Browsing by Author "Olatunji, PO"
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Item Bacterial pneumonia in AIDS patients(West African Journal of Medicine, 2006) Salami, AK; Olatunji, PO; Oluboyo, PO; Akanbi II, AA; Fawibe, EAItem EFFECT OF HIGHLY ACTIVE ANTlRETROVIRAL THERAPY ON CD4 COUNT AND WEIGHT IN AIDS PATIENTS SEEN AT THE UITH, ILORlN(Nigerian Journal of Clinical Practice, 2008-12) Olawumi, HO; Olatunji, PO; Salami, AK; Odeigah, L; Iseniyi, JOObjective: To determine the response on treatment-naive HIV/AIDS patients to the Highly Active Antiretroviral Therapy (HAART) in terms of CD4 Count and Weight gain over a period of 21'2 years. Methods: Patients with Acquired Immunodeficiency Syndrome (AIDS) were recruited under the Federal Government Highly Active Antiretroviral Therapy (HAART) programme at the University of Ilorin Teaching Hospital. The treatment regimen included Lamivudine, Starvudine and Nevirapine. The patients' responses were evaluated with respect to CD4 count and weight over the period of treatment. The diagnosis of HIVIAIDS was made on the basis of reactivity with two different ELlSAreagents, and CD4 count was done with Dynal T4 Quant method. The weights (kg.) of the patients were taken at monthly visit. Results: The duration of treatment for the patients analysed ranged from 1 month to 14 months. Analysis of CD4 count was possible in 105 patients. The mean post treatment CD4 count and weight were significantly higher than the pre-treatment values ep < 0.001 and p < 1.0I) respectively. There were significant positive correlations (p < 0.05 and p < 0.001) between increases in CD4 count and weight respectively, and duration of treatment. In eight (8) patients, CD4 Count reduced or remained the same in spite oftreatmcnt. Conclusion: The HAART regime is associated with increase in CD4 Count and weight gain. While increases in CD4 Count and weight correlated with duration of therapy, there was no correlation between CD4 Count increase and weight gain.Item Influence of highly active antiretroviral therapy (HAART) on the survival of HIV – infected patients: part report of the Ilorin trial center(2005-01) Salami, AK; Olatunji, PO; Fawibe, AE; Oluboyo, PO