Browsing by Author "Bisalla, M."

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    Ameliorative Effect of Methanol Extract of Tiger Nut (cyperus Esculentus) On Oxidative Stress Induced By Lead Poisoning In Red Sokoto Goat
    (Faculty of Veterinary Medicine, University of Abuja, 2019-12) Adam, M.; Esievo, K. A. N.; Ayo, J. O.; Bisalla, M.; Adamu, S.
    Tiger nut is a small tuberous rhizome with medicinal and antioxidant properties. The present study was conducted to investigate the ameliorative effect of the methanol extract of tiger nut against the oxidative stress induced by lead acetate poisoning in Red Sokoto goat (RSG). Twelve adults Red Sokoto goat (16.50 ± 1.41 to 21.92 ± 0.97 kg) were grouped into four. Group I was administered with equivalent volume of distilled water. Group II was administered with lead acetate (200 mg/kg) only. Group III was administered with methanol extract of tiger nut (METN) (150 mg/kg) and lead acetate (200 mg/kg). Group IV was administered METN (200 mg/kg) only. The serum oxidative stress changes in the different experimental groups were determined by commercial kits. The distilled water group showed no toxic response. The lead acetate (200 mg/kg) group showed decreased activity levels of glutathione, superoxide dismutase (SOD) and catalase (CAT). The cotreatment groups with lead acetate and METN showed an increase in serum glutathione peroxidase (GPx) activity, CAT and SOD. Additionally, there was a decreased MDA concentration in the same group. The group administered with METN only showed slight changes in the activities of oxidative stress makers. In conclusion, Oxidative stress biomarkers such as glutathione peroxidases, superoxide dismutase, catalase and malondialdehyde were altered in a manner indicative of oxidative stress following lead acetate exposure and ameliorated to some extent by methanolic extract of tiger nut.
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    Ameliorative Effect of Methanol Extract of Tiger Nut (cyperus Esculentus) On Oxidative Stress Induced By Lead Poisoning In Red Sokoto Goat
    (Faculty of Veterinary Medicine, University of Abuja, 2019-12) Adam, M.; Esievo, K. A. N.; Ayo, J. O.; Bisalla, M.; Adamu, S.
    Tiger nut is a small tuberous rhizome with medicinal and antioxidant properties. The present study was conducted to investigate the ameliorative effect of the methanol extract of tiger nut against the oxidative stress induced by lead acetate poisoning in Red Sokoto goat (RSG). Twelve adults Red Sokoto goat (16.50 ± 1.41 to 21.92 ± 0.97 kg) were grouped into four. Group I was administered with equivalent volume of distilled water. Group II was administered with lead acetate (200 mg/kg) only. Group III was administered with methanol extract of tiger nut (METN) (150 mg/kg) and lead acetate (200 mg/kg). Group IV was administered METN (200 mg/kg) only. The serum oxidative stress changes in the different experimental groups were determined by commercial kits. The distilled water group showed no toxic response. The lead acetate (200 mg/kg) group showed decreased activity levels of glutathione, superoxide dismutase (SOD) and catalase (CAT). The cotreatment groups with lead acetate and METN showed an increase in serum glutathione peroxidase (GPx) activity, CAT and SOD. Additionally, there was a decreased MDA concentration in the same group. The group administered with METN only showed slight changes in the activities of oxidative stress makers. In conclusion, Oxidative stress biomarkers such as glutathione peroxidases, superoxide dismutase, catalase and malondialdehyde were altered in a manner indicative of oxidative stress following lead acetate exposure and ameliorated to some extent by methanolic extract of tiger nut.
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    Reproductive pathology of experimentally induced lead poisoning in Red Sokoto Buck: Protective effect of tiger nut (Cyperus esculentus).
    (Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt., 2020) Adam, M; Esievo, K.A.N.; Bisalla, M.; Ayo, J.O.; Aliyu, A.I.; Akanbi, O.B.; Baba, A.Y.; Raji L.O.; Salleh, A.
    Tiger-nut (Cyperus esculentus) is a crop that belongs to family Cyperaceae which produces rhizome and tuber that are small spherical in shape. The tubers have aphrodisiac, carminative, diuretics and several health benefits. The aim of the present study was to investigate the influence of methanol extract of tiger nut on the male reproductive pathology of chronic lead poisoning in Red Sokoto buck. The tiger nut was extracted using 95% methanol by cold extraction method. Four adults Red Sokoto bucks (12 to 25 kg) were randomly grouped into four. Group I was administered distilled water (200 mL). Group II was administered lead acetate (200 mg/kg) only. Group III was administered methanol extract of tiger nut (200 mg/kg) and lead acetate (200 mg/kg). Group IV was administered tiger nut (200 mg/kg) only. Evaluation of semen characteristics (semen motility, semen concentration, ejaculate volume and semen pH) were determined by standard method. The serum testosterone changes were determined using commercial kits. The lead acetate (200 mg/kg) group II showed decreased semen characteristics parameters while tiger-nut (LA + TN) group III showed improved values of the semen characteristics. However, the semen characteristics values on the distilled water (DW) group I and sole tiger nut (TN) group IV showed a good semen characteristics values. In conclusion the methanol extract of tiger nut contained antioxidant properties that significantly influence a protective role in ameliorating the pathological effect of lead poisoning in male reproductive pathology in Red Sokoto goat.