Browsing by Author "Abdulkarim, Aishatu"

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    Childhood pneumonia seen at University of Ilorin Teaching Hospital, Nigeria
    (Peadiatric Association of Nigeria, 2013) Abdulkarim, Aishatu; Ibraheem, Rasheedat; Adegboye, Abdulrasheed; Johnson, 'Wahab; Adeboye, Muhammed
    Background/Objectives:Pneumonia is a leading cause of morbidity and mortality in children and thus this study was designed to document the sociodemographic, clinical features as well as the bacterial agents responsible for pneumonia in children seen at University of IlorinTeaching Hospital. Methodology: A descriptive cross-sectional study of children aged one month to 14 years with features of pneumonia admitted between July 1st 2010 and June 31st,2011 was carried out. Sociodemograpic data, clinical features, complications and outcome were obtained. Chest radiographs and blood samples for culture of bacterial organism and full blood counts were obtained in all children. Results: Pneumonia accounted for 13.3% (167 out of 1254) of the all admissions during this period. The male: female ratio was 1.5:1, and 101(60.5%) of the children were infants. Bronchopneumonia was identified in 147(88%) children, lobar pneumonia in 15 (9%) while 5(3%) had a combination of both. Cough, fever, difficulty in breathing, tachypnoea and chest wall recessions were recognized as clinical features in the study population. Bacteraemia was present in 46(27%)children and Staphylococcus aureus was the most common organism cultured from the blood of children with pneumonia present in 11 (23.9%) out of the 46 (100.0%) isolates. Heart failure was associated complication present in 52 of the 60 children with one or more complications accounting for over 30% of all patients. Eleven out of the 15 children with lobar pneumonia had pneumonia-related complications which was significantly higher compared to 46 of 157 children with bronchopneumonia, p=0.003. The case fatality was 6.6%. Eight (72.7%) of the children that died were infants while the remaining three (27.3%) were aged between 12 and 60 months. The mean duration of hospitalization among those who survived of 6.5 ±5.0 days was significantly lower than the corresponding value of 10.2 ±12.3 days in those that died, p= 0.042. Conclusion: Pneumonia-related mortality and morbidity is high in under-five children, with the infant age group most affected. Bronchopneumonia is the most prevalent ALRI diagnosis but lobar pneumonia is associated with a higher mortality.
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    Serum zinc levels as a predictor of clinical features and outcome of paediatric acute lower respiratory infections in Nigeria.
    (Peadiatric Association of Nigeria, 2013) Ibraheem, Rasheedat; Johnson, 'Wahab; Abdulkarim, Aishatu; Abdulkadir, Mohammed; Oladele, Damilola; Biliaminu, Sikiru
    Background: Malnutrition, especially macronutrient deficiency, has been shown to be interrelated with ALRI-related morbidity and mortality. However the import of zinc deficiency has only recently become the focus of research attention. Objective: The current study was carried out in Ilorin, Kwara State, Nigeria to determine the relationship between serum zinc levels, clinical features and outcome in hospitalized children with acute lower respiratory infections (ALRI). Method: A descriptive cross-sectional hospital-based study involving 120 children aged two months to five years with ALRI. Socio-demographic, clinical and laboratory data were obtained. The serum zinc was analyzed with a Jenway™ spectrophotometer after initial preparation with the QuantiChrom™ zinc assay kit. Results: Children with tachypnoea and crepitations had significantly lower mean serum zinc levels compared to the corresponding values in those without these features (each p<0.05). Significantly higher mean serum zinc level was recorded in children with grunting respiration compared with those without grunting (p=0.028). Age-related tachypnoea, grunting, and crepitations remained significant (each p<0.05) following a linear regression analysis. The mean serum zinc level in children with multiple complications was significantly lower than the corresponding level recorded in children who had one complication, p=0.020. No significant difference was found between the mean serum zinc level of the children who were discharged compared with the corresponding level recorded in those that died, p=0.589. Conclusion: The presence of crepitations had the strongest clinical association with a low serum zinc level. Children managed for ALRI would benefit from post-treatment zinc supplements and appropriate zinc-rich sources of food at discharge.
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    Serum zinc levels in hospitalized children with acute lower respiratory infections in the North-Western region of Nigeria.
    (College of Medicine, University of Makerere, Uganda, 2014-03) Ibraheem, Rasheedat; Johnson, W B R; Abdulkarim, Aishatu; Biliaminu, S.A.
    Background: Macronutrient deficiency has continued to attract significant research interest, where as the import of micronutrients like zinc has only recently become the focus of interest. Thus against the background of a dearth of data on zinc levels in Nigerian children with Acute Lower Respiratory Infection (ALRI), this study was carried out in Ilorin, Nigeria to determine the serum zinc levels in hospitalized children with ALRI. Methodology: A comparative cross-sectional hospital based study involving 120 children aged two months to five years with ALRI recruited as subjects, and 120 age- appropriate controls without ALRI was carried out. Socio-demographic, clinical and laboratory data were obtained. The serum zinc was analyzed with a Jenway™ spectrophotometer after an initial preparation with the QuantiChrom™ zinc assay kit. Results: The male/ female ratio was 1.6:1. The mean (SD) serum zinc level in subjects with ALRI of 18.7(11.8)µg/dl was significantly lower than the corresponding value of 53.1(18.5)µg/dl recorded in the controls, p=0.001. The prevalence of 98.3% for low serum zinc levels recorded in children with ALRI was significantly higher than that recorded in controls of 64.2%, p=0.001. Conclusion: Low serum zinc levels are significantly associated with ALRI. There is a need to determine whether hospitalized children managed for ALRI might benefit from post discharge zinc supplementation.
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    Vaccines and Immunization: The past, present and future in Nigeria
    (Peadiatric Association of Nigeria, 2011) Abdulkarim, Aishatu; Ibrahim, Rasheedat; Fawi, A; Adebayo, Olubunmi; Johnson, 'Wahab