Pattern of Haematological Changes in Patients with Chronic Kidney Disease Attending Nephrology Clinic in a Tertiary Hospital in North Central Nigeria

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dc.contributor.authorSanni, E.O.
dc.contributor.authorOlawumi, H.O.
dc.contributor.authorDurotoye, I.A.
dc.contributor.authorBabatunde, A.S.
dc.contributor.authorShittu, A.O.
dc.contributor.authorBiliaminu, S.A.
dc.contributor.authorOmokanye, K.O.
dc.contributor.authorOgunfemi, M.K.
dc.contributor.authorAkinwumi, O.O.
dc.contributor.authorOyedepo, D.
dc.contributor.authorDane, S.
dc.date.accessioned2021-10-27T11:23:05Z
dc.date.available2021-10-27T11:23:05Z
dc.date.issued2020
dc.description.abstractIntroduction: The impact of the disease of the kidney is enormous in developing countries like Nigeria. With the increasing use of erythropoietin stimulating agents in anaemic patients with CKD, there is a need to evaluate the changes in haematological parameters in these patients. This study assessed the haematological changes in patients with known chronic kidney disease. Materials and methods: Our research was a cross-sectional study that assessed and compared the haematologic parameters of 113 patients who had established chronic kidney disease and 113 -healthy controls who were age–and sex-matched. The full blood count (FBC) was determined by SysmexKX21(Sysmex, Japan). The test of significance was set at a P- value of <0.05. Results and Discussion: The mean age of patients with CKD was 55.00 + 15.37 years, whilst that of controls was 52.73±13.59 years. (p-value 0.240) The values of the mean of the Hb and RBC among the patients were 9.69+ 2.25g/dl and 3.62 ± 0.92 x 1012/L respectively and were found to be significantly lower than that seen among controls (13.62 ± 1.45 and 4.94 ± 0.62 respectively) with a P-value<0.001. Significantly higher values of the mean WBC and platelet count were found in the patients when compared with the control participants (p-value<0.001). A significant proportion of our patients had microcytic hypochromic anaemia (32%). Conclusion: Careful evaluation of the cause of anaemia and urgent interventions are needed in the managements of these patients.en_US
dc.identifier.citationSanni, E O., Olawumi, H. O., Durotoye, A. I, Babatunde, A. S., Shittu, A. O., Biliaminu, S. A., Omokanye, K. O., Ogunfemi, M. K., Akinwumi, O. O., Oyedepo, D., Dane, S. (2020). Pattern of Haematological Changes in Patients with Chronic Kidney Disease Attending Nephrology Clinic in a Tertiary Hospital in North Central Nigeria, J Res Med Dent Sci, 8 (6): 170-175.en_US
dc.identifier.issn2347-2367
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/6792
dc.language.isoenen_US
dc.publisherAmber Publication Ltden_US
dc.subjectAnaemiaen_US
dc.subjectErythropoietin stimulating agentsen_US
dc.subjectChronic kidney diseaseen_US
dc.subjectHaematological changesen_US
dc.titlePattern of Haematological Changes in Patients with Chronic Kidney Disease Attending Nephrology Clinic in a Tertiary Hospital in North Central Nigeriaen_US
dc.typeArticleen_US

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