Browsing by Author "Fawole, Adegboyega Adisa"
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Item PREVALENCE OF HEPATITIS B VIRUS INFECTION AMONGST PATURIENTS IN THE UNIVERSITY OF ILORIN TEACHING HOSPITAL(The Society of Gastroenterology and Hepatology in Nigeria (SOGHIN), 2015-06) Ogunlaja, Olumuyiwa Ayotunde; Bojuwoye, Matthew Olumuyiwa; Fawole, Adegboyega Adisa; Adesina, A.K.; Olawumi, H.O.; Ogulaja, Idowu PaulineBackground: Hepatitis B virus (HBV) infection is endemic in Nigeria and indeed the whole of Sub-Saharan Africa. The Society of Gastroenterology and Hepatology in Nigeria (SOGHIN) recommends HBV screening for all Nigerians to pave way for early detection and treatment of the infection in those who are infected and prevention of infection in individuals who are free of the infection via immunization. Identifying seropositive paturients and taking steps to deter vertical transmission are important preventive strategies. This study, therefore, sought to determine the seroprevalence rate of HBV infection among paturients seen at a tertiary hospital in Ilorin. Patients and Methods: This was a prospective observational study of pregnant women seen between September 1 to December 31, 2012 at the Ante-natal clinic of the Department of Obstetrics and Gynaecology, University of Ilorin Teaching Hospital (UITH), Ilorin. Demographic information, relevant medical information and blood samples for screening were taken from all booked and unbooked pregnant women after obtaining informed consent. The serologic test done was a qualitative one using immunochromatographic test strips to screen for the presence of Hepatitis B surface antigen (HBsAg) in the sera of the study subjects. Results: A total number of 237 pregnant women were enrolled into this study during the study period (mean age 31.2 ± 3.4 years). Thirty (12.7%) of the study subjects had positive test results to the presence of HBsAg in their sera. Hence, the HBV seroprevalence rate in this study was 12.7%. Conclusion and recommendations: This study has shown a high HBV seroprevalence rate of 12.7% among pregnant women seen at UITH. It is our recommendation, therefore, that HBV screening be included among the routine antenatal investigations for all pregnant women in UITH and the community at large.Item Prevalence Of Human Immunodeficiency Virus & Hepatitis B Virus Co-Infection In A Population Of Apparently Healthy Pregnant Women In University Of Ilorin Teaching Hospital, Ilorin(College of Health Sciences, University of Ilorin, Ilorin, 2016-01) Ogunlaja, Olumuyiwa Ayotunde; Fawole, Adegboyega Adisa; Bojuwoye, Matthew Olumuyiwa; Idowu, Ajibola; Ogunlaja, Idowu PaulineItem Ultrasound estimation of amniotic fluid and perinatal outcome in normotensive and pre-eclamptics at term in a Nigerian tertiary hospital(School of Medicine and Health Sciences, University for Development Studies, Tamale, Ghana, 2015) Ogunlaja, Olumuyiwa Ayotunde; Fawole, Adegboyega Adisa; Adeniran, A. S; Adesina, Kikelomo T; Akande, H. J.; Ogunlaja, Idowu Pauline; Bojuwoye, Matthew Olumuyiwa; Idowu, AjibolaPre-eclampsia is a subtype of hypertensive disorder in pregnancy which is described as a disorder of widespread vascular endothelial malfunction and vasospasm that manifest clinically after 20 weeks gestation and can present as late as 4-6 weeks postpartum. However, the focus in modern obstetric care is on reduction of maternal and perinatal morbidity and mortality through preventive strategies. The objective of this study was to determine the usefulness of ultrasound scan measurement of the amniotic fluid indices in determining perinatal outcome in normotensive and preeclamptic paturients at term. This was an observational study involving 120 consenting preeclamptics and 120 normotensive women. An analysis of the measures of perinatal outcome in this study revealed a statistical significant difference when meconium stained liquor, route of delivery, fetal outcome and birth weight in pre-eclamptic women were compared with those of normotensive women. Ultrasound estimation of amniotic fluid in pre-eclamptic and normotensive paturients has been found to be useful in the management of these patients with the aim of improving perinatal outcome. Hence, there may be a need to include this in the protocol of management; however, randomized control trials will be needed to further justify the finding of this recommendation.