Effect of Management on the profile of serum electrolytes, urea and creatinine in children with Nephrotic Syndrome and Acute Glomerulonephritis in Ilorin

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dc.contributor.authorAdedoyin, OT
dc.contributor.authorAnigilaje, EA
dc.contributor.authorOloge, MO
dc.contributor.authorAdeniyi, A
dc.date.accessioned2017-12-04T16:21:17Z
dc.date.available2017-12-04T16:21:17Z
dc.date.issued2006
dc.description.abstractPrimary nephrotic syndrome (NS) and acute glomerulonephritis (AGN) are known to cause varying degrees of renal insufficiency depending on the severity. Certain drugs and management strategies used in these two disorders also have profound effect on the serum electrolyte and urea profiles. This study determines the effect of management on the profile of serum electrolytes, urea and creatinine in children with NS and AGN. A retrospective analysis of the biochemical profiles of children admitted with a diagnosis of NS and AGN between 1996 and 2004 was carried out. A total of 21 and 16 children with AGN and NS respectively met the study criteria. There was no significant difference in the serum sodium, potassium and urea in both groups during the study except at the 4th week. The prevalence of hypokalemia in both groups of children was low. The serum sodium and potassium were significantly low compared to those with AGN in the 4th week, while the serum urea and creatinine was higher in NS patients in the same period. There was also generally a low prevalence of hypokalemia throughout the study period. While the study may have confirmed the occurrence of electrolyte imbalance following the use of diuretics, it has also shown that the prevalence of such electrolyte imbalance in the first 4 weeks of treatment is rather low and insignificant despite using significant dose of the drug.en_US
dc.description.sponsorshipself-sponsoreden_US
dc.identifier.citationAdedoyin OT, Anigilaje EA, Ologe MO and Adeniyi A. (2006) Effect of Management on the profile of serum electrolytes, urea and creatinine in children with Nephrotic Syndrome and Acute Glomerulonephritis in Ilorin. The Tropical Journal of Health Sciences 13(1): 18-22en_US
dc.identifier.issn1117-4153
dc.identifier.urihttp://hdl.handle.net/123456789/85
dc.language.isoenen_US
dc.publisherCollege of Health Sciences, University of Ilorin, Ilorin, Nigeriaen_US
dc.subjectelectrolyte,en_US
dc.subjectnephrotic syndrome,en_US
dc.subjecturea,en_US
dc.subjectacute glomerulopnephritisen_US
dc.subjectchildrenen_US
dc.titleEffect of Management on the profile of serum electrolytes, urea and creatinine in children with Nephrotic Syndrome and Acute Glomerulonephritis in Ilorinen_US
dc.typeArticleen_US

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