Browsing by Author "Kolawole, Olatunji Matthew"

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    Dengue virus and malaria concurrent infection among febrile subjects within Ilorin metropolis, Nigeria
    (Wiley-Blackwell, USA, 2017) Kolawole, Olatunji Matthew; Seriki, Adebimpe Adetola; Irekeola, Ahmad Adebayo; Bello, Kizito Eneye; Adeyemi, Oluwapelumi Olufemi
    Dengue is a mosquito-borne disease of public health importance. It is caused by four serotypes of Dengue virus (i.e, DENV-1, -2, -3, and -4). As a result of practices that are conducive for mosquito breading, its vector is widespread in Nigeria and this could result to possible DENV outbreaks in Nigeria and beyond. This study aimed to assess the recency of DENV infection as well as occurrence ofDENVand Malaria co-infections within Ilorin, Nigeria. Blood samples were obtained from 176 febrile subjects and analyzed using Enzyme Linked Immunosorbent Assay (ELISA) for the presence of DENV antibodies. Malaria infection was detected using a rapid diagnostic test kit for malaria parasites. Malaria and DENV (IgM positive) co-infected samples were further subjected to RT-qPCR analysis. A seroprevalence of 46.0% was recorded for anti-DENV IgM antibodies and 2.84% for concurrent Dengue and malaria infections. Out of 95 IgM negative samples, 48 were found to be positive for DENV IgG antibodies. Eleven (6.25%) samples were confirmed DENV positive following RT-qPCR. The CT values of the amplicons were between 19.0 and 20.0. DENV serotype 2 dominated the study, while serotype 3 and 4 were equally distributed. Based on the high seroprevalence of DENV obtained in this study, there is a high possibility of experiencing Dengue virus outbreak in Ilorin, Nigeria, not neglecting the fast geographical spread of the vector. Therefore, surveillance and intensive vector control program should be instituted.
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    Knowledge, Attitude and Practices of Pregnant Women Attending University of Ilorin Teaching Hospital with Regard to Rubella
    (Tehran University of Medical Sciences, 2012) Adeyemi, Oluwapelumi Olufemi; Agbede, Olajide Olubunmi; Kolawole, Olatunji Matthew; Okoh, Anthony
    Objective: This study was carried out to clarify the potential health-risk and to determinant the prevalence of antenatal rubella infection in North-Central, Nigeria. Materials and methods: A descriptive cross-sectional survey was carried out among pregnant women to establish the knowledge, attitude and practices with regards to antenatal rubella infection in eary pregnancy in Ilorin. A total of 92 subjects were recruited by simple random selection from the antenatal clinics of the University of Ilorin Teaching Hospital, Nigeria. Results: Results showed that congenitally defective eyes or ears were regarded as a greater burden to bear than a congenitally defective heart. Pregnant mothers are more likely to abort a congenitally defective fetus before term. Multigravid pregnant women are more likely to have an abortion (X2 =12.48, df = 4, p = 0.014), just as married pregnant women were more likely to abort a congenitally defective fetus before term (X2 = 23.64, df = 4, p = 0.0). Conclusion: It is a general assumption that Nigeria today is majorly rural, therefore, health educational activities for prompt antenatal reporting in sub-urban Ilorin, and Nigeria as a whole, may be a relevant intervention for pregnant women.