Browsing by Author "Olarinoye, J. K."

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    Performance of American Diabetes Association Questionnaire for the risk and diagnosis of diabetes in hypertensive subjects
    (AACE, Nigeria Chapter, 2008) Adamu, A. N.; Ohwovoriole, A. E.; Olarinoye, J. K.; Fasanmade, O. A.; Ekpebegh, C. O.; Oyeyemi, G. M.
    The objective of the paper is to evaluate the performance of the American Diabetes Association Questionnaire for the risk/diagnosis of diabetes among subjects with systemic hypertension. Between January and May 2004, screening for type 2 diabetes was conducted among people known to have, systemic hypertension and who were regular attendees of Cardiology and Nephrology clinic of the Lagos University Teaching Hospital. Screening was done using the American Diabetes Association Questionnaire (ADAQ): take the test known the risk. Oral glucose tolerance test was carried out on all the subjects as the standard for the diagnosis of diabetes. Subjects were classified based on their total score on the ADAQ into- No Risk (where score was 0-2), High Risk (where score was 5-9) and diabetes when score was >10. Resalts: A total of 207 patients were recruited of whom l3lcompleted the study, giving a participation rate of 63.28 percent. Over thirty percent (30.53%) of the 131 subjects who completed the study were at high risk for diabetes while 69.46% were classified as Diabetes (>10) based on ADAQ. ADAQ yielded a sensitivity of 79.16%, a specificity of 32.71% a positive predictive value of 20.88% a negative predictive value of 87.5% and an efficiency of 41.22%. r = 0.04, y = 156.89+1.4 ADAQ with p value not significant (P value > 0.05) Conclusion: The ADAQ performed poorly in our cohort of patients with systemic hypertension. Modification will need to be made to the ADAQ to enhance its performance in our study population.
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    The Value of HbA1c that gives a good yield for Screening
    (Devon Science Publication, 2009) Adamu, A. N.; Ohwovoriole, A. E.; Olarinoye, J. K.; Fasanmade, O. A.; Ekpebegh, C. O.; Oyeyemi, G. M.
    HbAlc is being used as a screening toot for diabetes with its performance varying in different studies depending on the cut-off point of HbA1c used and the reference gold standard. To determine the level of HbA1c that defines the best cut-off point compatible with maximum yield using 2hours post 75gram glucose as reference. A cross sectional study of 207 patients with systematic hypertension attending the renal and cardiology out patient clinics of the Lagos University Teaching Hospital were recruited. One hundred and thirty one (131) of the subjects had OGTT done. A random sampling method was to select one out of every four who had HbAlc done using DCA 2000r autoanalyzer. Receiver Operating Characteristic Curve was plotted to determine the appropriate HbAlc cut-off point that gave optimal sensitivity and specificity for the diagnosis of diabetes using plasma venous glucose, 2 hours post 75gram OGTT. A 2x2 table was utilized to determine the predictive value, and efficiency of the HbA1c cut-off point for the diagnosis of diabetes. HbA1c cut-off point of 6.7% was found to give sensitivity of 57.14%, specificity of 75%, positive predictive value of 36.36%, negative predictive value of 85% and efficiency of 67.74%, the new cut-off point of HbA1c has improved the performance of the method as a screening tool.