Browsing by Author "Hambali, M. A."

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    Feature selection and computational optimization in high-dimensional microarray cancer datasets via InfoGain-modified bat algorithm
    (Multimedia Tools and Applications, 2022) Hambali, M. A.; Oladele, Tinuke Omolewa; Adewole, K. S.; Sangaiah, A. K.; Gao, W.
    Achieving a satisfactory cancer classification accuracy with the complete set of genes remains a great challenge, due to the high dimensions, small sample size, and presence of noise in gene expression data. Feature reduction is critical and sensitive in the classification task, most importantly in heterogeneous multimedia data. One of the major drawbacks in cancer study is recognizing informative genes from thousands of available genes in microarray data. Traditional feature selection algorithms have failed to scale on large space data like microarray data. Therefore, an effective feature selection algorithm is required to explore the most significant subset of genes by removing non-predictive genes from the dataset without compromising the accuracy of the classification algorithm. The study proposed an information Gain – Modified Bat Algorithm (InfoGain-MBA) features selection model for selecting relevant and informative features from high dimensional Microarray cancer datasets and evaluate the approach with four classifiers - C4.5, Decision Tree, Random Forest and classification and regression tree (CART). The results obtained show that the proposed approach is promising for the classification of microarray cancer data. The random forest has 100% accuracy with few genes in all seven datasets used. Further investigations were also conducted to determine the optimal threshold for each of the datasets.
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    Microarray cancer feature selection: Review, challenges and research directions
    (International Journal of Cognitive Computing in Engineering (IJCCE), Elsevier B. V., 2020) Hambali, M. A.; Oladele, Tinuke Omolewa; Adewole, K. S.
    Microarray technology has become an emerging trend in the domain of genetic research in which many researchers employ to study and investigate the levels of genes’ expression in a given organism. Microarray experiments have lots of application areas in the health sector such as diseases prediction and diagnosis, cancer study and soon. The enormous quantity of raw gene expression data usually results in analytical and computational complexities which include feature selection and classification of the datasets into the correct class or group. To achieve satisfactory cancer classification accuracy with the complete set of genes remains a great challenge, due to the high dimensions, small sample size, and presence of noise in gene expression data. Feature reduction is critical and sensitive in the classification task. Therefore, this paper presents a comprehensive survey of studies on microarray cancer classification with a focus on feature selection methods. In this paper, the taxonomy of the various feature selection methods used for microarray cancer classification and open research issues have been extensively discussed.