Browsing by Author "Durowade, K.A"

Now showing 1 - 7 of 7
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    Clomiphene resistant polycystic ovarian syndrome: Analysis of outcomes following laparoscopic ovarian drilling in infertile women in Ilorin, North-central, Nigeria
    (African Health Research Organization, 2017) Omokanye, L.O; Olatinwo, A.O; Pati, A; Ibrahim, S; Durowade, K.A; Oyedepo, O.O; Ige, O; Adegboye, M.B.
    Background: Laparoscopic ovarian drilling (LOD) is one-off treatment modality for clomiphene citrate (CC)-resistant polycystic ovarian syndrome (PCOS) avoiding the need of medical therapy and its attendant complications. Aims and Objectives: This study aimed at determining the efficacy of LOD in women with anovulatory infertility secondary to CC‑resistant PCOS and factors influencing reproductive outcomes. Materials and Methods: A cross-sectional study of infertile women who underwent LOD on account of CC-resistant PCOS between January 2012 and December 2015 at a tertiary institution. Results: Patients aged 24–38 years (29.7 ± 3.6 years) and their body mass index (BMI) ranges from 20 to 35 (26.3 ± 4.3). The majority (90.5%) were nulliparous. Most (61.3%) had primary infertility. Their duration of infertility ranges from 1 to 13 years (4.3 ± 2.7) and ovarian volume ranges from 10 to 24 cm3 (mean, right ovary = 15.2 ± 3.2; left ovary = 16.3 ± 3.2). The number of drills per ovary ranged from 4 to 14 (mean, right ovary = 7.4 ± 2.1; left ovary = 7.3 ± 2.1) and the luteinizing hormone/follicle stimulating hormone (LH)/FSH ratio ranges from 2 to 6 (3.2 ± 1.4). All achieved spontaneous resumption of menses and ovulation with mean durations of 4.0 ± 1.8 days and 5.3 ± 3.2 weeks, respectively. Eighty-three (60.6%) clinical pregnancies were recorded, of which 68 (49.6%) resulted to live births (61 singletons and 7 twin births) and 14 (10.2%) early first trimester miscarriages. The mean time interval from LOD to pregnancy was 4.4 ± 1.1 months. There was a significant association between BMI, duration of infertility, FSH/LH ratio, and pregnancy outcomes (P < 0.05). Conclusion: LOD is the most preferred treatment modality for CC-resistant PCOS as it resulted in higher pregnancy rate.
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    Determinants of infertility in male partners of infertile couples at a public health facility in Ilorin, Nigeria
    (Regional Institute of Medical Sciences, Imphal, India, 2016) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K.A; Abdul, I.F; Biliaminu, S.A
    Background: Infertility is the most important reproductive health and social issue confronting married couples in our environment. The contribution of male factor is assuming a tremendous proportion. Seminal fluid analysis (SFA) remains an indispensable tool in the evaluation of the fertility potential of these male partners. Aim and Objectives: This study aimed to determine the pattern of seminal fluid parameters and its impact on infertility among male partners of infertile couple at a public health facility in Ilorin. Materials and Methods: A cross‑sectional study of the seminal fluid indices of consecutively consenting male partners of infertile couple seen at the Assisted Reproductive Technology (ART) Unit of the Department of Obstetrics Gynecology, University of Ilorin Teaching Hospital, Ilorin, between January 1, 2012 and December 31, 2014. Results: All male partners of infertile couple who had infertility consultation at the ART unit consented to SFA during the study period. The patients were aged 27–67 years. One hundred and seventy‑five (56.1%) patients had normal parameters. There was a high level of leukocytospermia and bacterial infections in both normospermic and oligospermic semen. The predominant organism was Staphylococcus aureus. Of the sociodemographic and reproductive/hormonal variables, only the age was found to have statistically significant association with types of infertility. Conclusion: Male factor is increasingly assuming a significant role in the etiology of infertility in Ilorin. The practitioners should, therefore, endeavor to involve them early in the overall management to reduce stigmatization and ostracizing of women for infertility.
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    Determinants of voluntary blood donation among adults in communities of north central region of Nigeria
    (Osun State University, 2019-06-30) Salaudeen, AG; Durowade, K.A; Durotoye, I A.; Ahmed, A.; Sanni, E.O; M, O.I; Akande, T.M
    Objective: The collection of blood from voluntary, non-remunerated blood donors is an important measure for ensuring the safety, quality, availability and accessibility of blood. The study assessed factors affecting voluntary blood donation in North-central zone, Nigeria. Methods: The study design was descriptive cross-sectional, data was collected using a pre-tested interviewer administered questionnaire from 3104 respondents using multistage sampling technique. Data was analyzed using EPI INFO computer software package (version 3.5.3). Level of significance was pre-determined at p-value < 0.05 at a confidence level of 95%. Results: Respondents with good knowledge of voluntary blood donation had better practice of voluntary blood donation. Younger age groups were 8 times more likely to donate blood voluntarily than older respondents. Yoruba ethnic groups are 1.5 times more likely to donate blood than other ethnic groups. Conclusion: For Nigeria and other developing countries at large to achieve 100% voluntary blood donation drive by year 2020, it is critical to change the blood donation culture from replacement to that of volunteerism through more effective communication and mobilization of donors. These efforts must be rendered more methodical and accomplished through a wider range of strategies.
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    Pregnancy outcomes following Assisted Reproduction Technology for infertile women at a public health institution in Nigeria
    (College of Health Sciences, University of Ilorin, 2015) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K.A; Biliaminu, S.A.; Salaudeen, A.G.; Panti, A.A.
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    Prevalence of antibody to hepatitis B core antigen among hepatitis B surface antigen-negative blood donors in Ilorin, Nigeria
    (Malawi Medical Association, Malawi, 2017-03) Ogunfemi, M.K; Olawumi, H.O.; Olokoba, A.B; Kagu, M.B; Biliaminu, K.A; Durowade, K.A; Durotoye, I A.; Shittu, A.O.
    Background Post-transfusion hepatitis occurs even with stringent donor selection criteria and screening for hepatitis B surface antigen (HBsAg). The objective of this study was to determine the prevalence of antibody to hepatitis B core antigen (anti-HBc) in HBsAg-negative blood donors. Methods This was a cross-sectional study in which 200 HBsAg-negative blood donors were recruited. Screening for viral markers was done using both a rapid test kit and enzyme-linked immunosorbent assay (ELISA) for anti-HBc IgM. Quantitative and qualitative analysis of anti-HBc IgM was done by “capture” enzyme immunoassay using DIA.PRO HBc IgM test kit. The other viral markers were investigated using one step cassette style HBV tests. SPSS (version 16) was used for data analysis. A P-value of 0.05 or less was considered significant. Results There were 190 male (95%) and 10 female (5%) blood donors, with a mean age of 31.7 ± 7.9 years. The prevalence of anti-HBc IgM was 4%. The other viral markers (HBeAg, anti-HBeAg, anti-HBs and total anti-HBc) had a prevalence of 1.5%, 23%, 2.5%, and 32.5%, respectively. Conclusions The prevalence of anti-HBc IgM in this study wsa high, and this supports the fact that screening blood donors for HBsAg alone is not sufficient to prevent transmission of HBV.
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    PREVALENCE, RISK FACTORS OF HUMAN PAPILLOMAVIRUS INFECTION AND PAPANICOLAOU SMEAR PATTERN AMONG WOMEN ATTENDING A TERTIARY HEALTH FACILITY IN SOUTH-WEST NIGERIA
    (Turkey Periodical of Gulhane Medical Faculty, Gulhane Medical Academy, 06019, Ankara, 2015) Kolawole, O.M; Olatunji, K.T; Durowade, K.A; Adeniyi, A.A; Omokanye, L.O
    Background: Cervical cancer amongst Nigerian women has been on the increase in the past decade, and is regarded as the second highest cause of cancer deaths among Nigerian women. Objective: This study was aimed at determining the prevalence, risk factors of HPV infection, and Papanicolaou smear pattern amongst a cohort of women attending the Gynaecology clinic of a tertiary health facility in Ido-Ekiti, South west Nigeria. Methodology: This was a cross-sectional study involving the screening of women between the ages of 15-64 years for cervical intraepithelial neoplasia using Papanicolaou smear staining technique and serological diagnosis using IgG enzyme linked immunosorbent assay kits. Respondents were selected through convenience sampling of subjects, while intervieweradministered questionnaire and clinical report form were also used to collect data, and data was analyzed using SPSS version 17. Result: Of the 200 blood samples examined for Human papillomavirus infection, 135 (67.5%) were sero-positive while 65 (32.5%) were sero-negative. For cervical cytology using Papanicolaou smear, 14 (7%) were positive (had presence of cervical abnormality) while 186 (93%) were negative (had no cervical abnormality). Result showed a direct relationship between seropositivity, development of cervical intraepithelial neoplasia and Human papillomavirus infection. The risk factors for the development of HPV infection included age, type of marriage, parity, history of genital infection and tobacco usage. Non circumcision of male partner was also found to be a risk factor. Conclusion: The presence of abnormal cervical cytology and high level of serological positivity clearly showed why there is need for a holistic approach to the screening, vaccination methodologies and early detection of HPV infection in the country.
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    Traditional eye pencil: A rural- urban comparison of pattern of uptake and association with glaucoma among adults in selected communities of North Central Nigeria
    (African Health Research Organization, 2017) Durowade, K.A; Salaudeen, A.G.; Musa, O.I; Olokoba, L.B; Omokanye, L.O; Akande, T.M