Browsing by Author "Fadeyi, A."
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Item Impact of Malaria Parasitaemia on Haematologic Parameters in Pregnant Women at Booking in Ilorin, Nigeria(Science Alert, 2009) Adesina, K.T.; Balogun, O.R.; Babatunde, A. S.; Sanni, M.A.; Fadeyi, A.; Aderibigbe, S.We determined the pattern of haematological parameters in malaria in pregnancy. Five hundred pregnant women who presented for booking in the antenatal clinic of the University of Ilorin Teaching Hospital, Ilorin, Nigeria were recruited. Their blood samples were analyzed for malaria parasites, MCV, MCHC and MCHC, WBC, absolute RBC count, platelet count, haemoglobin level and PCV. The prevalence of peripheral malaria parasitaemia at booking was 32.4%, out of which 46.9 and 53.1% had moderate and high parasite densities, respectively. Plasmodium falciparum was the only species identified. The MCHC was higher in malaria parasitaemia (34.28 g dL-1±1.72, p = 0.0452) while RBC was higher without parasitaemia (10.46x1012 L-1±1.30, p = 0.01). The WBC in women with high parasite density (7.02x109 L-1) was higher than the value in those with moderate parasite density (6.26x109 L-1) p = 0.03). Asymptomatic Plasmodium falciparum infection in pregnancy is associated with higher MCHC; WBC increases with rise in the parasite density in Ilorin, Nigeria. A rise in MCHC and WBC in pregnancy may indicate malaria.Item Malaria Parasitaemia and Anaemia among First Antenatal Clinic Attendees in Ilorin, Nigeria(Pan Africa Medical Journal, 2010) Fadeyi, A.; Balogun, O.R.; Babatunde, A.S.; Adesina, K.T.; Aderibigbe, S.; Sani, M.A.The burden of malaria and anaemia in pregnancy is unknown in Ilorin, Nigeria despite malaria being threat to 2.4 billion lives world-wide including Nigerians particularly the children and pregnant women. To determine the prevalence of malaria parasitaemia and anaemia in pregnancy among first antenatal clinic attendees at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria, 500 consecutive, consenting pregnant women presenting for antenatal care at UITH, Ilorin for the first time were screened for malaria parasitaemia and anaemia over a 1 year period starting from June 2008. Information about participants’ socio-demographic data, fever, anti-malaria therapy including prophylaxis using intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp/SP) among others were also obtained at recruitment. The prevalence of malaria parasitaemia and anaemia in the women were 32.4% and 25.8 respectively. The women’s age, parity and educational level did not affect either malaria parasitaemia (MP) or mean parasite density (MPD) but gestational age (GA) significantly (F = 6.02, p = 0.002) affected MPD as women in the first trimester (35.7%) were most infected. The mean haemoglobin concentration (MCH) was significantly associated with maternal age (f = 3.33, p = 0.005) and parity ((f – 23.97, p = 0.000), and varied inversely as the MPD. Maternal fever was not a good predictor of MP as only 7 (46.7%) of 162 (32.4%) malaria parasitaemic women were febrile. There was no significant difference (f = 1.4, p = 0.23) in the mean malaria parasite densities of anaemic compared with non-anaemic women but there was significant difference in the prevalence of MP (X2 = 1.135, p = 0.0007549) and anaemia (X2 = 8.634, p = 0.0000) among users and non-users of IPTp/SP. Malaria parasitaemia and anaemia remains a threat in pregnancy in Ilorin, Nigeria with the affected often afebrile. Since users of IPTp/SP in pregnancy were better protected against malaria parasitaemia and anaemia in pregnancy, early antenatal booking and use of IPTp/SP is desired.Item Methicillin Resistant staphylococcus aureus (MRSA): Awareness, Knowledge and Disposition to Screening Among Healthcare Workers in Critical Care Units of A Nigerian Hospital.(West African Medical College of Physician, 2011) Fadeyi, A.; Adeboye, M. A. N.; Fowotade, A.; Nwabuisi, C.; Bolaji, B. O.; Oyedepo, O. O.; Adesiyun O. O.; Olanrewaju, T. O.; Aderibigbe, A.; Salami, A. K.; Desalu, O. O.; Akanbi II, A. A.; Raheem, R. A.; Olalere, A.BACKGROUND: Awareness level about methicillin resistant Staphylococcus aureus (MRSA) is high in the western world but the status in developing countries is not well defined. OBJECTIVE: To assess MRSA awareness level, knowledge and disposition to screening among critical healthcare givers (HCGs) in Nigeria. METHODS: A self-administered questionnaire was used to assess the level of awareness and knowledge of HCGs in critical care units of the University of Ilorin Teaching Hospital, Ilorin, Nigeria on MRSA and their willingness to submit to screening. RESULTS: Only 103 (52.0%) of the 198 participants were aware of MRSA but all were favourably disposed to screening for the organism. Awareness was through hospital rounds 65(63.1%) and journals/ textbooks 35(34.0%), and Many, 120 (60.6%) considered MRSA as a threat in the hospital, while only 27 (13.6%) thought otherwise and 51(25.8%) were indifferent. Most HCGs, 124 (87.9%) reported that there were no MRSA control measures in their respective duty post. The age, cadre of work, and number of years in the hospital’s critical care units correlated positively with awareness level. CONCLUSION: Methicillin resistant Staphylococcus aureus awareness level among the HCGs in our hospital is just a little above 50.0% with substantial proportion of them not realizing the medical implication of the organism. However, majority are well disposed to MRSA screening. Inadequate publicity is a major contributor to poor knowledge and awareness. There is need for educational intervention and sensitization programs on MRSA and other infection control techniques for HCGs in developing nations especially Nigeria.Item Mortality pattern within the first twenty four hours of emergency Paediatric admission in resource poor nation health facility.(West African Medical College of Physician., 2010) Adeboye, M. A. N.; Ojuawo, A.; Ernest, S. K.; Fadeyi, A.; Salisu, O. T.BACKGROUND: Mortality among emergency paediatric admissions within the first 24 hours is high in resource- poor nations. Measures to reduce the childhood mortality rate can only be effectively planned and implemented when the causes and magnitude of this problem are well defined. OBJECTIVE: To determine the mortality pattern among emergency paediatric admissions within the first 24 hours in a health facility in Nigeria. METHODS: The clinical state and progress of post-neonatal patients who presented alive and were admitted into the emergency paediatric room of the University of Ilorin Teaching Hospital, Ilorin, Nigeria were monitored over a period of six months. The monitoring included records of diagnosis and outcome of management. RESULTS: A total of 606 children were admitted during the period of study out of which 51(8.4%) died. Twenty-nine (57%) of the deaths occurred within the first 24 hours of admission comprising 15 (51.7%) males and 14 (48.3%) females giving M:F ratio of about of 1:1. Majority of the deaths were among patients who reported late to the hospital. Loss of consciousness was a strong risk factor for mortality within 24 hours of admission. The highest mortality within the first 24 hours of admission was recorded among patients with malaria (89.0%) followed by protein energy malnutrition. CONCLUSION: Majority of deaths among emergency paediatric admission occur within the first 24 hours of admission and are associated with clinical conditions such as malaria and protein-energy malnutrition for which sustained intervention strategies must be developed.Item SERO-PREVALENCE OF HEPATITIS B AND C AMONG MENTALLY ILL PATIENTS ATTENDING A TERTIARY HOSPITAL IN NIGERIA(Annals of African Medicine Society and Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria, and is affiliated to the Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria,, 2014) Durotoye, I A.; Issa, B.A; Fadeyi, A.; Yussuf, A.D; Salami, A.K; Shittu, O.A; Ajiboye, P.O; Olawumi, H.O.; Adegunloye, O.A; Nwabuisi, Charles; Sulyman, D.Background: Hepatitis B and C are of global concern and Nigeria is a high endemic zone for the viruses. Persons with severe mental illness have a greater vulnerability to sexual transmitted infections including hepatitis B&C due to risky behaviour they engage in. The aim of this study is to determine the sero- prevalence of hepatitis B and C among persons with mental illness (MII) and compare them with blood donors (BDs) at University of Ilorin Teaching Hospital (UITH), Nigeria. Methods: A prospective cross-sectional study conducted over a period of 1year, starting from June, 2010, involving 350 each of BDs and MII in an out-patients department of UITH. HBsAg testing was by a one stage hepatitis B surface antigen test strips, while hepatitis C was tested using commercially prepared kits from ACON, USA. Result: A total of seven hundred participants including 350 patients with MII and 350 blood donors (BDs) were recruited for the study. Most 324(92.6%) and 349 (99.7%) were of the age range ≤55 years. There were 179(51.2%) males and 171(48.8%) females. More married BDs live with their spouses (99.0%) and had higher education than MII. Unemployment rate was higher among MII than BDs. The sero-prevalence of Hepatitis B and C among patients with mental illness (MII) was 10.0% and 12.6% respectively as compared to a sero-prevalence of 10.9% and 1.1% in the blood donors. Conclusion: The prevalence of hepatitis B infection was similar in both subjects (MII) as well as in the blood donors but, in contrast however was higher prevalence of hepatitis C in the MII (p=0.001). Routine screening of MII for hepatitis B and C is advocated to control the complications that may arise from these diseasesItem Sero-Prevalence of Syphilis among Patients with Mental Illness: Comparison with Blood Donors(Osun State University, 2014) Issa, B.A; Fadeyi, A.; Durotoye, I A.; Yussuf, A.D; Salami, A.K; Shittu, O.A; Ajiboye, P.O; Olawumi, H.O.; Adegunloye, O.A; Mwabuisi, C.; Sulyman, D.BACKGROUND: Mentally ill individuals (MII) are at risk of acquiring syphilis and other sexually transmitted infections. This study aimed at determining sero-prevalence of syphilis among MII and compare them with voluntary blood donors (VBD) at University of Ilorin Teaching Hospital (UITH), Nigeria. METHODS: A cross-sectional study done between June, 2010 and June 2011, and involving 350 each of VBDs and MII in and out-patients of UITH. Serological test was done using venereal disease research laboratory (VDRL) and the Treponema Pallidum Haemagglutination (TPHA) kit. RESULTS: Of the 700 subjects, 324 (92.6%) MII, and 349 (99.7%) VBDswere <55 years; 71 (21.4%) MII were Civil Servants compared with 96 (27.4%) VBDs. Significantly more VBDs had higher education than MII (185 or 52.9%, and 140 or 40% respectively). Christians constituted the majority (176 or 50.3%) among MII, and Muslims (210 or 60%) among VBDs. Significantly more married VBDs (204/206 or 99.0%) live with spouses; more VBDs consumed alcohol (37 or 10.6%), smoked (19 or 5.4%), and engaged in extramarital sex (105 or 30.0%). Significantly more MII had blood transfusion (40 or 11.4); engaged in sex trade (12 or 3.4%); and more syphilis prevalence (5.4%). In addition, more syphilitic MII smoked(18 or 94.7%); and all syphilitic MII had psychotic disorders. CONCLUSION: The prevalence of syphilis in MII is significantly higher than among VBDs. Routine screening of MII is advocated to stem this problem.WAJM 2013; 32(2):210–215.Item Urinary bacterial isolates and their antibiotic sensitivity patterns at University of Ilorin Teaching Hospital, Ilorin, Nigeria(University of Ilorin, 2006) Akanbi II, A.A.; Fadeyi, A.; Atata, R.F.; Babatunde, A.S.; Samuel, S.O.