis (AGN) are known to cause varying degrees of renal insufficiency depending on the severity. Certain drugs and management strategies used in these two disorders also have profound effect on the serum electrolyte and urea profiles. This study determines the effect of management on the profile of serum electrolytes, urea and creatinine in children with NS and AGN. A retrospective analysis of the biochemical profiles of children admitted with a diagnosis of NS and AGN between 1996 and 2004 was carried out. A total of 21 and 16 children with AGN and NS respectively met the study criteria. There was no significant difference in the serum sodium, potassium and urea in both groups during the study except at the 4th week. The prevalence of hypokalemia in both groups of children was low. The serum sodium and potassium were significantly low compared to those with AGN in the 4th week, while the serum urea and creatinine was higher in NS patients in the same period. There was also generally a low prevalence of hypokalemia throughout the study period. While the study may have confirmed the occurrence of electrolyte imbalance following the use of diuretics, it has also shown that the prevalence of such electrolyte imbalance in the first 4 weeks of treatment is rather low and insignificant despite using significant dose of the drug.
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    Pattern of Antimalarial Prescriptions for children and pregnant mothers by Private Medical Practitioners in Ilorin, Nigeria
    (Sage Publishers for Royal Society of Medicine, 2007) Ologe, MO; Mokuolu, OA; Adedoyin, OT
    A survey of the prescription practices of private medical practitioners (PMPs) in four local government areas in Kwara State, Nigeria, was carried out using a selfadministered pre-tested questionnaire. A total of 49 respondents from 40 private health facilities participated in the survey.The prescription practice of a significant number of PMPs was not in conformity with the National MalarialTreatment policy.There was inadequate knowledge of the classification of malaria; hence, many of the respondents could not recognize severe malaria. Regular continuing medical education and distribution of information, education and communication materials on malaria to private health facilities are strongly recommended
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    Prescription Pattern at a Secondary Health Care Facility in Ilorin, Nigeria
    (African Medical Sciences Research Society, Sokoto, 2007) Akande, TM; Ologe, MO
    Background/Objectives: Expenditures due to irrational use of drugs have been a strain on the meagre health budgets of several developing countries and inappropriate prescribing has been identified in many health facilities in developing countries. This study examines the prescription pattern in a secondary health facility. Method: A descriptive cross-sectional survey was used in this study. Three hundred and three randomly selected prescriptions issued to patients attending out-patients' clinics in the facility over a period of three months were examined. Data obtained was analyzed using EPI-INFO 2000 computer software. Results: Mean number of drugs per prescription in the health facility is 3.99 ± 1.55. At least 4 drugs were prescribed in 61.6% of the prescriptions. Generic prescribing was generally low. Out of a total of 1219 drugs prescribed 511 (41.9%) were prescribed in generic names. Analgesics, antimalarials, antibiotics and antihypertensives accounted for 19.7%, 10.2%, 13.0% and 4.9% of the drugs prescribed respectively. Only 124 (40.9%) of the prescriptions had all drugs prescribed available in the health facility. Conclusion: This study found practice of polypharmacy prevalent as found in other studies in developing countries among prescribers and prescription in generic names is low. Regular orientation and re-orientation of prescribers on rational drug prescription and prescription in generic names in conformity with national drug policies is necessary.