Mixed Isonicotinylhydrazide – pyridoxine Metal omplexes: Synthesis, Characterization and Antimicrobial activity

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dc.contributor.authorLawal, M,
dc.contributor.authorObaleye, J. A.
dc.contributor.authorLawal, A.
dc.contributor.authorBamigboye, M. O.
dc.contributor.authorRajee, A. O.
dc.contributor.authorBabamale, H. F.
dc.contributor.authorNnabuike, G. G.
dc.date.accessioned2019-10-30T14:09:04Z
dc.date.available2019-10-30T14:09:04Z
dc.date.issued2016-05-07
dc.description.abstractSome mixed metal complexes of isonicotinylhydrazide – pyridoxine have been synthesised and characterised by physical and spectroscopic studies such as melting point, conductivity measurement, TLC, FT-IR and UV-visible spectroscopy. The antimicrobial activities of the metal complexes were investigated against some clinical isolates of Eschericha Coli, Klebsiella Pneumonia, Pseudomonas aureginosa and Stapylococcus species using the agar well diffusion method. The result of the spectroscopic studies revealed that both isoniazid and pyridoxine behave as neutral bidentate ligands. The Isonicotinylhydrazide ligand coordinated through the carboxyl oxygen and amine nitrogen while pyridoxine coordinated through the oxygen of the hydroxyl group and nitrogen of the pyridine group. The result of antimicrobial activity shows that the metal complexes displayed higher inhibitory activity against the tested organisms than the parent ligandsen_US
dc.identifier.issn2141-3819
dc.identifier.urihttp://hdl.handle.net/123456789/3201
dc.language.isoenen_US
dc.publisherThe Library and Publications Committee, University of Ilorin, Ilorin, Nigeria.en_US
dc.subjectisonicotinylhydrazideen_US
dc.subjectpyridoxineen_US
dc.subjectsynthesisen_US
dc.subjectmetal complexesen_US
dc.subjectantimicrobial activityen_US
dc.titleMixed Isonicotinylhydrazide – pyridoxine Metal omplexes: Synthesis, Characterization and Antimicrobial activityen_US
dc.title.alternativeCenter point (Science Edition)en_US
dc.typeArticleen_US

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