Combined Effects of Leucas aspera, Oxy-Cyclodextrin and Bentonite on the Growth, Serum Biochemistry, and the Expression of Immune-Related Gene in Nile Tilapia (Oreochromis niloticus)

dc.contributor.authorAmitha Kurian
dc.contributor.authorSreeja Lakshmi
dc.contributor.authorFemi John Fawole
dc.contributor.authorCaterina Faggio
dc.contributor.authorPreetham Elumalai
dc.date.accessioned2024-04-26T10:37:37Z
dc.date.available2024-04-26T10:37:37Z
dc.date.issued2020-12-29
dc.description.abstract<jats:p>This study investigated the effects of a combination of Leucas aspera, Oxy-cyclodextrin and sodium bentonite (LOB) on growth, digestive enzyme activity, innate immune response, haematology, and expression of immune-related genes in Nile tilapia. A total of 240 juvenile fish (20.15±0.05g) were randomly distributed into four dietary groups in triplicate and fed respective diets containing a graded level of LOB at 0 g kg-1 (Control), 0.3 g kg-1 (T1), 0.6 g kg-1 (T2) and 0.9 g kg-1 diet (T3) for 60 days. After 60 days, higher growth was observed in fish fed T2 diet (P &lt; 0.05). Digestive enzyme activities and innate immune parameters were significantly higher in T3 group. Some of the haematological parameters reported statistically higher counts in T2 group (P&lt;0.05), whereas erythrocyte indices and WBC counts were significantly higher in T3 group. Liver- kidney activities were recorded low in T3 group. Urea and creatinine were higher in control group, whereas T2 group recorded the least value. The highest relative expression of IL-1β, IgM-heavy chain, TGF-β and IFN-γ were recorded in T2 group, but TNF-α was upregulated in T3 group. The results showed that 0.6 - 0.9 g kg1 of LOB is recommended for inclusion in diet.</jats:p>
dc.identifier.doi10.4194/1303-2712-v21_3_05
dc.identifier.issn1303-2712
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/123456789/13037
dc.publisherCentral Fisheries Research Institute (SUMAE)
dc.relation.ispartofTurkish Journal of Fisheries and Aquatic Sciences
dc.subjectFish health
dc.subjectHerb
dc.subjectImmune genes
dc.subjectInclusion complex
dc.subjectMineral clay
dc.titleCombined Effects of Leucas aspera, Oxy-Cyclodextrin and Bentonite on the Growth, Serum Biochemistry, and the Expression of Immune-Related Gene in Nile Tilapia (Oreochromis niloticus)
dc.typejournal-article
oaire.citation.issue03
oaire.citation.volume21

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