Clinical Presentation and Outcome Of Sinonasal Tumours in A Nigerian Tertiary Health Hospital- 6 Years Review.
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Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Nigerian Medical Journal. Official Publication of Nigerian Medical Association.
Abstract
Background: Sinonasal tumor is an uncommon tumor in Nigeria, but the burden of the disease in terms of morbidity and mortality
is on the increase. The aim of this study is to evaluate the pattern of presentation and outcome of sinonasal tumor in our center.
Methodology: This was a retrospective review of all the patients with sinonasal cancer seen in Ear, Nose, and Throat Department
of the hospital between January 2008 and December 2013. The patients' biodata, clinical presentation, stage of the disease at
presentation, identifiable risk factors, histopathological findings, and outcome were presented. Results: A total of 22 patients were
diagnosed with sinonasal cancer out of 71 patients (31%) with head/neck cancers during the period of study. There were 12 males
(54.5%) and 10 females (45.5%) with a mean age of 51 ± 2.1 years. Epistaxis, nasal blockage, and discharge were seen in all
patients though 41% of patients presented first to the ophthalmologist due to proptosis. Identifiable risk factors were exposure to
wood dust (29%) and petrochemical products in (11%). Most patients presented first at advanced stages of the disease (82%).
Histologically, well-differentiated squamous cell carcinoma was the most common (54.6%) followed by nonintestinal welldifferentiated
adenocarcinoma in 18.2% and plasmacytoma (9.1%). Chemoradiation was the mainstay of management in (38%)
though 13.6% had total maxillectomy with postsurgical chemoradiation and 50.4% defaulted due to cost of management.
Conclusion: Health education on early presentation and efforts at early detection of the disease are needed to achieve cure.
Exposure to the identifiable risk factors should be reduced by protective measures. Easy access to radiotherapy at affordable price
will surely improve the outcome of this disease.
Description
Clinical presentation and outcome of sinonasal tumors in a Nigerian Tertiary Hospital
Keywords
Sinonasal tumor, outcome, clinical presentation
Citation
Alabi BS, Afolabi OA, Omokanye HK, Dunmade AD, Ayodele SO (2017): Clinical Presentation and Outcome Of Sinonasal Tumours in A Nigerian Tertiary Health Hospital- 6 Years Review. Nigerian Medical Journal. 58(3): 92-95