Browsing by Author "Adekunle, A.S."

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    Cooling potential of formulated bio-quenchant oils on cast Aluminium alloy material.
    (University of Chemical Technology and Metallurgy (UCTM), Sofia, Bulgaria, 2020) Adekunle, A.S.; Adeleke, A.A.; Gbadamosi, T.A.; Nwosu, F.O.; Odusote, J.K.; Omoniyi, P.O.; Popoola, O.T.; Adebiyi, K.A.
    The biodegradable vegetable oil based quenchants can serve as cooling media alternative to that of the toxic non-biodegradable petroleum based mineral oil in a heat treatment of aluminium and its alloy. 70 vol. % of edible vegetable oil are blended with 30 vol. % of Jatropha oil to form bio-quenchant oils for Aluminium (Al)-alloy probe treated at 500oC and soaked for 15 min in a muffle furnace. The cooling potential properties such as the cooling rate, the heat transfer coefficient, the Grossman quench severity and the biot number are investigated. The results obtained show that the blended bleached (BB) melon oil provides the highest cooling rate of 49.30oC s-1, while the blended raw (BR) palm oil ensures the lowest cooling rate of 18.45oCs-1. Heat transfer coefficients of 704.6 Wm-2K-1, 432.3 Wm-2K-1, and 394.4 Wm-2K-1 are exhibited by the blended bleached melon oil, the blended raw melon oil and the blended bleached groundnut oil, respectively. They are found higher than that of a petroleum based mineral oil, which amounts to 68.7 Wm-2K-1. The lowest heat transfer coefficient of 272.11 Wm-2K-1 is obtained in case of using a blended raw palm oil. The quench severity of the blended bleached melon oil, the blended raw melon oil and the blended raw groundnut oil refers to a Grossman H-factor of 1.01 m-1, 0.78 m-1, and 0.67 m-1, respectively. The latter values are higher than that obtained in case of a blended raw palm oil, which is equal to 0.37 m-1. However, the heat flow parameters obtained reveal that the blended bleached and the blended raw melon and groundnut oil can be characterized as fast quenching oils, while the blended bleached and the blended raw palm oil can be characterized as medium quenching oils of results comparable to and even better than those of the industrial petroleum based mineral oil
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    Effects of Ethylacetate Leaf Extract of Annona Muricata on Some Enzymes of Carbohydrate Metabolism in Streptozotocin Induced Diabetes in Male Wistar Rats
    (Nigeria Society of Biochemistry and Molecular Biology, 2022) Lawal, A.Z.,; Abdulrahim H.A.,; Yusuf, A.I.,; Ibrahim, M. &; Adekunle, A.S.
    Diabetes is a chronic metabolic disease of multiple etiologies characterized by high blood sugar levels. The management of diabetes is taken as a global problem and curative treatment is yet to be uncovered. The leaf, root and bark of Annona muricata have been reportedly used locally as an antidiabetic agent. This study aimed to evaluate the effects of ethylacetate leaf extract of Annona muricata (AMLE) on selected enzymes of carbohydrate metabolism in diabetic rat model. Twenty male rats weighing 180 to 220 g were randomly assigned into four groups. Groups A and B were non-diabetic and diabetic rats respectively, treated with 5% dimethyl sulfoxide saline respectively. Groups C and D were diabetic rats treated with 200 mg/kg body weight (b.wt) AMLE and 5 mg/kg b.wt glibenclamide respectively for 14 days. Diabetes was induced by a single dose of 45 mg/kg b.wt streptozotocin (STZ) intraperitoneally. Rats with blood glucose values above 13.9 mmol/l 48 hours after STZ injection were considered diabetic. Animals were sacrificed on day 15 and hepatic activities of glucose-6-phosphate dehydrogenase, glucokinase, glucose-6-phosphatase and lactate dehydrogenase were assayed. The levels of hepatic lactate dehydrogenase, glucose-6-phosphate dehydrogenase and glucokinase activities in AMLE treated diabetic rats were significantly (p˂0.05) reduced compared to untreated diabetic rats. However, the activity of glucose-6-phosphatase was only slightly inhibited in the diabetic rats treated with AMLE. Ethylacetate leaf extract of A. muricata inhibited the activities of glucose-6-phosphatase and lactate dehydrogenase in this study. These findings partially support the use of this plant in the treatment of diabetes.