Improved erythrocyte osmotic fragility and packed cell volume following administration of Aloe barbadensis juice extract in rats.

Simple item page
dc.contributor.authorOjulari, Lekan
dc.contributor.authorSafiriyu, A.A
dc.contributor.authorAyinla, M.T
dc.contributor.authorAbdulsalam, J.K
dc.contributor.authorOyabambi, Adewumi O
dc.contributor.authorAdegoke, O.A
dc.date.accessioned2021-06-09T09:13:23Z
dc.date.available2021-06-09T09:13:23Z
dc.date.issued2012-07
dc.description.abstractAloe barbadensis is a popular house plant that has a long history of a multipipose folks remdy. It has been documented to have anti-diabetic, anti-septic and anti-inflammatory effects. The effect of Aloe barbadensis juice extract on erythrocyte osmotic fragility, packed cell volume and haemoglobin concentration in Wistar rats was investigated. Twenty rats were divided into four groups of five rats each. Group A served as control and received distilled water ad libitum, while group B,C and D were the experimental groups and recieved 50mg/kg, 100mg/kg and 150mg/kg body weight of extract respectively, orally for four weeks. The animals were sacrificed and their blood was collected through cardiac puncture. The erythrocyte osmotic fragility packed cell volume and haemoglobin concentration were detrmined. The results showed significant reductions (p<0.05) in the erythrocyte osmotic fragility in the groups that received 100mg/kg and 150mg/kg of the extract when compared to the group and also significant increases (p<0.05) in the packed cell volume of rats that received 50mg/kg and 100mg/kg body weight of the extract. The results suggest dose dependent protective and modulatory effects of aloe barbadensis on the integrity of the erythrocyte membrane and on the packed cell volume respectively.en_US
dc.description.sponsorshipNILen_US
dc.identifier.citationL.S.Ojulari et al/The Tropical Journal of Health Sciences Vol 19 No 2(Jul 2012)en_US
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/6054
dc.language.isoenen_US
dc.publisherCollege of Health Sciencesen_US
dc.relation.ispartofseries19(2):23-26;
dc.subjectOsmotic fragilityen_US
dc.subjectPacked cell volumeen_US
dc.subjectHaemoglobinen_US
dc.subjectAloe veraen_US
dc.titleImproved erythrocyte osmotic fragility and packed cell volume following administration of Aloe barbadensis juice extract in rats.en_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Tropical Journal of Health 1.pdf
Size:
2.05 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections