Browsing by Author "Adesina, K.T."
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Item Autologous blood donations and transfusions among patients undergoing elective orthopaedic, gynaecologic and elective caesarean section at a Tertiary Hospital in North Central Nigeria(Kenya Medical Association, 2018) Shittu, A.O.; Olawumi, H.O.; Adesina, K.T.; Babalola, O.M.; Ibraheem, G.H.; Babatunde, A.S.; Olatinwo, A.W.O.ABSTRACT Introduction: Allogeneic donor blood is becoming increasingly costly, scarce and associated with multiple risks; there is need for more conservative transfusion strategies, one of which may be adoption of Autologous Blood Donation and Transfusions (ABDT). Despite increased acceptance of ABDT by clinicians and patients in most developed world, awareness in this part of the world is still low. Materials and methods: this is a cross sectional survey of knowledge and acceptance of ABDT by patients scheduled for elective orthopaedic, gynaecologic and elective caesarean section surgeries using structured interviewer administered questionnaire on socio-demographics, clinical presentations, knowledge of blood donations and transfusions, and acceptance of ABDT. The study population comprised of 171 subjects. Results: Gynaecologic/obstetric patients were 120 (70.2%) while 51 (29.8%) of the subjects were Orthopaedic patients. Majority (43.95%) were within the age range 31-45 years, 38.6% were less than 31 years while 17.5% were older than 45 years. Females constituted the larger proportion (77.2%). Twenty one (12.3%) subjects had donated blood in the past, 45 (26.3%) had previous blood transfusions and 30 (17.5%) had knowledge of ABDT. Eight one (47.4%) of all subjects accepted ABDT for the scheduled surgeries while 123 (71.9%) subjects accepted to be voluntary blood donors after surgery. Pre-deposit is the commonest form of ABDT preferred by the subjects (66%), followed by Haemodilution (28%) and Cell salvage (6%). February 2018 EAST AFRICAN MEDICAL JOURNAL 1215 significant number of the subjects who accepted ABDT were ready to become voluntary blood donors after surgery (90.1%). Conclusion: Acceptance rate as high as 47.4% was recorded in this study despite low awareness. This is higher than what was reported by most authors’ locally but similar to the findings from Europe and Asia. Pre-deposit form was the commonest ABDT acceptable to these patients. Improving awareness on ABDT will boost voluntary blood donations and improve blood transfusion safety.Item Haematological Parameters of Normal Pregnant Women During Antenatal Clinic Booking in Ilorin, North Central Nigeria(Ambrose Alli University, 2017) Babatunde, A.S.; Olawumi, H.O.; Durotoye, I.A.; Shittu, A.O.; Adesina, K.T.; Sani, M.A.; Nyamgee, AAlterations in the values of some haematological parameters like packed cell volume and haemoglobin concentration during pregnancy have been reported to significantly influence pregnancy outcome. The aim of this study was to determine the values of haematological parameters in apparently healthy pregnant women during the antenatal clinic booking visit at the University of Ilorin Teaching Hospital, Ilorin, North central Nigeria. A total of 298 apparently healthy pregnant women who presented for antenatal care booking and satisfied the inclusion criteria were included in the study. There were 64 (21.5%) women in first trimester, 146 (49.0%) women in second trimester and 88 (29.5%) in third trimester; and were aged between 22 and 42 years. Packed cell volume, haemoglobin concentration, Red cell count, mean haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin concentration, Total white blood cell count and differentials, Platelet count and erythrocyte sedimentation rate were carried out in the subjects. The overall mean values and SD of the pregnant women for the haematological parameters were as follows: PCV (32.76±2.18%), Hb (10.82±0.77g/dl), RBC (3.87±2.32 x1012/L), MCH (28.08±2.06 pg), MCV (85.16±5.82 fl), MCHC (33.01±1.05 g/dl), TWBC (7.35±2.62 x109/L), Platelet count (192.15±62.80 x109/L) and ESR (34.07±16.85 mm/hr). There were statistically significant differences in the mean values of PCV, MCH and MCV with increasing gestational age (p<0.05). Conclusion: The present study provides a baseline data on the haematological values in pregnancy in the North central zone of the country on which further large scale studies in future may be based. This study will also be of immense benefit in the monitoring of pregnant women to determine those at risk for timely intervention thereby improving pregnancy outcome.Item The Impact of Body Mass Index on haematological parameters of pregnant women at booking in Ilorin, Nigeria(University of Ilorin, 2013) Adesina, K.T.; Balogun, O.R.; Aderibigbe, A.S.; Babatunde, A.S.; Sanni, A.; Olarinoye, A.O.; Ezeoke, G.G.ABSTRACT: Background: Pregnancy is associated with physiological changes that affect almost all of the systems in the body, including weight gain; these changes accommodate the demands of the feto-placental unit. Therefore, hematological parameters in pregnancy may not be comparable with those of non-pregnant women. Methodology: A total of 500 pregnant women were consecutively recruited at booking, and 465 met the inclusion criteria. Their blood samples were analyzed for some blood indices, which were compared with their body mass indices and sociodemographic characteristics. Results: The mean levels of Mean Corpuscular Volume(MCV) and Mean Corpuscular Hemoglobin Concentration(MCHC) were 82.2 fl ± 8.4 and 34.0 g/dl ± 1.9, respectively, which were within the normal reference values but close to the lower limits. The hemoglobin concentration was low (10.5 g/dl), whereas the erythrocyte sedimentation rate was high (34.1 mm/hr). Hematological parameters were compared by trimesters. MCV and Mean Corpuscular Hemoglobin (MCH) increased across the trimesters, with P values of 0.0007 and 0.011, respectively (P< 0.05). PCV was also inversely proportional to the gestational age (P0.026). There was no statistically significant difference when BMI and hematological parameters were compared (P>0.05), although RBC and PCV values increased as the maternal weight increased, suggesting a probable positive correlation between the red cell count and concentration and body mass index in pregnancy. Conclusion: This study confirmed the hemodilutional effect of pregnancy and suggests a relationship between BMI, RBC and PCV in pregnancy. Body weight may increase the red cell parameters in pregnancy.Item Impact of Malaria Parasitaemia on Haematologic Parameters in Pregnant Women at Booking in Ilorin, Nigeria(Science Alert, 2009) Adesina, K.T.; Balogun, O.R.; Babatunde, A. S.; Sanni, M.A.; Fadeyi, A.; Aderibigbe, S.We determined the pattern of haematological parameters in malaria in pregnancy. Five hundred pregnant women who presented for booking in the antenatal clinic of the University of Ilorin Teaching Hospital, Ilorin, Nigeria were recruited. Their blood samples were analyzed for malaria parasites, MCV, MCHC and MCHC, WBC, absolute RBC count, platelet count, haemoglobin level and PCV. The prevalence of peripheral malaria parasitaemia at booking was 32.4%, out of which 46.9 and 53.1% had moderate and high parasite densities, respectively. Plasmodium falciparum was the only species identified. The MCHC was higher in malaria parasitaemia (34.28 g dL-1±1.72, p = 0.0452) while RBC was higher without parasitaemia (10.46x1012 L-1±1.30, p = 0.01). The WBC in women with high parasite density (7.02x109 L-1) was higher than the value in those with moderate parasite density (6.26x109 L-1) p = 0.03). Asymptomatic Plasmodium falciparum infection in pregnancy is associated with higher MCHC; WBC increases with rise in the parasite density in Ilorin, Nigeria. A rise in MCHC and WBC in pregnancy may indicate malaria.Item Malaria Parasitaemia and Anaemia among First Antenatal Clinic Attendees in Ilorin, Nigeria(Pan Africa Medical Journal, 2010) Fadeyi, A.; Balogun, O.R.; Babatunde, A.S.; Adesina, K.T.; Aderibigbe, S.; Sani, M.A.The burden of malaria and anaemia in pregnancy is unknown in Ilorin, Nigeria despite malaria being threat to 2.4 billion lives world-wide including Nigerians particularly the children and pregnant women. To determine the prevalence of malaria parasitaemia and anaemia in pregnancy among first antenatal clinic attendees at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria, 500 consecutive, consenting pregnant women presenting for antenatal care at UITH, Ilorin for the first time were screened for malaria parasitaemia and anaemia over a 1 year period starting from June 2008. Information about participants’ socio-demographic data, fever, anti-malaria therapy including prophylaxis using intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp/SP) among others were also obtained at recruitment. The prevalence of malaria parasitaemia and anaemia in the women were 32.4% and 25.8 respectively. The women’s age, parity and educational level did not affect either malaria parasitaemia (MP) or mean parasite density (MPD) but gestational age (GA) significantly (F = 6.02, p = 0.002) affected MPD as women in the first trimester (35.7%) were most infected. The mean haemoglobin concentration (MCH) was significantly associated with maternal age (f = 3.33, p = 0.005) and parity ((f – 23.97, p = 0.000), and varied inversely as the MPD. Maternal fever was not a good predictor of MP as only 7 (46.7%) of 162 (32.4%) malaria parasitaemic women were febrile. There was no significant difference (f = 1.4, p = 0.23) in the mean malaria parasite densities of anaemic compared with non-anaemic women but there was significant difference in the prevalence of MP (X2 = 1.135, p = 0.0007549) and anaemia (X2 = 8.634, p = 0.0000) among users and non-users of IPTp/SP. Malaria parasitaemia and anaemia remains a threat in pregnancy in Ilorin, Nigeria with the affected often afebrile. Since users of IPTp/SP in pregnancy were better protected against malaria parasitaemia and anaemia in pregnancy, early antenatal booking and use of IPTp/SP is desired.Item Prevalence of Anaemia among Pregnant Women at Antenatal Care Booking in Ilorin, North Central Nigeria(College of Health Sciences, University of Ilorin, 2017) Babatunde, A.S.; Olawumi, H.O.; Durotoye, I.A.; Shittu, A.O.; Adesina, K.T.; Sanni, M.A.Abstract: Anaemia is a global health problem which commonly affects women and children most especially in the developing countries. Anaemia in pregnancy is the most common haematological condition encountered among pregnant women in most developing countries including Nigeria. This prospective study was carried out to determine the red blood cell indices (PCV, Hb, RBC, MCH, MCV, MCHC) and the prevalence of anaemia among pregnant women attending the University of Ilorin Teaching Hospital, Ilorin. A total of 298 women who presented for booking at the antenatal clinic at different levels of pregnancy were enrolled in the study. There were 64 (21.5%) women in first trimester, 146 (49.0%) women in second trimester and 88 (29.5%) in third trimester The mean age of the women was 25.8±3.2 years, and their ages ranged between 18-42 years. One hundred and eighty pregnant women had haemoglobin concentration < 11.0g/dl giving a prevalence rate of anaemia of 60.4%. Mild anaemia was found in 105 (58.3%), moderate anaemia in 72 (40.0%) and anaemia in 3(1.7%) of the pregnant women. There was significant correlation between anaemia and gestational age, parity and level of education at booking. This study indicated presence of high prevalence of anaemia in pregnancy and there is need for appropriate interventional strategies to be put in place so as to reduce prevalence of anaemia and improve pregnancy outcome in our environment