Browsing by Author "Adegboye, A. A."
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Item EFFECT OF BORASSUS AETHIOPUM EXTRACT AS A BIOLOGICAL EXTENDER ON SEMEN CHARACTERISTICS, FERTILITY AND HATCHABILITY IN CHICKENS(2017) Adeyina, A. O.; Akanbi, A. S; Okukpe, K. M.; Ogba, I; Alli, O. I.; Adegboye, A. A.; Bolaji, M.Borassus aethiopum extract as a biological extender was evaluated on semen quality, fertility and hatchability in chickens under conditions of warm preservation at 37oC. The extenders were prepared in 1:5 and 1:10 ratios (extract to normal saline) and preserved for 0, 1, 2, 3 and 4 hours respectively in a factorial design layout. There was no significant (p>0.05) effect of the extender on semen characteristics within 2 hours of preservation. However, motility (%) was significantly (p<0.05) reduced when the semen was preserved for more than 2 hours. Interactions between the extender ratios and the period of preservation were significant (p<0.05) for motility (%), dead and abnormal cells. Motility (%) was insignificantly (p>0.05) higher in the extender of 1:10 than in the extender of 1:5 and it was above 70%. Using the extender of 1:10 in the fertility and hatchability trial in a completely randomized design layout showed that fertility decreased, 95% in the 0hour treatment to 73% in the 4-hour treatment while hatchability decreased from 71.4% in the 0-hour treatment to 61.5% in the 4-hour treatment. It may be concluded that the Borassus aethiopum extract could be used to extend and preserve the semen of chickens for 3 hours providing good fertility and hatchability of eggs.Item Haematological, Serum Biochemical and Histopathological Changes in Acute and Sub-Chronic Aqueous Extract of Oyster Mushroom in Male Wistar Rats(Faculty of Sciences, Rajshahi University, Bangladesh., 2023) Garuba, Taofeeq; Olabanji, Islamiyat T.; Awogboro, Mariam O.; Olahan, Ganiyu S.; Atunwa, Soliu A.; Ahmed, Akeem O.; Aremu, Abdulfatai; Bolaji Mashhod; Adegboye, A. A.; Sabiu, SaheedThis study aimed at evaluating toxicological implications of aqueous P. ostreatus extract (POE) in male Wistar rats. POE was prepared in 1:10 (pulverized P. ostreatus : distilled water). In acute toxicity test, single oral dose of 2 mL/kg of POE was administered and observed for 28 days. The sub-chronic toxicity study was conducted by daily oral administration of graded doses (0.25, 0.50 and 0.75 mL/kg b.w) of the extract for 28 days. Clinical signs of toxicity, hematological, serum biochemical parameters and histopathological studies were subsequently evaluated. No treatment-related signs of toxicity or mortality in the animals were recorded in both toxicity tests. Rats administered with lowest dose of POE (25 mL/kg) had highest percentage weight gain. POE had no significant difference (P>0.05) on Red Blood Cell, White Blood Cell (WBC) and differential WBC, and serum biochemistry across all the treated groups when compared to the controls. The result of photomicrographs of stomach, spleen, heart, lung, kidney and liver showed a well outlined arrays of normal tissues in both acute and sub-chronic doses connoting that POE had no toxic effect on them. In view of these, POE may be concluded to be non-toxic within the tested doses and period of investigation