Browsing by Author "Kareem S.B.,"

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    Morphometric study of the jugular foramen and sexual dimorphism using dried skull obtained in two Nigerian States
    (Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria., 2018-12-10) Alabi A.S.,; Ekundayo A.S.,; Oyewopo A.O.,; Kareem S.B.,; Amedu N.O.,; Lewu F.S.,; Akintunde K.A.,; Opayemi R.S.
    Objective: The objective of this study was to determine the morphometric variation between male and female jugular foramen using dried human skulls obtained in two Nigerian states. 'Methods: Atotal of ninety-three (93) dry human skulls were obtained from the osteology collection of the Department of Anatomy, University of Ilorin, Kwara state and Ladoke Akintola University Ogbomosho, Oyo state, Nigeria for this study. Using a digital Vernier caliper various morphometric features were measured. Results: The mean right lateromedial distance was 14.69 (±2.31) mm and 13.78 (±1.95) mm for male and females respectively, the mean left lateromedial distance was 14.40 (±2.34) mm and 14.52 (±2.40) mm. Complete septa in males and females were 31.7% and 9.1% while incomplete septa in males and females 35.0% and 39.4% respectively. Conclusion: There was no significant difference between the jugular foramen of both male and female skulls. The presence of complete septa is more in males while females has more of incomplete septa. The presence of dome, septa and dome height in both sexes were not sexually different from each other
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    Nigella Sativa Attenuates Trimethyltin-induced Histopathological Changes in Mice Hippocampi
    (ASSOCIATION OF SPECIALIST MEDICAL DOCTORS IN ACADEMICS (ASMeDA aka MEDSABAMS), 2022-06) Adana M.Y.,; Imam A.,; Kareem S.B.,; Ajao M.S.
    popular in agriculture and industry. Exposure to the compound is associated with several neurological symptoms which suggest neurotoxicity. The study was designed to investigate the antidotal effects of Nigella sativa (NS) on TMT-induced neurotoxicity on mice hippocamp. Materials and Methods: Seventy adult male mice weighing an average of 25g were randomly assigned into seven groups of ten animals each (Groups A- G). Animals in group A were administered single dose TMT (3mg/kg) and euthanized after 48 hours. Groups B, C, and D were given a single dose of TMT (3mg/kg), followed by a single weekly dose of NS (28ml/kg) for 1, 2, and 3 weeks respectively. Groups E, F, and G served as controls for trimethyltin (3mg/kg), Nigella sativa (28ml/kg), and saline (28ml/kg) respectively. NS. Results: The mice demonstrated tremors, aggressiveness and subtle seizures at the initial state in TMT administered groups with exophthalmos and pedal edema that subsides in the mice administered with TMT-NS. There were exudes of neuritic plaques, neurofibrillary tangles, and apoptotic cells on TMT-administered brains on histology. These observations were markedly reduced in the TMT-NS administered groups. Conclusion: The study concludes that the neurodestructive effects of TMT on the hippocampal neurons and its ability to negatively affect the neuro behavioral attitudes of the mice could be reversible following the administration of NS