Browsing by Author "Olawumi, Hannah O."

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    An Evaluation of Inflammatory and Nutritional Status of Breast Cancer Outpatients in a Tertiary Hospital in Nigeria
    (Journal of Nutrition and Cancer., 2021-01-07) Izuegbuna, Ogochukwu O.; Olawumi, Hannah O.; Olatoke, Samuel A.; Durotoye, Idayat
    Aim: To assess the relationship between nutritional status and inflammatory markers of breast cancer patients, and to identify predictors of malnutrition in these patients. Methods: This is a cross-sectional study of 45 patients with breast cancer assessed between January and June 2018. Nutritional status was evaluated by objective and subject- ive methods. The inflammatory markers and inflammation-based scores evaluated were C- reactive protein (CRP), albumin, erythrocyte sedimentation rate (ESR), Glasgow Prognostic Score (GPS), CRP/albumin ratio, and Albumin/CRP ratio. Results: A total of 45 patients were evaluated. Majority of the patients have high levels of both CRP and ESR (73.3% and 86.7% respectively). More than 70% of the patients were well nourished. There was no significant association between CRP (P¼0.067), ESR (P¼0.094) and SGA (Subjective Global Assessment) categories. Albumin (P<0.001), Albumin/CRP ratio (P¼0.002), CRP/albumin ratio (P ¼ < 0.001), and GPS (P<0.001) were significantly associ- ated with SGA categories. On multivariate analysis, albumin (P<0.001), Albumin/CRP ratio (P¼0.004), CRP/albumin ratio (P¼0.009), GPS (P¼0.01), and ECOG (P¼0.009) were the only markers independently related to malnutrition. Conclusion: The inflammation-based scores were significantly associated with malnutrition and can be used as biochemical nutritional assessment tools in cancer patients.