Browsing by Author "Bamidele, Opeyemi F"

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    A clinicopathological review of colonic polyps in a tertiary Hospital in North Central Nigeria
    (Faculty of Medicine, Omdurman Islamic University, 2018) Bojuwoye, Matthew Olumuyiwa; Olokoba, Abdulfatai Bamidele; Ogunmodede, James Ayodele; Agodirin, Sulaiman Olayide; Ibrahim, Olatunde O. Kazeem; Adeyeye, Ademola A; Bamidele, Opeyemi F; Ogunlaja, Olumuyiwa Ayotunde; Okonkwo, Kenechukwu C; Aliyu, Aminu Mansa
    Background: Colorectal polyps, especially adenomas, are known as precursors of colorectal carcinomas. This study was aimed at determining the prevalence and histopathologic characteristics of colonic polyps among Nigerians that underwent colonoscopy at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. The authors also determined the polyp detection rate and adenoma detection rate. Materials and Methods: This was a hospital-based cross-sectional study of all colonoscopy examinations performed at the University of Ilorin Teaching Hospital, Ilorin from March2013 to September2017. The endoscopy register was reviewed, and patients’ biodata, indications for colonoscopy and colonoscopic findings were recorded on a proforma. The histopathologic reports of the polyps were also retrieved and their diagnosis confirmed. Results: A total of 289 patients had colonoscopy carried out on them. The age of the patients ranged from 14 to 90 years with a mean ± SD of 57.0 ± 15.3 years and a median age of 58years. There were 178(61.6%) males and 111 (38.4%) females giving a M:F ratio of 1.6:1. The indications for colonoscopy were rectal bleeding124(42.9%); suspected colorectal cancer 67(23.2%); abdominal pain 22 (7.6%); chronic diarrhea 18 (6.2%); surveillance colonoscopy 12 (4.2%); constipation 11(3.8%); change in bowel habit 9(3.1%); occult bleeding 6(2.1%); others 20(6.9%). Endoscopic findings were normal findings 89(30.8%); hemorrhoids 88 (30.4%); colonic polyps 50 (17.3%); diverticulosis 34 (11.8%); rectal cancer 29 (10.0%); colon cancer 24 (8.3%); colitis 19 (6.6%); others 13 (4.5%). The findings were not mutually exclusive. The diagnostic yield was 69.2%. The overall polyp detection rate was 17.3%. Of the 50 patients with polyps, 33 (66.0%)were males (p=0.481). The adenoma detection rate was 4.8%. Conclusion: The authors conclude that their observed polyp detection rate is consistent with the estimated rates for Africa. Rectal bleeding and adenomatous polyps were the commonest presentation and histopathologic finding, respectively
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    A STUDY OF THE CLINICAL PROFILE OF PATIENTS WITH HEPATOCELLULAR CARCINOMA IN ILORIN
    (The Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), 2020) Olokoba, Abdulfatai Bamidele; Bojuwoye, Matthew Olumuyiwa; Ogunmodede, James Ayodele; Bamidele, Opeyemi F; Okonkwo, K.C.; Aliyu, Aminu Mansa; Ogbu, Lawrence O.
    Background: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the sixth most common cancer worldwide. Despite being the 6th most common cancer it is the second leading cause of cancer related deaths. It is a major cause of cause of morbidity and mortality in Nigeria. Aim: To study the symptom profile and the prevalence of hepatitis B and C viral infection among patients with HCC in University of Ilorin Teaching Hospital (UITH), Ilorin. Methodology: This was a cross-sectional study of patients with HCC managed at the study center from January 2013 to December 2017. The diagnosis of HCC was made based on the symptoms, physical examination and radiological findings. A structured proforma was used to obtain socio-demographic, clinical presentation and laboratory data from patients who met our inclusion criteria. The data obtained was analyzed using the statistical package for social sciences version 22. Results: A total of 109 HCC patients whose ages ranged from 23-89 years with a mean age (SD) of 45.3 (14.0) years were studied. Eighty-two (75.2%) of these were males and the < 45 years age group had the highest frequency of 57 (52.3%). Weight loss 100 (91.7%), abdominal swelling 98 (89.9%) and abdominal pain 96 (88.1%) were the most prevalent presenting complaints. Jaundice 47 (43.1%), wasting of the small muscles of the hand 35 (32.1%), sparse axillary hair 25 (22.9%) and finger clubbing 24 (22.0%) were the prevailing stigmata of chronic liver disease whereas liver tenderness 85 (75.2%), irregular liver surface 79 (72.5%), hard liver 64 (58.7%) and ascites 65 (59.6%) were the commonest findings on abdominal examination. These were not mutually exclusive. The prevalence of hepatitis B and C among the patients with HCC was 56.9% and 3.7% respectively. Conclusion: HCC is more prevalent among young persons aged < 45 years and among males in UITH, Ilorin. Weight loss, abdominal pain and swelling are the commonest presentation. The prevalence of hepatitis B infection among them is high whereas that of hepatitis C is low.
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    Gastric Adenomyoma: An uncommon cause of dyspepsia and a rare endoscopic finding
    (Faculty of Medicine, Omdurman Islamic University, Sudan., 2020) Bamidele, Opeyemi F; Bojuwoye, Matthew Olumuyiwa; Lawal, Mudashiru; Bello, Ruth Adabe
    Background: Gastric adenomyoma (GA) is a rare benign lesion comprising of ducts and glands embedded in smooth muscle stroma. Thirty-seven (37) cases of GA were identified until 1993, however, only 15 cases are said to have been reported from 1993 to 2016. Oesophagogastroscopy has been widely used in evaluating GA. However, the diagnosis of GA remains exclusively histological. Case: We report a 26-year-old Nigerian woman who presented with recurrent dyspepsia with her endoscopic findings suggestive of GA. GA was confirmed by histology, and she was managed conservatively. Conclusion: This report will contribute to creating awareness of this uncommon condition and also reminding physicians in considering GA as a possible differential of dyspepsia
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    Oesophageal intramural pseudodiverticulosis: a rare endoscopic finding
    (Ghana Medical Association, 2019) Bamidele, Opeyemi F; Olokoba, Abdulfatai Bamidele; Bojuwoye, Matthew Olumuyiwa; Barde, Amanda A
    Oesophageal intramural pseudodiverticulosis is an uncommon condition, characterized by multiple small rounded cavities seen in the oesophageal wall during oesophagogastroduodenoscopy. It is often associated with gastro-oesophageal reflux disease, achalasia, oesophageal candidiasis and diabetes mellitus. We report a 40 year old Nigerian man who presented with recurrent dysphagia and endoscopic findings typical of oesophageal intramural pseudodiverticulosis. The patient was managed medically with resolution of the dysphagia. This report highlights the occurrence of this rare and benign cause of dysphagia in Nigeria.
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    Prevalence of minimal hepatic encephalopathy among patients with chronic liver disease in Ilorin, Nigeria
    (Ghana Medical Association, 2019) Bamidele, Opeyemi F; Olokoba, Abdulfatai Bamidele; Bojuwoye, Matthew Olumuyiwa; Akintayo, Richard O; Bamidele, Oluwakemi
    Background: Minimal Hepatic encephalopathy is the mildest form of Hepatic Encephalopathy which presents with significant cognitive impairment and affectation of activities of daily living. The literature is scanty on the prevalence of minimal hepatic encephalopathy in Nigerians with chronic liver disease. Aim: This study aimed at determining the prevalence of minimal hepatic encephalopathy among patients with chronic liver disease using neuro-psychometric tests. Methods: The study was a hospital-based cross-sectional study carried out at the University of Ilorin Teaching Hospital, Ilorin from February 2015 to February 2016. Chronic liver disease was diagnosed with the presence of peripheral stigmata of liver disease, liver biochemistry, prothrombin time, and sonographic findings in keeping with liver disease. Minimal hepatic encephalopathy was diagnosed using number connection tests-A and B for patients who were educated while Line tracing test and constructional dyspraxia were used for patients without any formal education. Data obtained were analysed using Statistical Package for the Social Sciences (SPSS) version 20 computer software package. Results: Sixty-four patients with chronic liver disease were recruited. The mean age (SD) of the patients was 47.1±14.6 yrs, and the 30-39 and 40-49 yrs age groups each had the highest frequency of 21(32.8%). There were 54 (84.4%) males and 10 (15.6%) females. The prevalence of Minimal Hepatic Encephalopathy was 43.8%. Conclusion: The prevalence of Minimal Hepatic Encephalopathy in this study was similar to previous studies. Significant number of patients with minimal HE were in Child-Pugh class B and C.
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    The Indications and Findings at Colonoscopy in a Tertiary Hospital in North-Central Nigeria: A Seven-Year Review
    (West African College of Physicians, 2021) Bojuwoye, Matthew Olumuyiwa; Bamidele, Opeyemi F; Okonkwo, K; Adeyeye, Ademola A; Aliyu, Aminu Mansa; Oyeleke, Ganiyat Kikelomo; Olokoba, Abdulfatai Bamidele
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    Thrombotic thrombocytopenic purpura as the first presentation in systemic lupus erythematosus
    (Bratislava SAP-Slovak Academic Press s.r.o., 2018) Bamidele, Opeyemi F; Akintayo, Richard Oluyinka; Bojuwoye, Matthew Olumuyiwa; Alabi, Tolulope Oyetunde; Akintayo, Foluke Comfort; Bamidele, Oluwakemi Victoria
    Thrombotic thrombocytopenic purpura (TTP) is an uncommon, life-threatening disease characterized by severe thrombocytopenia, microangiopathic haemolytic anaemia, neurologic abnormalities, renal insufficiency, and fever commonly associated with infections, malignancy, drugs, and autoimmune diseases. Coexistence of TTP with systemic lupus erythematosus (SLE) is extremely rare, and the emergence of the full manifestation of SLE starting with TTP is even rarer. Black people due to genetic risk factors are at increased risk of TTP. In the present article the authors describe the case of a Nigerian woman who developed classical features of TTP as the first manifestation of SLE. The patient’s condition was stabilized after treatment with intravenous pulses of methylprednisolone and subsequently on oral prednisolone and hydroxychloroquine treatment.