CHANGES IN SELECTED HAEMATOLOGICAL PARAMETERS OF WISTAR RATS FED WITH FICUS EXASPERATAVAHL LEAF-BASED DIET

Simple item page
dc.contributor.authorSoji-Omoniwa, O
dc.contributor.authorOloyede, H.O.B
dc.date.accessioned2023-07-13T11:53:38Z
dc.date.available2023-07-13T11:53:38Z
dc.date.issued2020
dc.description.abstractIn recent years, there has been increase in the use of non-culinary herbs in food products. This technology of incorporating medicinal or non-culinary herbs into diet offers great promise for the management of diseases.The aim of this study was to evaluate the effect of FicusexasperataVahl leaf-based diet (FELD) on selected haematological parameters of albino rats. Twenty-four rats were randomly selected into 4 groups of 6 animals each namely: C [control rats fed diet without Ficusexasperataleaf (FEL)], F1, F2, and F3 [experimental groups fed diets containing 10 %, 30 % and 50 % FEL respectively]. Rats were allowed access to the compounded feed ad libitum for7 and 21 days. They were thereafter sacrificed and their blood samples collected and analysed using automated haematologic analyser. Results showed significant reduction (p<0.05) in packed cell volume (PCV) and mean cell volume (MCV) after 7 days of consuming FELD while there was a significant increase (p < 0.05) in haemoglobin (HGB), PCV and MCV after 21 days of consuming FELD. The leucocytic parameters showed a significant decrease (p<0.05) in white blood cell (WBC) of rats fed with FELD at all the levels of FEL inclusion compared to control group at the end of day 7 while platelets were significantly reduced at the end of 21 days of consuming FELD. Findings from this study revealed that FELD elicited some level of toxicity as revealed by the observed alterations in the haematological parameters studied.It should therefore be consumed with caution.en_US
dc.identifier.issn2141-3819
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/11487
dc.language.isoen_USen_US
dc.publisherUniversity of Ilorinen_US
dc.subjectFicus exasperata leaf-based dieten_US
dc.subjectPercentage inclusionen_US
dc.subjectHaematological parametersen_US
dc.titleCHANGES IN SELECTED HAEMATOLOGICAL PARAMETERS OF WISTAR RATS FED WITH FICUS EXASPERATAVAHL LEAF-BASED DIETen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Soji-Omoniwa and Oloyede, 2020.pdf
Size:
214.93 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections