Timing of surgery following SARS-CoV-2 infection: An international prospective cohort stud
| dc.contributor.author | Nepogodiev, D. | |
| dc.contributor.author | Simoes, J. Ff | |
| dc.contributor.author | Li, E., | |
| dc.contributor.author | Bhangu, A.............. | |
| dc.contributor.author | ....... Gwadabe Sadiya Musa................. et al | |
| dc.date.accessioned | 2026-05-11T10:49:09Z | |
| dc.date.available | 2026-05-11T10:49:09Z | |
| dc.date.issued | 2021-02-26 | |
| dc.description | article | |
| dc.description.abstract | Summary Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0–2 weeks, 3–4 weeks and 5–6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3–4.8), 3.9 (2.6–5.1) and 3.6 (2.0–5.2), respectively). Surgery performed ≥ 7 weeks after SARS CoV-2diagnosiswasassociatedwithasimilarmortalityrisk tobaseline(oddsratio(95%CI)1.5(0.9–2.1)). After a ≥ 7 weekdelayinundertakingsurgery following SARS-CoV-2 infection, patients with ongoing symptoms hada highermortalitythanpatientswhosesymptomshadresolvedorwhohadbeenasymptomatic(6.0%(95%CI3.2 8.7) vs. 2.4%(95%CI1.4–3.4)vs.1.3%(95%CI0.6–2.0),respectively).Wherepossible,surgeryshouldbedelayed for at least 7 weeksfollowingSARS-CoV-2infection.Patientswithongoingsymptoms≥ 7 weeksfromdiagnosis maybenefitfromfurtherdelay | |
| dc.description.sponsorship | NIHRGlobalHealthResearchUnitonGlobalSurgery,Birmingham,UK | |
| dc.identifier.issn | 0003-2409 | |
| dc.identifier.uri | https://uilspace.unilorin.edu.ng/handle/123456789/18297 | |
| dc.language.iso | en | |
| dc.publisher | Association of Anaesthestetics Great Britain and Ireland. | |
| dc.subject | COVID-19 | |
| dc.subject | delay | |
| dc.subject | SARS-CoV-2 | |
| dc.subject | surgery | |
| dc.subject | timing | |
| dc.title | Timing of surgery following SARS-CoV-2 infection: An international prospective cohort stud | |
| dc.type | Article |