Browsing by Author "Irole-Eze,O.P"

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    Distribution and seasonal abundance of Anopheline mosquitoes and their association with rainfall around irrigation and non irrigation areas in Nigeria
    (UNED: Research journal in Costa Rica, 2018-12) Amaechi,E.C; Ukpai,O.M; Ohaeri,C.C; Ejike, B.U; Irole-Eze,O.P; Egwu, O; Nwadike, C.C
    The abundance of Anopheline mosquito species is the most common entomological measurement to determine the relationship between vectors and malaria incidence. We conducted an entomolog ical survey to determine mosquito species diversity and abundance in relation to rainfall in Omi reservoir irrigation area, Nigeria. We col lected adult mosquitoes from 10 randomly selected residential houses using Pyrethrum spray sheet and Human Landing Catch methods. We grouped the samples into irrigated (intervention) and non-irrigated (control) communities. During the 12-month sampling period, we col lected a total of 4 285 mosquitoes belonging to 10 species in one fam ily. The three most common species during this study were Anopheles gambiae, Anopheles funestus and Culex quinquefasciatus. Irrigated community has higher numbers of mosquitoes (69,4%) compared to those collected in non-irrigated community (32,0%). Comparing the two collection methods used, Pyrethrum spray sheet has a greater number 2 225(75,4%) of mosquitoes than those with Human Landing Catch method 724(24,6%). During dry season, we collected fewer mos quitoes. The lowest number was collected in February (114) and the highest occurring during the wet season in July (445).
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    Evaluation of microscopy and rapid diagnostic tests for diagnosing malaria among febrile subjects in Ezinihitte Local Government Area, Imo State, nigeria
    (Institute of Biology, 2019) Irole-Eze,O.P; Ukpai,O.M; Ejike,B.U; Nwadike,C.C; Egwu,O; Okorocha, N.A; Amaechi,E.C
    Malaria is the leading cause of morbidity and mortality in Nigeria, the country accounting for the highest devastation worldwide. This study aimed at evaluating the performance of microscopy and rapid diagnostic tests (RDTs) for diagnosis of malaria. A total of 443 suspected Plasmodium falciparum infected patients in hospitals in selected communities of Ezinihitte Local Government Area south eastern Nigeria between January and June 2014 were examined by using microscopy and RDTs. Thick and thin blood smears made on clean slides from venipuncture blood collected from febrile subjects have been examined for the presence of malarial parasites. Serological diagnosis was performed using Carestart, SD Bioline and Antec kits. The overall prevalence of the three RDTs were Carestart pf (41.8%), SD Bioline pf (52.8%), and Antec pf/pv (25.3%) as against microscopy the standard (44.9%). The varied prevalence observed from the three kits did not differ statistically (p>0.05).The females appeared to have more infected (42.4%) than the males (39.6%) with no significant difference between the diagnostic methods. The overall sensitivities of Carestart pf, SD Bioline pf and Antec pf/pv were 71.9%, 86.9% and 50.8% respectively while their corresponding specificities were 82.8%, 75.0%, and 95.5% respectively. SD Bioline HRP2 based test demonstrated a superior sensitivity compared to microscopy. Some RDTS can be useful alternatives to microscopy in the diagnosis of P. falciparum especially in resource limited communities.
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    Prevalence of falciparum malaria amongst pregnant women in Aba south Local Government Area, Abia State, Nigeria
    (Parasitology and Public health Society of Nigeria, 2017-03) Ejike,B.U; Ohaeri,C.C; Amaechi,E.C; Ejike,E.N; Okike-Osisiogu, F.U; Irole-Eze,O.P; Belonwu,A.C
    Malaria during pregnancy poses a substantial risk to mother and foetus especially an infection with Plasmodium falciparum. This study was undertaken to assess the prevalence of falciparum malaria among pregnant women in Aba South Local Government Area, Abia State, south-east Nigeria. Blood samples from 432 pregnant women who attended Primary Health Care Centre and Abia State University Teaching Hospital (ABSUTH) were examined using Giemsa stained thick and thin films. Structured questionnaires were also administered to the women from whom blood samples were collected. A total of 173 (40.0%) were found to be infected with P. falciparum. It was the only type of malaria parasite species encountered. Distribution of infection among age groups was highest 12 (60.0%) among age group 15-20 years and lowest 121 (36.7%) among age group 26 years and above with significant difference (p<0.05). Occupational distribution showed that traders had the highest prevalence 88 (63.3%) while students were least infected 21 (17.9%) with significant difference (p<0.05). Primigravida had the highest prevalence rate of 99 (50.3%) while multigravida had the lowest rate 38 (27.1%) with significant difference (p<0.05). Respondents who were at their first trimester also showed a high prevalence rate 69 (56.6%) while those in their third trimester were least infected 28 (30.1%) with significant difference (p<0.05). It is therefore necessary to design an effective public health education programme targeted at this high risk group and also instituting an intermittent preventive treatment in hospitals and health centres in Aba South LGA that is known to have a high malaria prevalence.