Comparative analysis of Amsel criteria and Nugent score in the Diagnosis of Bacterial vaginosis in pregnancy.
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Date
2021-12
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Journal ISSN
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Publisher
Nigerian Society for Microbiology
Abstract
Abstract: The Amsel criteria and Nugent score are common diagnostic methods for BV and efforts continue to establish which method is superior. The study was a prospective cross-sectional study which compared the diagnosis of BV using the Amsel criteria and Nugent score. Participants were 316 consenting antenatal clinic attendees in the second trimester. All participants had two high vaginal swab samples collected which were analyzed using both Amsel criteria and Nugent score. Data analysis was done using SPSS version 20.0 and P<0.05 was considered statistically significant. Among the 316 study participants, the prevalence of BV was 24.1% with Nugent score and 15.5% with Amsel criteria. Also,
post-treatment BV persistence rate was 25.0% with Nugent score and 11.8% with Amsel criteria. Nugent score was superior to Amsel criteria for the diagnosis of BV (χ2=74.764, P0.001). Among 76 women diagnosed BV positive by Nugent score, 36(47.4%) were diagnosed by Amsel criteria while among 240 women diagnosed BV negative with Nugent score, 14(5.8%) were diagnosed as positive by Amsel criteria. Nugent score had a higher sensitivity (93.3% vs. 80.4%), lower specificity (92.1% vs. 94.2%), higher positive (94.0% vs. 72.0%) and negative (90.0% vs. 85.0%) predictive values, lower false positive (2.0% vs. 5.8%) and false negative rate (15.0% vs. 52.6%) and higher accuracy (94.0% vs. 82.9%) compared to Amsel criteria. In conclusion, Nugent score offers an advantage over Amsel criteria in the diagnosis of BV in pregnancy, thus it should be the preferred diagnostic method
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Keywords
Bacterial vaginosis; Nugent score; Amsel criteria; vaginal discharge
Citation
Adeniran, A.S., Ogunniran, B.D., Akanbi II, A.A. & Saidu, R. (2021): Comparative analysis of Amsel criteria and Nugent score in the Diagnosis of Bacterial vaginosis in pregnancy. Nigerian Journal of Microbiology 35(2):5712-5720.