Browsing by Author "Adedoyin, Olanrewaju Timothy"
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Item Current trends in the management of acute kidney injury in children(Paediatric Association of Nigeria, 2013) Katibi, Oludolapo; Adedoyin, Olanrewaju Timothy; Anoba, Suleiman; Sowumi, F O; Olorunsola, Benjamin O; Ibrahim, O R; Oyeleye, A E; Katibi, O SAcute Kidney Injury (AKI) previously known as acute renal failure (ARF) is a common problem in the paediatric emergency wards with infections like sepsis and malaria being the commonest causes in Nigeria. It has been known by various nomenclatures with a lack of standardised definition. This has made comparison of data very difficult. In the last decade, attempts have been made to standardize the definition by developing a classification criterion termed “RIFLE”. This is in turn undergoing various modifications with the most recent classification system developed by the Kidney Disease: Improving Global Outcomes (KDIGO). Despite these interesting developments, the basis of these classifications which is the use of serum creatinine measurements is fraught with its own limitations. This has led to discovery of various urinary and serum biomarkers like the cystatin C and neutrophil gelatinase associated lipocalin (NGAL) which appear to have very promising advantages over the well known creatinine measurements. Management of AKI continues to be anticipatory with appropriate fluid therapy and adequate treatment of infections. The benefits of furosemide and dopamine in management are still a constant source of debate. Treatment of life threatening complications like hyperkalaemia and hypertension as well as maintaining the kidney through the period of non-function can lead to remarkable recovery of renal homeostatic function.Item Prevalence of Hypertension and Relationship with Anthropometric Indices in Urban Dwellers in Kwara State, Nigeria(Medical Research Society, College of Health Sciences, Nnamdi Azikiwe University, Awka, Nigeria, 2023-03-01) Olanrewaju, Timothy Olusegun; Aderibigbe, Ademola; Popoola, Ademola; Buhari, Mikhail Olayinka; Adedoyin, Olanrewaju Timothy; Kuranga, Sulyman Alege; Biliaminu, Sikiru Abayomi; Chijioke, Adindu; Ajape, Abdulwahab Akanbi; Dada, Samuel Ayokunle; Obajolowo, OmotolaBackground: Hypertension is a growing public health concern with a rising prevalence and associated clinical outcomes, particularly in Nigeria. The association of hypertension with anthropometric indices is insufficiently described in Nigeria. Objectives: We aim to determine the prevalence of hypertension and its relationship with anthropometric indices. Materials and Methods: This is a cross-sectional study of adults in seven urban communities in Kwara State, Nigeria. The study was done during World Kidney Day over a seven year period (2007-2015). Blood pressure, body mass index, waist circumference, and hip circumference were measured. Hypertension was defined as blood pressure ≥ 140/90mmHg. Results: One thousand five hundred and six adults were recruited, with a mean age of 44 ± 14 years, and a female preponderance (55%). The prevalence of hypertension was 30%, (30.2%) in males and (29.8% in females). Hypertension correlates significantly with age (r = 0.416, P = 0.001), BMI (r = 0.301, P = 0.001), hip circumference (r = 0.219, P = 0.001), waist-hip ratio (r = 0.225, P = 0.005), and waist circumference (r = 0.063, P = 0.045). The identified predictors of hypertension were; waist circumference had about 17% increased risk for hypertension (OR = 1.169, CI = 1.021 – 1.340, P = 0.024), body mass index, 11% (OR = 1.113, CI = 1.059–1.170, P = 0.001), and age 5% (OR = 1.052, CI = 1.034 – 1.070, P = 0.001).Conclusion:The prevalence of hypertension is high in urban population of Kwara State, and is similar in men and women, but it increases with age, high body mass index, and waist circumference.