Browsing by Author "Afolabi, J. K."

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    Intelligence Quotient of Neurologically Impaired Children Attending Neurology Clinic in a Nigerian Tertiary Institution.
    (College of Medicine and Allied Health Sciences, University of Sierra Leone, 2018-01) Adeboye, M. A. N.; Katibi, O. S.; Adegboye, O. A.; Ojuawo, A.; Afolabi, J. K.; Buhari, O. I. N.; Adegunloye, O. A.; Bello, S. O.; Omefa, P. N.; Abdulazeez, T. A.
    Background: The need to identify the intellectual capability of Neurologically impaired children dictates their educability which can be estimated through their intelligence quotient (IQ). Draw-a-man test for IQ estimation is available, easy and has been validated in Nigeria. Method: Through a prospective, cross-sectional study that lasted 12 months (January-December, 2011), children aged 4 years and above attending neurology clinic were recruited once they have no severe motor or sensory limitations affecting their upper limbs, and can obey instruction to draw a person. Anthropometry was carried out on them and they were comfortably seated to draw a person. The parents or care givers were instructed not to make any suggestion or hint to them and no time limit was given. Their drawings were assessed using the 52 parameters of Ziler and interpreted accordingly. Ethical procedures were adhered to. Analysis was done using SPSS version 16 and an interactive calculation tool for chi-square tests of goodness of fit and independence. Results: Seventy-five (45 male, 30 female) children met the inclusion criteria. Their clinical conditions were Epilepsy 48 (64%), Cerebral Palsy 6 (8%), ADHD 5 (6.7%), Down Syndrome 4 (5.3%), Speech/Hearing impairment 3 (4.0%), Hypothyroidism 2 (2.7%) and 7 (9.3%) others. Their ages ranged from 4 years to 16 years (mean±SD = 9.7± 3.8 years). Their IQ distribution were Normal 4 (5.3%), Borderline 12 (16.0%), Mild Mental Retardation 16 (21.3%), Moderate Mental Retardation 19 (25.3%), Severe and Profound Mental Retardation 24 (32.0%) with no significant difference in relation to their birth order. Conclusions: Ninety-six percent of the study population had IQ below normal. Epilepsy was the commonest condition seen in the Paediatric Neurology clinic and all categories of IQ are seen among children with epilepsy.
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    Normal CD4+ Cell Count Range Amongst Healthy Nigerian Population In Ilorin,
    (International Association of Providers of AIDS Care., 2014) Afolabi, J. K.; Fadeyi, A; Desalu, O. O.; Durotoye, I. A.; Fawibe, A. E.; Adeboye, M. A. N.; Olawumi, H. O.; Babatunde, A. S.; Ernest, S. K.; Aderibigbe, S. A.; Saadu, R.; Salami, A. K.; Aboyeji, A. P.
    Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm 3 (19%-48%) and for children was 582 to 3652 cells/mm 3 (17%-50%). CD4 count and percentage of CD4 were significantly (P 1⁄4 .001) higher in females than in males, and the CD4 count declined significantly with increasing age (r 1⁄4 .174, P .0001). The percentage of CD4 count shows less variation with age (r 1⁄4 .051, P 1⁄4 .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 + 260) than that of the national reference values of 847.0 + 307.0 cells/mm 3 (P 1⁄4 .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.
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    Reference Values of Haematological Parameters of Healthy Adults in the North Central Zone of Nigeria
    (Kenya Medical Association, 2015) Olawumi, H.O; Durotoye, I. A.,; Afolabi, J. K.; Fadeyi, A.,; Desalu, O.O.,; Aderbigbe, S.A.,; Babatunde, A.S.,; Ernest, S.K.,; Fawibe, A.E.,; Salami, A.K.,; Saadu, R.,; Adeboye, M.A.N.,; Aboyeji, A.P.
    Background: Haematological parameters differ from one population to another due to several factors. To determine the clinical implication of the blood parameters of an individual in the state of health or disease, we need to have the knowledge of the normal reference range for that locality. Objectives: To determine the reference values of haematological parameters of apparently healthy adults in Ilorin. Design: A descriptive cross sectional study. Setting: Ilorin, North Central zone of Nigeria Subjects: Nine hundred and ten (443 males and 467 females) randomly selected normal, HIV negative individuals aged 18-65 years Results: The red blood cell count, Haemoglobin concentration, PCV and MCHC were significantly higher among males than females while the platelet count, total WBC count and absolute neutrophil count were significantly higher in females than in males. There was however no significant gender difference in the values of MCV, MCH and absolute lymphocyte count. The normal reference values obtained in this study were notably different from those that are used currently in the hospital. Conclusion: The normal reference value obtained in this study was notable different from those that are currently used in the hospital. These findings will have clinical implications regarding the adjustment of our current reference values and definitely add value to the management of patients in this part of the country. INTRODUCTION A full blood count is one of the most frequently requested investigations for routine medical checkup and preliminary investigation in the diagnosis of many diseases in every field of Medicine. It is also a common investigation used to monitor the treatment of several diseases especially in patients on cytotoxic drugs (1). The parameters in a full blood count also known as haematological parameters are affected by many different factors such as age, gender, race, altitude, exercise, pregnancy