Browsing by Author "Adedeji, Adeyinka"

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    Natural outbreak of Marek’s disease in indigenous chicken and Japanese quail (Coturnix coturnix japonica) in Jos, Plateau State, Nigeria
    (Open Veterinary Journal, 2019-05-24) Adedeji, Adeyinka; Akanbi, Olatunde; Luka, Pam; Abdu, Paul
    Carcasses of an indigenous adult chicken and Japanese quail from different flocks were presented to a veterinary clinic for postmortem (PM) examination in 2014 in Jos, Plateau State, Nigeria. PM observations revealed cutaneous, hepatic, and splenic tumors in the Indigenous chicken. The quail carcass was emaciated with hepatic tumors. Histopathology revealed severe focally extensive non-encapsulated circumscribed large nodules with pleomorphic population of cells mainly composed of lymphoplasmacytic and mixed neutrophilic polymorphonuclear cells in the chicken. The pleomorphic infiltration of lymphohistioplasmacytic cells mixed with neutrophilic polymorphonuclear cells in the quail was consistent with Marek’s disease virus (MDV) infection. Polymerase chain reaction (PCR) was carried out, and the Meq oncogene of the MDV was amplified in the samples collected from the chicken and quail to confirm the presence of the virulent MDV. The samples were also subjected to PCR for detection of MDV Rispens CVI988 vaccine strain which was detected in both chicken and quail samples. The findings in this study represent the first report of confirmatory diagnosis of MD using histopathology in an indigenous chicken and Japanese quail in Nigeria. It is also the first report of the detection of MDV Rispens CVI988 vaccine strain in unvaccinated chicken and quail in Nigeria.
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    Outbreak of Lumpy skin disease in a dairy farm in Keffi, Nasarawa State, Nigeria
    (Sokoto Journal of Veterinary Sciences, 2018-09) Adedeji, Adeyinka; Akanbi, Olatunde; Adole, J A; Chima, N C; Baje, M
    A dairy farm in Keffi, Nasarawa State, North Central Nigeria reported cases of skin infections in cattle suggestive of lumpy skin disease (LSD) in the years 2014 and 2016. During the 2016 outbreak, skin biopsies were collected for laboratory investigation using histopathology and polymerase chain reaction (PCR). The samples were subjected to PCR using two sets of primers which amplified the G-protein-coupled chemokine receptor (GPCR) gene and RNA polymerase subunit gene (RPO30) of the LSD virus (LSDV). Clinical signs observed in the two outbreaks were similar and included ocular and nasal discharges, nodular skin lesion, and pyrexia and reduced milk production. Morbidity rate was 6.25% (25/400) in 2014 and the mortality rate was 2.5% (10/400). Furthermore, the second outbreak in 2016 had a morbidity and mortality rates of 5% (20/400) and 0.5 % (2/400) respectively. From animals that died in the 2014 outbreak, necropsy findings included nodular lesions on the skin, muzzle, in the buccal cavity and nasal mucosa. Also, congested and oedematous lungs and enlarged lymph nodes were observed. The nodular skin lesions observed during the 2016 outbreak were larger and more numerous lesions in the Sokoto Gudali. While the Holstein Friesian cross had smaller gross skin nodules with acute to sub-acute histopathologic changes. The histopathological examination of the skin biopsy of the HF was consistent with LSD viral lesions, while PCR detected the RPO30 and GPCR gene fragments of LSDV.
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    SEVERE CUTANEOUS BOVINE PAPILLOMATOSIS IN A CATTLE HERD
    (Vom Journal of Veterinary Science, 2008) Zwandor, N J; Akalusi, Y; Ngulukun, S; Meseko, Clement; Akanbi, Olatunde; Adedeji, Adeyinka; Fagbamila, I
    A 5-month old zebu calf was noticed with wart-like growths on the head. These were removed surgically and tetracycline was administered. One Friesian bull in the herd was also noticed to have crusty lesions suspected to be dermatophilosis based on previous exposure, and was treated with lamstreptocide. A few months later, wartlike lesions were observed on the dorsum which later spread to other parts of the body and also spread to other animals in the herd. Papillomatosis and lumpy skin disease were suspected and samples were taken to histopathology and virology laboratories of NVRI where papillomatosis was confirmed based on clinical signs and histopathological findings. Cutaneous Bovine Papillomatosis (CBP) is a disease of economic importance, affecting breeding, hides and dairy industries. There is therefore a need for proper documentation of cases in order to determine the status of the disease in Nigeria.