Browsing by Author "Aliyu, Aminu Mansa"

Now showing 1 - 6 of 6
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    A clinicopathological review of colonic polyps in a tertiary Hospital in North Central Nigeria
    (Faculty of Medicine, Omdurman Islamic University, 2018) Bojuwoye, Matthew Olumuyiwa; Olokoba, Abdulfatai Bamidele; Ogunmodede, James Ayodele; Agodirin, Sulaiman Olayide; Ibrahim, Olatunde O. Kazeem; Adeyeye, Ademola A; Bamidele, Opeyemi F; Ogunlaja, Olumuyiwa Ayotunde; Okonkwo, Kenechukwu C; Aliyu, Aminu Mansa
    Background: Colorectal polyps, especially adenomas, are known as precursors of colorectal carcinomas. This study was aimed at determining the prevalence and histopathologic characteristics of colonic polyps among Nigerians that underwent colonoscopy at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. The authors also determined the polyp detection rate and adenoma detection rate. Materials and Methods: This was a hospital-based cross-sectional study of all colonoscopy examinations performed at the University of Ilorin Teaching Hospital, Ilorin from March2013 to September2017. The endoscopy register was reviewed, and patients’ biodata, indications for colonoscopy and colonoscopic findings were recorded on a proforma. The histopathologic reports of the polyps were also retrieved and their diagnosis confirmed. Results: A total of 289 patients had colonoscopy carried out on them. The age of the patients ranged from 14 to 90 years with a mean ± SD of 57.0 ± 15.3 years and a median age of 58years. There were 178(61.6%) males and 111 (38.4%) females giving a M:F ratio of 1.6:1. The indications for colonoscopy were rectal bleeding124(42.9%); suspected colorectal cancer 67(23.2%); abdominal pain 22 (7.6%); chronic diarrhea 18 (6.2%); surveillance colonoscopy 12 (4.2%); constipation 11(3.8%); change in bowel habit 9(3.1%); occult bleeding 6(2.1%); others 20(6.9%). Endoscopic findings were normal findings 89(30.8%); hemorrhoids 88 (30.4%); colonic polyps 50 (17.3%); diverticulosis 34 (11.8%); rectal cancer 29 (10.0%); colon cancer 24 (8.3%); colitis 19 (6.6%); others 13 (4.5%). The findings were not mutually exclusive. The diagnostic yield was 69.2%. The overall polyp detection rate was 17.3%. Of the 50 patients with polyps, 33 (66.0%)were males (p=0.481). The adenoma detection rate was 4.8%. Conclusion: The authors conclude that their observed polyp detection rate is consistent with the estimated rates for Africa. Rectal bleeding and adenomatous polyps were the commonest presentation and histopathologic finding, respectively
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    A STUDY OF THE CLINICAL PROFILE OF PATIENTS WITH HEPATOCELLULAR CARCINOMA IN ILORIN
    (The Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), 2020) Olokoba, Abdulfatai Bamidele; Bojuwoye, Matthew Olumuyiwa; Ogunmodede, James Ayodele; Bamidele, Opeyemi F; Okonkwo, K.C.; Aliyu, Aminu Mansa; Ogbu, Lawrence O.
    Background: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the sixth most common cancer worldwide. Despite being the 6th most common cancer it is the second leading cause of cancer related deaths. It is a major cause of cause of morbidity and mortality in Nigeria. Aim: To study the symptom profile and the prevalence of hepatitis B and C viral infection among patients with HCC in University of Ilorin Teaching Hospital (UITH), Ilorin. Methodology: This was a cross-sectional study of patients with HCC managed at the study center from January 2013 to December 2017. The diagnosis of HCC was made based on the symptoms, physical examination and radiological findings. A structured proforma was used to obtain socio-demographic, clinical presentation and laboratory data from patients who met our inclusion criteria. The data obtained was analyzed using the statistical package for social sciences version 22. Results: A total of 109 HCC patients whose ages ranged from 23-89 years with a mean age (SD) of 45.3 (14.0) years were studied. Eighty-two (75.2%) of these were males and the < 45 years age group had the highest frequency of 57 (52.3%). Weight loss 100 (91.7%), abdominal swelling 98 (89.9%) and abdominal pain 96 (88.1%) were the most prevalent presenting complaints. Jaundice 47 (43.1%), wasting of the small muscles of the hand 35 (32.1%), sparse axillary hair 25 (22.9%) and finger clubbing 24 (22.0%) were the prevailing stigmata of chronic liver disease whereas liver tenderness 85 (75.2%), irregular liver surface 79 (72.5%), hard liver 64 (58.7%) and ascites 65 (59.6%) were the commonest findings on abdominal examination. These were not mutually exclusive. The prevalence of hepatitis B and C among the patients with HCC was 56.9% and 3.7% respectively. Conclusion: HCC is more prevalent among young persons aged < 45 years and among males in UITH, Ilorin. Weight loss, abdominal pain and swelling are the commonest presentation. The prevalence of hepatitis B infection among them is high whereas that of hepatitis C is low.
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    Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature
    (African field epidemiology network (AFENET), 2018) Bojuwoye, Matthew Olumuyiwa; Olokoba, Abdulfatai Bamidele; Ogunlaja, Olumuyiwa Ayotunde; Agodirin, Sulaiman Olayide; Ibrahim, Olatunde O. Kazeem; Okonkwo, Kenechukwu C; Aliyu, Aminu Mansa
    Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin. Two cases were clinically diagnosed in our facility. They both presented with gastrointestinal bleeding and numerous rectal and colonic polyps were identified at colonoscopy. Histological examination of the polyps in both cases revealed features in keeping with adenomatous polyps. This report highlights the occurrence of this precancerous condition.
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    INDICATIONS AND POSITIVITY RATES OF 14C-UBT FOR HELICOBACTER PYLORI DETECTION
    (Kenya Medical Association, 2023) Bojuwoye, Matthew Olumuyiwa; Agede, Olalekan A; Ilesanmi, Omotoyosi Nike; Aiyedun, Olawale Stephen; Suleiman, S.T.; Aliyu, Aminu Mansa; Ojimi, O.O.
    Background: In order to diagnose H. pylori infection, the 14C-UBT (14 Carbon Urea Breath Test) has become a popular non-invasive diagnostic method. Understanding the 14C-UBT indications and the associated positivity rates can offer helpful insights on the frequency of H. pylori infection in various clinical settings. The purpose of this study was to determine the prevalence of H. pylori infection as determined by the 14C-UBT and to analyze the causes of the patterns seen in various clinical presentations. Methods: From 2012 through 2019, pertinent data, including biodata, symptoms, and test results, were obtained from the authorized register. Statistical software for social sciences (SPSS) v22 was used to examine the data once they had been entered into a spreadsheet. Results: The findings revealed that the prevalence of H. pylori infection was highest in people between the ages of 41 and 50, with 45 of 167 patients testing positive. The most frequent reason for performing the 14C-UBT was dyspepsia, with a high positive rate of almost 63.29%. This result can be related to the recognized relationship between H. pylori and chronic gastritis and peptic ulcer disease, both of which are known to produce dyspeptic symptoms. Conclusion: In addition to highlighting dyspepsia as the most frequent indication for the 14C-UBT, this study sheds light on the greater frequency of H. pylori infection in the 41–50-year age group. The diagnosis and treatment of illnesses linked to H. pylori can be aided by understanding these patterns and relationships, ultimately leading to better patient care.
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    Spectrum of oesophagogastroduodenoscopy findings in patients presenting with upper gastrointestinal bleeding in a tertiary hospital in Ilorin
    (The Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), 2023) Bojuwoye, Matthew Olumuyiwa; Obateru, Olusegun Ayodeji; Aliyu, Aminu Mansa; Okonkwo, Kenechukwu Chukwuemeka; Ogbu, Lawrence Ogbonnaya; Ojimi, Olajumoke Olubusayo; Arinde Olufemi; Safiu, Kamorudeen Ishola; Olokoba, Abdulfatai Bamidele
    Background: Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Oesophagogastroduodenoscopy (OGD) is an invaluable tool in the investigation and management of UGIB. Aim: We studied the spectrum of endoscopy findings among patients who were referred for OGD on account of UGIB. Methodology: This was a cross-sectional study of patients who had OGD done at the University of Ilorin Teaching Hospital on account of UGIB from year 2010 to 2022. Endoscopies were performed as per the standard protocol with diagnosis based on accepted criteria. Data were retrieved from the endoscopy register, entered into a spreadsheet, and analyzed using the Statistical Package for Social Sciences (SPSS) version 22. Categorical variables were compared using a Chi-square test and statistical significance set at P < 0.05. Results: A total of 1438 patients (mean age: 51.0 ± 16.4 years; age range, 10–100 years; 730 [50.8%] females) were included. Of these patients, 280 (19.5%) presented with UGIB. Peptic ulcers disease (PUD) 68 (24.3%) followed by gastritis 50 (17.9%), esophageal/gastric varices 42 (15.0%), gastroduodenitis 20 (7.1%) and gastric tumors 18 (6.4%) were the commonest causes of UGIB in the study population. Of the 68 cases of PUD, 43 were duodenal ulcers whereas 25 were gastric ulcers. The mean age of patients with UGIB was 51.0 ± 20.0 years and it was more common in males 187 (66.8%); P < 0.05. Conclusion: UGIB was more common in males and the most common cause of UGIB in our study population was PUD
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    The Indications and Findings at Colonoscopy in a Tertiary Hospital in North-Central Nigeria: A Seven-Year Review
    (West African College of Physicians, 2021) Bojuwoye, Matthew Olumuyiwa; Bamidele, Opeyemi F; Okonkwo, K; Adeyeye, Ademola A; Aliyu, Aminu Mansa; Oyeleke, Ganiyat Kikelomo; Olokoba, Abdulfatai Bamidele