Browsing by Author "Mosam, A."
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Item Atopic dermatitis in South African children: experience from a tertiary-care centre(South African Medical Association, 2020) Katibi, O. S.; Dlova, N. C.; Chateau, A. V.; Mosam, A.Background. Atopic dermatitis (AD) is a chronic, pruritic condition with significant morbidity and some variation in clinical characteristics across different populations. Objectives. To describe the characteristics and management of AD in a paediatric cohort. Methods. A cross-sectional, descriptive study of paediatric AD patients attending the skin clinic at the King Edward VIII Hospital in Durban, South Africa, is described. Results. The observed prevalence of AD was 60.1%. A preponderance of male patients (55.6%) was seen across the cohort. An onset of AD by 1 year of age was reported in more than half (53.5%) of the patients. Slightly more than a third of the patients presented with severe disease, as determined by affected body surface area (≥50%). The head, neck and limbs were the most involved areas. Eczema herpeticum was the most common co-existing dermatosis (2.4%). Bleach baths (2%), wet wrap therapy (3.6%) and systemic immunosuppressants (4.8%) were used in the management of recalcitrant cases. Conclusion. The observed prevalence of AD is one of the highest documented among paediatric skin diseases in hospital-based studies in Africa. Predominance in children of preschool age, onset of disease by the age of 5 years, co-existing eczema herpeticum and recalcitrant disease requiring systemic immunosuppressants are consistent with trends in patients from European or Asian descent, while the level of severe disease and head and neck involvement are more consistent with reports from Africa. Further studies in a local context are needed to better understand the disease and its presentation in different populationsItem The prevalence of paediatric skin conditions at a dermatology clinic in KwaZulu-Natal Province over a 3-month period(South African Medical Association, 2016) Katibi, O. S.; Dlova, N. C.; Chateau, A. V.; Mosam, A.Background. Skin conditions are common in children, and studying their spectrum in a tertiary dermatology clinic will assist in quantifying skin diseases associated with greatest burden. Objective. To investigate the spectrum and characteristics of paediatric skin disorders referred to a tertiary dermatology clinic in Durban, KwaZulu-Natal (KZN) Province, South Africa. Methods. A cross-sectional study of children attending the dermatology clinic at King Edward VIII Hospital, KZN, was carried out over 3 months. Relevant demographic information and clinical history pertaining to the skin conditions were recorded and diagnoses were made by specialist dermatologists. Data were analysed with EPI Info 2007 (USA). Results. !ere were 419 children included in the study; 222 (53%) were males and 197 (47%) were females. A total of 64 diagnosed skin conditions were classi%ed into 16 categories. !e most prevalent conditions by category were dermatitis (67.8%), infections (16.7%) and pigmentary disorders (5.5%). For the speci%c skin diseases, 60.1% were atopic dermatitis (AD), 7.2% were viral warts, 6% seborrhoeic dermatitis and 4.1% vitiligo. Dermatitis was signi%cantly more common in males (p<0.05). AD was the most common condition below 12 years of age, while the presence of viral warts was the most prevalent disorder among HIV-infected children. Approximately one-third (37.5%) of the disorders referred by other medical practitioners were misdiagnosed. Conclusions. AD constituted the highest burden both numerically and economically. Viral infections were a major contribution from HIV infection. !e diverse spectrum and characteristics of skin diseases referred will assist in modifying the dermatology educational curriculum and bridge knowledge gaps among healthcare providers treating childrenItem Prevalence of skin diseases treated at public referral hospitals in KwaZulu-Natal, South Africa(British Association of Dermatologists, 2018) Dlova, N. C.; Chateau, A.; Khoza, N.; Skenjane, A.; Mkhize, Z.; Katibi, O. S.; Grobler, A.; Gwegweni J.T.; Mosam, A.