Browsing by Author "Baba, A.A."
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Item Chemical Hydration by Acid Leaching of a Brand of Cement in Nigerian Market(2011) Baba, A.A.; Adekola, F.A.; Shobande, O.E.; Ghosh, M. K.; Ayinla, K.I; Adebayo, S. A.In this wok, experiment on chemical hydration by acid leaching from a brand of cement in Nigerian market has been studied the physic-chemical characterization of the sample by inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and X-ray diffraction (XRD) has been examined. The influence of acid concentration and system temperature on the dissolution rates has been investigated. The dissolution rates are greatly influenced by acid concentration and reaction temperature. The dissolution investigations gave rise to activation energy value of 26.3 kJ/mol, which affirmed the diffusion reaction mechanism. Also, about 4.13 s-1 and 0.98 were obtained as the system’s Arrhenius constant and reaction order for the dissolution process, respectively.Item Comparism of antimicrobial and wound healing properties of Albizia chevalieri and Commiphora kerstingii in rabbit(Nigerian Veterinary Medical Association, 2018-10) Olusanmi, F.T.; Adeyaju, J.B.; Fadason, S.T.; Awasum, C.A.; Ambali, S.F.; Abidoye, E.O.; Abdulrahman, M.; Baba, A.A.; Daodu, O.B.Wound treatment and wound healing have often been made difficult and complicated by the presence of infective microbial particles. The aim of this study was to investigate the wound healing and antimicrobial activities of methanol leaf extracts of the plants Albizia chevalieri and Commiphora kerstingii. Extraction of the dried pounded plants was done using methanol as solvent in Soxhlet apparatus (Quick fit, England). Preliminary phytochemical screening of the plant extracts was carried out using standard methods. Twelve rabbits of both sexes were divided into four groups (A, B, C, and D) each consisting of three rabbits. Bilateral full thickness excision wounds measuring 2cm x 1cm were surgically induced on the dorsum (lumbar region) of each rabbit. Rabbits in the group A were treated with the vehicle petroleum jelly (Unilever PLC) (Negative control), while those in group B were treated with 2%w/w penicillin ointment (positive control). Rabbits in groups C and D were treated with the extracts of A. chevalieri (1g/10g petroleum jelly (AC) and C. kerstingii extract (1g/10g petroleum jelly (CK) respectively. The wounds were treated every 48 hours for three weeks and evaluated for exudation in terms of rate and nature, wound contraction and epithelization. The antimicrobial activities of the methanol leaf extracts of the plats were determined against S. aureus (Gram positive organism) and E. coli (Gam negative organism) using agar gel diffusion methods. The extracts of A. chevalieri and C. kerstingii contain the following metabolites: flavonoids, tannins, alkaloids, saponins, cardiac glycosides, steroids, triterpenes and carbohydrates. The results showed a consistent decline in bacterial colony count in all the groups irrespective of the treatment formulation used. Exudation decreased drastically with treatment in Groups C and D, while animals in groups A and B showed moderate production of exudate up till the 7th day of treatment which gradually declined between the 19th and 13th day. Wounds of animals in Group C showed faster rate of wound contraction, decreased epithelization period and increased healthy granulation tissue formation. This was followed by wounds of animals in group B, wounds of animals in group D and lastly wounds of animal in Group A. No antimicrobial effect was shown by wounds of Group A against any of the tested microorganisms. The 2% w/w penicillin ointment showed remarkable activity against the Gram-positive S. aureus (28mm) and Gram-negative E. coli (26 mm). A. chevalieri extract exhibited tremendous activity against the Gram-positive S. aureus (30 mm) but no effect against Gram negative E. coli, while C. kerstingii extract showed remarkable activity against the Gram-negative E. coli (24 mm) but no effect against Gram-positive S. aureus. The result of this study showed that methanol leaf extract of the plant A. chevalieri was more effective, followed by methanol leaf extract of C. kerstingii and the influence on wound healing was to a large extent comparable to 2% w/w penicillin ointment with no adverse reactions.