Browsing by Author "Kolawole, I.K"

Now showing 1 - 4 of 4
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    An evaluation of effectiveness of preemptive ketamine for postoperative analgesia in elective thyroidectomy
    (Association of General and Private Medical Practitioners of Nigeria, 2021) Oni, O.J; Bolaji, B.O; Kolawole, I.K; Ige, O.A; Oyedepo, O.O; Adegboye, M.B
    Background: The use of preincision low‑dose ketamine as a preemptive analgesic modality has been widely suggested. However, findings from previous studies have remained inconclusive. Materials and Methods: Eighty-two patients scheduled to have elective thyroidectomy under general anesthesia were recruited. The patients were randomly allocated into one of two groups, to receive either 0.5 mg/kg of ketamine intravenously or an equal volume of normal saline, 10 min before surgical incision. At the end of surgery, pain scores, time to first request for analgesic and total opioid requirement in 24 h postoperatively were recorded. Results: There was no significant difference in the postoperative pain scores, time to first requirement for analgesic, postoperative opioid consumption and satisfaction with analgesia between the two groups. The median pain scores at recovery, 2, 6, 12, and 24 h postoperatively for the ketamine and saline groups were not significantly different (P values 0.208, 0.185, 0.412, 0.590, and 0.854 respectively). The times to first request for analgesic were 86.00 ± 56.58 min in the ketamine group and 79.90 ± 68.05 min in the saline group (P = 0.357). The 24‑h opioid (morphine) consumptions were 11.00 ± 3.16 mg in the ketamine group and 13.21 ± 5.87 mg in the control group (P = 0.275). Conclusion: This study concluded that the administration of preincision low-dose ketamine (0.5 mg/kg) did not produce a preemptive analgesic effect in patients who had an elective thyroidectomy.
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    Evaluation of Unanticipated Admission following Paediatric Day-case Surgery in the University of Ilorin Teaching Hospital
    (Published by College of Health Sciences, University of Ilorin., 2021) Adegboye, Majeed B; Kolawole, I.K; Abdulrahman, A.O; Uwadiae, O.I
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    Maternal satisfaction towards spinal anaesthesia for caesarean section
    (Egyptian Society of Anesthesiologist, 2022) Adegboye, M.B; Kolawole, I.K; Adegboye, K.A; Oyewopo, C.I; Oladosu, O.O
    Background: There has been an increase in the use of spinal anaesthesia for Caesarean section (CS) in Nigeria in the past decades. There is, therefore, a need to evaluate the level of satisfaction among patients that had spinal anaesthesia, as an index of the quality of reproductive health care. Methodology: A prospective observational study of 380 consenting parturients in ASA classes I, II, and III, who underwent CS under spinal anaesthesia between January and December 2019. Satisfaction score was assessed using a three-point Likert scale. Data were analysed using [IBM SPSS software version-22]. The level of statistical significance was set at p-value <0.05. Results: A total of 380 consenting patients underwent spinal anaesthesia within the study period with 219 (57.6%) aged ≥30 years. Most were emergency CS 267 (70.3%). Most patients 294 (77.4%) expressed satisfaction for being involved in decision-making about the choice of anaesthesia technique. The majority of the patients 333 (87.6%) were satisfied with pain relief during the operation. The complications experienced by the patients intraoperatively included dizziness, 50 (13.2%), shivering, 139 (36.6%), and intraoperative nausea and vomiting, 48 (12.6%). Overall, 295 (77.6%) of the patients expressed willingness to have spinal anaesthesia again in the future, out of the 295, 293 (99.4%) were satisfied with the current spinal anaesthesia. P = 0.000 Conclusion: Maternal satisfaction to spinal anaesthesia in this study was high. This could be attributed to patient’s participation in decision-making, prompt treatment of complications, and overall good anaesthetic care.
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    Post-operative analgesic and opioid-sparing effect of a single dose pre-operative oral pregabalin in gynaecological surgeries
    (West African College of Surgeons, 2022) Adegboye, K.A; Kolawole, I.K; Bolaji, B.O; Suleiman, Z.A; Adegboye, M.B
    Background: Post-operative pain treatment is a major challenge in our environment. Opioids may cause respiratory depression post-operatively. Therefore, any combination of opioid and non-opioid analgesics that provides quality post-operative pain control and reduces opioid consumption with its attendant side effects will be highly desirable. Objectives: The aim of this article is to evaluate analgesic benefits and opioid-sparing effects of pre-operative oral pregabalin in patients who undergo abdominal gynaecological surgeries. Materials and Methods: A prospective randomized double-blind placebo-controlled study is carried out at University of Ilorin Teaching Hospital, Kwara State, Nigeria. Eighty-two patients scheduled for gynaecological surgeries were randomized into two equal groups. The patients in the control and study groups received a placebo drug and oral pregabalin 150 mg, respectively, 1 h before induction of general anaesthesia. Post-operative pain intensity using a five-point Verbal Rating Scale, time to first request for analgesia, and 24 h post-operative pethidine consumptions were assessed. Mean values were compared using Student’s t-test. Categorical data were compared with the χ2 test. Level of significance was set at 5% (0.05) and power of the study was 80%. Results: Demographic characteristics were comparable between the two groups. The median pain score was 0–2 (no pain–moderate pain) throughout the study. Post-operative static and dynamic pain scores at 1, 4, and 12 h were significantly higher in the placebo group (<0.001). Twenty-four hours post-operatively, there were no significant differences in static and dynamic pain scores between the two groups (P=0.131 and P=0.384, respectively). Time to first analgesic requirement and total pethidine consumed within 24 h post-operative were 47 ± 19 vs. 258 ± 137 min (P=0.001) and 326.19 ± 62.70 vs. 192.86 ± 55.84 mg (P=0.001) in the control and study groups, respectively. The pre-operative use of pregabalin reduced post-operative opioid requirement by 40.9% in the study group. Nausea and vomiting were more common in the placebo group, whereas dizziness, blurring of vision, and sedation were more common in the pregabalin group. Conclusion: A single pre-operative dose of 150 mg oral pregabalin had significantly greater analgesic effects compared with placebo and reduced post-operative opioid requirements in patients undergoing myomectomy or total abdominal hysterectomy. It should be considered an adjuvant in multimodal pain management regimens following gynaecological surgeries