Browsing by Author "Alabi, K.O"

Now showing 1 - 3 of 3
  • Item
    Reference values for the six-minute walk test in Nigerian adolescents aged 10 to 18 years
    (College of Health Sciences, Osun State University, 2019) Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Akintade, O.O; Suberu, H.D.; Issa, A; Alabi, K.O
    Objective: To determine baseline six-minute walk distance in Nigerian adolescents and establish its relationship with age, gender and anthropometric parameters. Methods: One hundred and eighty healthy adolescents (10 – 18 years) were recruited from three schools. Six-minute walk test was conducted as described by the American Thoracic Society. Demographic and anthropometric characteristics were related to achieve six-minute walk distance. Amathematical formula for predicting six-minute walk distance was generated. Results: The mean ± SD six-minute walk distance was 590.1 ± 72.02 m and was significantly longer in males (p= 0.001) among adolescents aged 10- 16 years. Age was the only characteristic significantly associated with six-minute walk distance following multiple linear regression analyses. The formulae, [six-minute walk distance = 317.3 + 21.5 x age (years) in males and 117 + 33.0 x age (years) in females] closely approximated to measured six-minute walk distance. Conclusion: This study has derived reference values for 6-minute walk test in adolescents; the use of these reference values should consider age and gender variations.
  • Item
    Relationship Between Microalbuminuria and Risk Factors for Cardiovascular Diseases Among Secondary School Student in Ilorin, Nigeria
    (Nepal Paediatric Society, Nepal, 2021) Alabi, K.O; Kayode-Alabi, T.F; Ibrahim, O.R.; Issa, H; Abdulkadir, Mohammed Baba; Ernest, S.K.; Ojuawo, A.I
    Introduction: Globally, cardiovascular diseases (CVDs) are the leading causes of deaths with more than half due to coronary heart disease linked with the development of atherosclerosis. Hypertension (HTN) and obesity are leading risk factors for atherosclerotic CVDs, presence of which is predicted by microalbuminuria (MA). We wanted to evaluate the relationship between microalbuminuria and risk factors for CVDs (obesity, overweight, pre-hypertension and hypertension) among secondary school students in Ilorin, North central Nigeria. Methods: We conducted a descriptive, cross-sectional study from December 2017 to March 2018 among secondary school students. We recruited 584 students, aged 10 to 18 years from 14 schools across the three Local Government Areas (LGAs) in Ilorin. We measured their blood pressure and anthropometrics following standard protocols and determined microalbuminuria in their early morning urine using Microalbumin 2-1 Combo strip and spot urinary albumin - creatinine ratio. Results: The prevalence of MA was 30.1%. MA was more common in obese and hypertensive adolescents (p < 0.001 and p < 0.01 respectively). Occurrence of MA correlated strongly with subject’s weight (r = 0.790, p = 0.004, p < 0.01); systolic blood pressure (r = 0.884, p = 0.001, p < 0.01) and body mass index (r = 0.710, p = 0.001, p < 0.01). Independent predictors of MA were obesity, adjusted odds ratio (aOR) 4.9, (95% CI 1.124, 20.913), overweight (aOR 3.6, 95% CI 1.184, 10.174), older age (aOR 1.1, 95% CI 1.007, 1.219) and presence of systolic hypertension (aOR 3.1, 95% CI 1.903, 5.042). Conclusions: This study shows a high prevalence of MA among the adolescents. CVDs risk factors predictive of MA are overweight, obesity, systolic hypertension and older age.
  • Item
    Relationships between cardiovascular signs and neurological signs in asphyxiated neonates in Ilorin, North Central Nigeria
    (Makarere University Medical School, Kampala, Uganda, 2021) Issa, A; Abdulkadir, Mohammed Baba; Adesiyun, OO; Owolabi, B; SUberu, H; Alabi, K.O; Bakare, R.R.
    Background: Perinatal asphyxia is a condition associated with multiple organ dysfunctions inclusive of cardiovascular dys function. Neurologic predictors of survival have been studied, but little has been reported regarding cardiovascular signs and their role in determining outcome in asphyxia. Objective: The study aimed to determine the relationship between cardiovascular signs and outcomes in asphyxiated new borns with hypoxic ischaemic encephalopathy. Methods: This was a cross sectional study involving asphyxiated new-born babies recruited within the first 24 hours of life. Hypoxic ischaemic encephalopathy staging was done using Sarnat and Sarnat staging. All patients had a detailed cardi ovascular examination on admission, after initial resuscitation (30 – 60 minutes) into admission, and were followed till final outcome: discharge or death. Results: Eighty-five asphyxiated new-borns with HIE were studied over seven months. Abnormal cardiovascular-related signs identified in the patients included respiratory distress (64.7%), small volume pulse (57.6%), hypotension (52.9%), hy poxemia (48.2%) and shock (32.9%). Five babies died. None of the clinical signs had a significant relationship with mortality. Conclusion: Abnormal cardiovascular signs increased with the progression of HIE staging but had no relationship with mortality.