Browsing by Author "Katibi, O.S."

Now showing 1 - 6 of 6
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    Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness
    (American Journal of Tropical Medicine and Hygiene, 2015) Katibi, O.S.; Olaosebikan, R.R; Abdulkadir, Mohammed Baba; Ogunkunle, T.O; Ibraheem, Rasheedat Mobolaji; Murtala, R
    Ackee apple fruit is a native fruit to Jamaica and some parts of west Africa. Its toxicity known as “Jamaican vomiting sickness” dates back to the nineteenth century. However, there is a dearth of reported published data on toxicity from Nigeria where it is popularly known in the southwest as “ishin.” We report a case series of eight previously well Nigerian siblings who presented at various intervals after ingestion of roasted seeds and aril of the ackee fruit.
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    INTELLIGENCE QUOTIENT OF NEUROLOGICALLY IMPAIRED CHILDREN ATTENDING NEUROLOGY CLINIC IN A NIGERIAN TERTIARY INSTITUTION.
    (College of Medicine and Allied Health Sciences, University of Sierra Leone, 2018) Adeboye, M.A.N.; Katibi, O.S.; Adegboye, O. A.; Ojuawo, A.; Afolabi, J.K.; Buhari, O.I.N.; Adegunloye, O. A.; Bello, S.O.; Omefe, P. N.; Abdulazeez, T.A.
    Background: The need to identify the intellectual capability of Neurologically impaired children dictates their educability which can be estimated through their intelligence quotient (IQ). Draw-a-man test for IQ estimation is available, easy and has been validated in Nigeria. Method: Through a prospective, cross-sectional study that lasted 12 months (January-December, 2011), children aged 4 years and above attending neurology clinic were recruited once they have no severe motor or sensory limitations affecting their upper limbs, and can obey instruction to draw a person. Anthropometry was carried out on them and they were comfortably seated to draw a person. The parents or care givers were instructed not to make any suggestion or hint to them and no time limit was given. Their drawings were assessed using the 52 parameters of Ziler and interpreted accordingly. Ethical procedures were adhered to. Analysis was done using SPSS version 16 and an interactive calculation tool for chi-square tests of goodness of fit and independence. Results: Seventy-five (45 male, 30 female) children met the inclusion criteria. Their clinical conditions were Epilepsy 48 (64%), Cerebral Palsy 6 (8%), ADHD 5 (6.7%), Down Syndrome 4 (5.3%), Speech/Hearing impairment 3 (4.0%), Hypothyroidism 2 (2.7%) and 7 (9.3%) others. Their ages ranged from 4 years to 16 years (mean±SD = 9.7± 3.8 years). Their IQ distribution were Normal 4 (5.3%), Borderline 12 (16.0%), Mild Mental Retardation 16 (21.3%), Moderate Mental Retardation 19 (25.3%), Severe and Profound Mental Retardation 24 (32.0%) with no significant difference in relation to their birth order. Conclusions: Ninety-six percent of the study population had IQ below normal. Epilepsy was the commonest condition seen in the Paediatric Neurology clinic and all categories of IQ are seen among children with epilepsy.
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    Mucocutaneous disorders of Paediatric HIV in South-West Nigeria: Surrogates for immunologic and virologic indices
    (South African Medical Association, 2016) Katibi, O.S.; Ogunbiyi, A.O.; Oladokun, R.E.; Ernest, S.K.; Osinusi, K.; Brown, B.J.; Adedoyin, O.T.; Ojuawo, A.I.
    Objectives: Nigeria has the world’s highest burden of pediatric HIV. In the face of paucity of monitoring tests in Nigeria, we studied the spectrum of pediatric mucocutaneous manifestations and evaluated their clinical utility as surrogate markers for immunodeficiency and plasma viral load levels. Methods: Cross-sectional study comparing mucocutaneous manifestations in 155 HIV-positive children aged 12 weeks to 14 years with 155 HIV-negative children. Relationships between mucocutaneous man ifestations in HIV-infected patients and their immunologic and virologic indices were analyzed. Results: Mucocutaneous lesions were seen in 53.5% of HIV-infected children compared with 18.1% of the controls. Prevalence of lesions increased with worsening levels of immunodeficiency and increasing viral loads (P < .01). Oral candidiasis, angular stomatitis, and fluffy hair were associated with more severe degrees of immunodeficiency. Conclusion: Mucocutaneous disorders are common in HIV-infected children. Oral candidiasis and nutritional dermatoses can be used as surrogates for advanced or severe immunodeficiency.
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    Preliminary study on the anti-bacterial activity of 2 cultivars of Acalypha wilkesiana on bacterial isolates of clinical significance
    (Pharmaceutical Society of Nigeria, 2022) Aboh, M.I.; Katibi, O.S.; Salawu, O.A.; Olatunji, K.T.; Fatokun, O.T.; Kola-Mustapha, A.T.; Oladosu, P.O.
    Background: Anti-microbial resistance has become a major problem in clinical practice making it necessary to search for newer molecules. Acalypha wilkesiana, is a herb commonly used traditionally in Nigeria to treat gastrointestinal disorders, wounds and skin infections like impetigo. Objectives: To determine the in-vitro anti-bacterial activity of crude extracts of 2 cultivars of Acalypha wilkesiana (Macrophylla & Hoffmanii) Methods: In-vitro antibacterial activity was investigated by agar diffusion and micro-broth dilution techniques. Bacterial isolates tested were Escherichia coli, Methicillin Resistant Staphylococcus aureus, Staphylococcus aureus, Salmonella paratyphi, Pseudomonas aeruginosa and Klebsiella pneumoniae. Results: The ethanol extract of both cultivars were more active than the ethyl acetate and n-hexane extracts having diameter zones of inhibition against all the bacteria tested at a range of 12.00-22.00 mm. The lowest MIC of the crude ethanol extract was seen with E. coli (1000 µg/ml) and S. aureus(1000 µg/ml; 2000 µg/ml) while the most active fractions (R2, R4, G3 and G4) of the crude ethanol extract of both cultivars had greatest activity against MRSAand P. aeruginosa (156 µg/ml). Conclusion: This study shows that Acalypha wilkesiana has good broad spectrum anti-bacterial activity with the potential for development as lead compounds to combat multi-drug resistant organisms like MRSA.
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    The role of computed tomography in the management of patients with suspected COVID-19; A Nigerian study
    (Journal of Radiation Medicine in the Tropics, 2021) Ajiboye, O.K.; Ayeni, O.; Katibi, O.S.; Umar, U.M.; Osuoji, C.; Agboola, S.A.; Ogedegbe, E.; Ogedegbe, F.
    Background: Computed tomography (CT) of the chest is a useful diagnostic adjunct in the management of COVID-19. It has proven useful in areas where ready access to real-time reverse transcriptase polymerase chain reaction (PCR) is not readily available. Objectives: This study sought to evaluate the chest CT findings of patients suspected with having COVID-19 on presenting at the emergency room. Materials and Methods: This is a retrospective study done in Cedarcrest Hospitals, Abuja, with patient information pooled from patients' electronic medical records from April to December 2020. Patients were selected based on suspicion of COVID-19 infection. Suspicion was stratified into high, moderate, and low using an in-house clinical suspicion score called the Cedarcrest Emergency COVID-19 Risk Assessment Tool. Patients with background pulmonary pathology or chest trauma were excluded. Plain chest CT scans were performed to evaluate for COVID-19 pneumonia. Results: CT imaging increased the clinical suspicion of COVID-19. However, no statistically significant relationship was found between the positive CT findings and the PCR results. Conclusion: Chest CT should be correlated with clinical findings and laboratory results for patient evaluation.
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    Tinea capitis: aetiology, clinical features, and risk factors among school pupils in Ilorin, Kwara state, Nigeria.
    (Nigerian Journal of Dermatology, 2021) Olarinoye, G.; Katibi, O.S.; Ameh, A.; Fayemiwo, S.; Ogunbiyi, A.; George, A
    Background: Tinea capitis (TC) is an identified cause of physical and psychosocial distress among many children in our clime. The predominant aetiological agents have been known to vary with time and geographic location. We sought to determine the current pattern of causative dermatophyte species in our study population. We also aimed to describe the sociodemographic details and prevailing clinical features of TC among the studied children. Methods: The study was a descriptive, cross-sectional study involving 204 children from public primary schools in the Nigerian city of Ilorin, Kwara State. Pupils with clinically diagnosed TC had KOH microscopy and fungal culture done. Results: Trichophyton tonsurans was the most frequently isolated dermatophyte specie. The grey patch was the most common clinical type of TC. Frequently observed variables are male gender, low socioeconomic status, overcrowding, sharing of head garments and hair care instruments, carrying objects on the head and proximity to domestic animals. Over 50% of pupils reported physical or psychosocial distress, while 15.7% had developed permanent hair loss. Despite these, adequate orthodox management was rarely sought. Conclusion: Tinea capitis and its consequences should not be overlooked. A holistic approach at the community level may help reduce the disease burden.