Browsing by Author "Abdulkadir, M. B."
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Item A Prospective Study of Spectrum, Risk Factors and Immediate Outcome of Congenital Anomalies in Bida, North Central Nigeria.(Department of Pediatrics, College of Health Sciences, University of Ilorin Teaching Hospital, 2017) Adeboye, M. A. N.; Abdulkadir, M. B.; Adegboye, O. A.; Saka, A. O.; Oladele, P. D.; Oladele, D. M.; Eze, E. C.; Adeyemi, O. O.; Abubakar, U.; Grace, A.; Rotimi, B. F.Background: Congenital disorders are structural, metabolic, behavioral and functional disorders that are present at birth. Their manifestations are protean ranging from mild anomalies to life‑threatening conditions. Aim: The objectives of this study were to describe the congenital anomalies in children seen at Federal Medical Center, Bida over a 12 month period, determine possible factors associated with these anomalies; and their short term outcome. Subjects and Methods: Children with clinically recognized congenital malformations were recruited consecutively over a 12 month period and socio‑demographic, etiologic and other relevant clinical data were obtained. A detailed examination was also performed and abnormalities documented. The data was analyzed using Epi‑info version 6 (Atlanta, USA). The Chi‑square was used to identify significant differences for categorical variables. Mid‑P and Fisher’s exact tests were utilized as appropriate. A P < 0.05 was considered to be significant. Results: A total of 46 children with congenital anomalies were seen during the study period, all which were recruited into the study. The hospital based prevalence amongst neonates was 111/1000 neonates. The most common system affected was the digestive system (50.0%) followed by the central nervous system and head and neck anomalies. There was no significant difference in distribution of anomalies amongst the various ethnic groups. About 22% of families were consanguineous, all being first cousins and 8.7% of mothers were greater than 35 years of age. The case fatality rate for congenital malformations was 2.2%, while 60.9% were referred to other hospitals for further care. Conclusion: The study has demonstrated a wide variety of congenital anomalies in Bida, North‑Central Nigeria with the digestive system anomalies being the most frequent. The findings of this study strengthen the need for empowerment of the institution in appropriate management of these disorders.Item Unusual occurrence of congenital hypothyroidism in a set of same sex triplets: challenges of diagnosis in a resource poor setting(2015-12) Abdulkadir, M. B.; Obasa, T. O.; Ogunkanbi, S. O.; Adeboye, M. A. N.; Adesiyun, O. O.; Makuolu, O. A.Congenital hypothyroidism is the most common endocrinological disorder in children. Genetic and intrauterine factors have been implicated in its aetiology. The aim of this study was to describe an unusual occurrence of congenital hypothyroidism in a set of same sex triplets and challenges associated with the diagnosis. This is a review of a set of female triplets delivered at 34 weeks gestational age and noticed to have reduced activity, hypotonia and poor suck. On testing for thyroid hormones the patients were found to be hypothyroid. However this diagnosis was delayed until the 6th week of life as a result of difficulties in running the test. The subjects of the study were placed on thyroxine supplementation and have been doing well. Congenital hypothyroidism can occur in multiple order pregnancies and clinicians should have a high index of suspicion for its occurrence.