Browsing by Author "Obateru, Olusegun A"

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    Colonoscopic examination of rectal bleeding in children: A report of two cases.
    (The Association of Paediatric Surgeons of Nigeria and the Pan-African Paediatric Surgical Association, 2012) Olokoba, Abdulfatai Bamidele; Obateru, Olusegun A; Bojuwoye, Matthew Olumuyiwa; Ibrahim, O.O.K.; Babalola, O.M
    Rectal bleeding in children is a frightening and cause of great concern, and of parental anxiety. In this report, we present the value of colonoscopy to unravel the diagnostic conundrum often associated with rectal bleeding in children.
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    Helicobacter pylori eradication therapy: A review of current trends
    (Nigerian Medical Association, 2013-01) Olokoba, Abdulfatai Bamidele; Obateru, Olusegun A; Bojuwoye, Matthew Olumuyiwa
    Helicobacter pylori has been implicated in the formation of chronic gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer. Eradication of H. Pylori has been recommended as treatment and prevention for these complications. This review is based on a search of Medline, the Cochrane Database of Systemic Reviews, and citation lists of relevant publications. Subject heading and key words used include H. Pylori, current treatment and emerging therapy. Only articles in English were included. There has been a substantial decline in the H. pylori eradication rates over the years, despite the use of proton pump inhibitor and bismuth salts for triple and quadruple therapies respectively. The reasons for eradication failure are diverse, among them, antibiotic resistance is an important factor in the treatment failure. Primary resistance to clarithromycin or metronidazole significantly affects the efficacy of eradication therapy. This has led to the introduction of second line, third line “rescue,” and sequential therapies for resistant cases. Subsequently, new antibiotic combinations with proton-pump inhibitors and bismuth salts are being studied in the last decade, to find out the antibiotics that are capable of increasing the eradication rates. Some of these antibiotics include Levofloxacin, Doxycycline, Rifaximin, Rifampicin, Furazolidone based therapies. Studies are ongoing to determine the efficacy of Lactoferrin based therapy.
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    Hepatocellular Carcinoma - A Synopsis Of Current Developments
    (College of Health Sciences, University of Ilorin, Ilorin, 2017-10) Olokoba, Abdulfatai Bamidele; Obateru, Olusegun A; Bojuwoye, Matthew Olumuyiwa; Olokoba, Lateefat B.
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    Indications and findings at colonoscopy in Ilorin, Nigeria
    (Nigerian Medical Association, 2013) Olokoba, Abdulfatai Bamidele; Obateru, Olusegun A; Bojuwoye, Matthew Olumuyiwa; Olatoke, Samuel Adegboyega; Bolarinwa, Oladimeji Akeem; Olokoba, Lateefat Bukola
    Background: Colonoscopy is a safe and effective means of visual inspection of the large bowel from the distal rectum to the caecum. It may be carried out for diagnostic and or therapeutic reasons. There is a paucity of data on this procedure in Nigeria. We, therefore, determined the indications, findings, and diagnostic yield in Nigerians at colonoscopy. Materials and Methods: This was a hospital-based cross-sectional study carried out at the Endoscopy unit of Crescent hospital, Ilorin from January 2010 to May, 2012. The endoscopy register was reviewed, and the biodata, indications and colonoscopic findings were recorded on a pro forma. Results: A total of 103 patients had colonoscopy. Seventy (68.0%) were males while 33 (32.0%) were females. The indications for colonoscopy were rectal bleeding 41 (39.8%), suspected colon cancer 32 (31.1%), chronic constipation and chronic diarrhoea nine each (8.7%), abdominal/anal pain five (4.9%), suspected anorectal cancer and enterocutaneous fistula two each (1.9%), faecal incontinence, occult gastrointestinal bleeding, post-colostomy for Hirschsprung disease one each (1.0%). Endoscopic findings were normal findings 21 (20.4%), diverticulosis 17 (16.5%), polyps 16 (15.5%), haemorrhoids 16 (15.5%), anorectal cancer 13 (12.6%), angiodysplasia 12 (11.7%), colon cancer eight (7.8%), colitis 7 (6.8%), anorectal ulcer 4 (3.9%), anal warts two (1.9%), anal fissure, caecal tumour, faecal impaction and proctitis one each (1.0%). The diagnostic yield was 79.6%. Conclusions: The commonest indication for colonoscopy was rectal bleeding, while the most frequent pathology was diverticulosis. The diagnostic yield was high.
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    That dyspepsia in the young could be cancer
    (Nigerian Medical Association, 2013) Olokoba, Abdulfatai Bamidele; Obateru, Olusegun A; Bojuwoye, Matthew Olumuyiwa; Ibrahim, Olatunde Kazeem; Olokoba, Lateefat Bukola
    Malignant tumour of the stomach is not common in young adults. When it does occur, it is associated with a high morbidity and mortality. The objective of this report is to document our experience with three cases of gastric adenocarcinoma in young adult Nigerians seen over a period of 18 months in our centre.